Laparoscopic Assisted Percutaneous Microwave Ablation for Hepatocellular Carcinoma Close to Large Hepatic Vessels

Mohamed Mogahed; Bahaa El Wakeel; Ashraf El Kholy; Wessam Moustafa Abdellatif; Ashraf Anas Zytoon; Mohamed Manaa; Nashwa Said Ghanem

doi:doi:10.11648/j.js.20190705.14

Laparoscopic Assisted Percutaneous Microwave Ablation for Hepatocellular Carcinoma Close to Large Hepatic Vessels

Mohamed Mogahed, Bahaa El Wakeel, Ashraf El Kholy, Wessam Moustafa Abdellatif, Ashraf Anas Zytoon, Mohamed Manaa, Nashwa Said Ghanem

Published in Journal of Surgery (Volume 7, Issue 5)

Received: 13 May 2019 Accepted: 25 June 2019 Published: 29 August 2019

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Abstract

Background: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. It was believed that ablation for tumors close to large vessels should be avoided for the concern of major complications. Microwave ablation (MWA) seemed to be a better choice than radiofrequency ablation (RFA) in treating HCC close to large vessels (≥ 3 mm), for its advantages of a lower susceptibility to heat-sink effects (blood-vessel-mediated cooling), as well as the ability to achieve larger tumor volumes in shorter time. The aim of this study is to evaluate safety and efficacy of MWA for HCC close to large vessels. Methods: 32 patients with 52 HCC lesions were included, all patients have a lesion close to large vessel. 14 patients had single lesion, 16 had two lesions and 2 had three lesions. All patients are Child-Pugh A or B within Milan Criteria and class A disease Barcelona Clinic Liver Cancer (BCLC). Results: This study was conducted on 32 HCC patients 24 males and 8 females with median age 63 years. 32 HCC lesions were close to large vessel while 20 lesions were not close to large vessel. Laparoscopic assisted percutaneous MWA was decided as the treatment of choice for all patients. two patients (6%) had major complications (one patient had right portal vein thrombosis and the other patient had intra-hepatic hematoma), 3 patients (9%) had minor complications in the form of skin burn. Local tumor progression (LTP) occurred in 2 lesions (3.8% of lesions). Conclusion: laparoscopic assisted percutaneous MWA proved to be a safe and effective as a management for HCC close to large vessels.

Published in	Journal of Surgery (Volume 7, Issue 5)
DOI	10.11648/j.js.20190705.14
Page(s)	132-137
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Laparoscopic Assisted Percutaneous, Microwave Ablation, Hepatocellular Carcinoma

References

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APA Style

Mohamed Mogahed, Bahaa El Wakeel, Ashraf El Kholy, Wessam Moustafa Abdellatif, Ashraf Anas Zytoon, et al. (2019). Laparoscopic Assisted Percutaneous Microwave Ablation for Hepatocellular Carcinoma Close to Large Hepatic Vessels. Journal of Surgery, 7(5), 132-137. https://doi.org/10.11648/j.js.20190705.14

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ACS Style

Mohamed Mogahed; Bahaa El Wakeel; Ashraf El Kholy; Wessam Moustafa Abdellatif; Ashraf Anas Zytoon, et al. Laparoscopic Assisted Percutaneous Microwave Ablation for Hepatocellular Carcinoma Close to Large Hepatic Vessels. J. Surg. 2019, 7(5), 132-137. doi: 10.11648/j.js.20190705.14

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AMA Style

Mohamed Mogahed, Bahaa El Wakeel, Ashraf El Kholy, Wessam Moustafa Abdellatif, Ashraf Anas Zytoon, et al. Laparoscopic Assisted Percutaneous Microwave Ablation for Hepatocellular Carcinoma Close to Large Hepatic Vessels. J Surg. 2019;7(5):132-137. doi: 10.11648/j.js.20190705.14

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@article{10.11648/j.js.20190705.14,
  author = {Mohamed Mogahed and Bahaa El Wakeel and Ashraf El Kholy and Wessam Moustafa Abdellatif and Ashraf Anas Zytoon and Mohamed Manaa and Nashwa Said Ghanem},
  title = {Laparoscopic Assisted Percutaneous Microwave Ablation for Hepatocellular Carcinoma Close to Large Hepatic Vessels},
  journal = {Journal of Surgery},
  volume = {7},
  number = {5},
  pages = {132-137},
  doi = {10.11648/j.js.20190705.14},
  url = {https://doi.org/10.11648/j.js.20190705.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20190705.14},
  abstract = {Background: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. It was believed that ablation for tumors close to large vessels should be avoided for the concern of major complications. Microwave ablation (MWA) seemed to be a better choice than radiofrequency ablation (RFA) in treating HCC close to large vessels (≥ 3 mm), for its advantages of a lower susceptibility to heat-sink effects (blood-vessel-mediated cooling), as well as the ability to achieve larger tumor volumes in shorter time. The aim of this study is to evaluate safety and efficacy of MWA for HCC close to large vessels. Methods: 32 patients with 52 HCC lesions were included, all patients have a lesion close to large vessel. 14 patients had single lesion, 16 had two lesions and 2 had three lesions. All patients are Child-Pugh A or B within Milan Criteria and class A disease Barcelona Clinic Liver Cancer (BCLC). Results: This study was conducted on 32 HCC patients 24 males and 8 females with median age 63 years. 32 HCC lesions were close to large vessel while 20 lesions were not close to large vessel. Laparoscopic assisted percutaneous MWA was decided as the treatment of choice for all patients. two patients (6%) had major complications (one patient had right portal vein thrombosis and the other patient had intra-hepatic hematoma), 3 patients (9%) had minor complications in the form of skin burn. Local tumor progression (LTP) occurred in 2 lesions (3.8% of lesions). Conclusion: laparoscopic assisted percutaneous MWA proved to be a safe and effective as a management for HCC close to large vessels.},
 year = {2019}
}

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TY - JOUR
T1 - Laparoscopic Assisted Percutaneous Microwave Ablation for Hepatocellular Carcinoma Close to Large Hepatic Vessels
AU - Mohamed Mogahed
AU - Bahaa El Wakeel
AU - Ashraf El Kholy
AU - Wessam Moustafa Abdellatif
AU - Ashraf Anas Zytoon
AU - Mohamed Manaa
AU - Nashwa Said Ghanem
Y1 - 2019/08/29
PY - 2019
N1 - https://doi.org/10.11648/j.js.20190705.14
DO - 10.11648/j.js.20190705.14
T2 - Journal of Surgery
JF - Journal of Surgery
JO - Journal of Surgery
SP - 132
EP - 137
PB - Science Publishing Group
SN - 2330-0930
UR - https://doi.org/10.11648/j.js.20190705.14
AB - Background: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. It was believed that ablation for tumors close to large vessels should be avoided for the concern of major complications. Microwave ablation (MWA) seemed to be a better choice than radiofrequency ablation (RFA) in treating HCC close to large vessels (≥ 3 mm), for its advantages of a lower susceptibility to heat-sink effects (blood-vessel-mediated cooling), as well as the ability to achieve larger tumor volumes in shorter time. The aim of this study is to evaluate safety and efficacy of MWA for HCC close to large vessels. Methods: 32 patients with 52 HCC lesions were included, all patients have a lesion close to large vessel. 14 patients had single lesion, 16 had two lesions and 2 had three lesions. All patients are Child-Pugh A or B within Milan Criteria and class A disease Barcelona Clinic Liver Cancer (BCLC). Results: This study was conducted on 32 HCC patients 24 males and 8 females with median age 63 years. 32 HCC lesions were close to large vessel while 20 lesions were not close to large vessel. Laparoscopic assisted percutaneous MWA was decided as the treatment of choice for all patients. two patients (6%) had major complications (one patient had right portal vein thrombosis and the other patient had intra-hepatic hematoma), 3 patients (9%) had minor complications in the form of skin burn. Local tumor progression (LTP) occurred in 2 lesions (3.8% of lesions). Conclusion: laparoscopic assisted percutaneous MWA proved to be a safe and effective as a management for HCC close to large vessels.
VL - 7
IS - 5
ER -

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Author Information

Mohamed Mogahed

Surgical Department, National Hepatology & Tropical Medicine Research Institute “NHTMRI”, Cairo, Egypt
Bahaa El Wakeel

Surgical Department, National Hepatology & Tropical Medicine Research Institute “NHTMRI”, Cairo, Egypt
Ashraf El Kholy

Surgical Department, National Hepatology & Tropical Medicine Research Institute “NHTMRI”, Cairo, Egypt
Wessam Moustafa Abdellatif

Radiology Department, National Hepatology & Tropical Medicine Research Institute “NHTMRI”, Cairo, Egypt
Ashraf Anas Zytoon

Radiodiagnosis Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Mohamed Manaa

Tropical Medicine Department, National Hepatology & Tropical Medicine Research Institute “NHTMRI”, Cairo, Egypt
Nashwa Said Ghanem

Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt

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APA Style

Mohamed Mogahed, Bahaa El Wakeel, Ashraf El Kholy, Wessam Moustafa Abdellatif, Ashraf Anas Zytoon, et al. (2019). Laparoscopic Assisted Percutaneous Microwave Ablation for Hepatocellular Carcinoma Close to Large Hepatic Vessels. Journal of Surgery, 7(5), 132-137. https://doi.org/10.11648/j.js.20190705.14

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ACS Style

Mohamed Mogahed; Bahaa El Wakeel; Ashraf El Kholy; Wessam Moustafa Abdellatif; Ashraf Anas Zytoon, et al. Laparoscopic Assisted Percutaneous Microwave Ablation for Hepatocellular Carcinoma Close to Large Hepatic Vessels. J. Surg. 2019, 7(5), 132-137. doi: 10.11648/j.js.20190705.14

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AMA Style

Mohamed Mogahed, Bahaa El Wakeel, Ashraf El Kholy, Wessam Moustafa Abdellatif, Ashraf Anas Zytoon, et al. Laparoscopic Assisted Percutaneous Microwave Ablation for Hepatocellular Carcinoma Close to Large Hepatic Vessels. J Surg. 2019;7(5):132-137. doi: 10.11648/j.js.20190705.14

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@article{10.11648/j.js.20190705.14,
  author = {Mohamed Mogahed and Bahaa El Wakeel and Ashraf El Kholy and Wessam Moustafa Abdellatif and Ashraf Anas Zytoon and Mohamed Manaa and Nashwa Said Ghanem},
  title = {Laparoscopic Assisted Percutaneous Microwave Ablation for Hepatocellular Carcinoma Close to Large Hepatic Vessels},
  journal = {Journal of Surgery},
  volume = {7},
  number = {5},
  pages = {132-137},
  doi = {10.11648/j.js.20190705.14},
  url = {https://doi.org/10.11648/j.js.20190705.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20190705.14},
  abstract = {Background: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. It was believed that ablation for tumors close to large vessels should be avoided for the concern of major complications. Microwave ablation (MWA) seemed to be a better choice than radiofrequency ablation (RFA) in treating HCC close to large vessels (≥ 3 mm), for its advantages of a lower susceptibility to heat-sink effects (blood-vessel-mediated cooling), as well as the ability to achieve larger tumor volumes in shorter time. The aim of this study is to evaluate safety and efficacy of MWA for HCC close to large vessels. Methods: 32 patients with 52 HCC lesions were included, all patients have a lesion close to large vessel. 14 patients had single lesion, 16 had two lesions and 2 had three lesions. All patients are Child-Pugh A or B within Milan Criteria and class A disease Barcelona Clinic Liver Cancer (BCLC). Results: This study was conducted on 32 HCC patients 24 males and 8 females with median age 63 years. 32 HCC lesions were close to large vessel while 20 lesions were not close to large vessel. Laparoscopic assisted percutaneous MWA was decided as the treatment of choice for all patients. two patients (6%) had major complications (one patient had right portal vein thrombosis and the other patient had intra-hepatic hematoma), 3 patients (9%) had minor complications in the form of skin burn. Local tumor progression (LTP) occurred in 2 lesions (3.8% of lesions). Conclusion: laparoscopic assisted percutaneous MWA proved to be a safe and effective as a management for HCC close to large vessels.},
 year = {2019}
}

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