Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review

Biying Huang; Ioannis Gkekas; Ernesto Sparellid

doi:doi:10.11648/j.js.20190704.12

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Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review

Biying Huang, Ioannis Gkekas, Ernesto Sparellid

Published in Journal of Surgery (Volume 7, Issue 4)

Received: 6 May 2019 Accepted: 5 June 2019 Published: 11 July 2019

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Abstract

Liver rupture with severe liver bleeding in patients with amyloidosis is an unusual but generally difficult to deal with and potentially fatal complication in these patients. Even patients with known manifestations to the lever can present with acute lever bleeding. Here we present a case report of a 62-year-old male with systemic immunoglobulin light chain (AL) amyloidosis, known manifestations to the lever and spontaneous liver bleeding which was treated conservatively without the need of surgical intervention. The etiology, panorama of clinical manifestations of hepatic amyloidosis and the management of liver bleeding in association with this unusual disease are reviewed. 18 cases of hepatic rupture and haemorrhage in association with amyloidosis in previously published cases are summarized. The choice of management should be individualized and the patient´s hemodynamic status and extent of liver bleeding are important factors to be taken into consideration. In all patients it is crucial to exclude underlying malignancy as the reason of bleeding. The patient´s hemodynamic status and the extent of liver bleeding are the most important factors to be taken into consideration in order to establish individualized management plan. Increased awareness of severe liver bleeding from amyloidosis may achieve reduced mortality of this potentially fatal complication.

Published in	Journal of Surgery (Volume 7, Issue 4)
DOI	10.11648/j.js.20190704.12
Page(s)	96-100
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Amyloidosis, Spontaneous Liver Bleeding, Case, Review

References

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APA Style

Biying Huang, Ioannis Gkekas, Ernesto Sparellid. (2019). Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review. Journal of Surgery, 7(4), 96-100. https://doi.org/10.11648/j.js.20190704.12

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ACS Style

Biying Huang; Ioannis Gkekas; Ernesto Sparellid. Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review. J. Surg. 2019, 7(4), 96-100. doi: 10.11648/j.js.20190704.12

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AMA Style

Biying Huang, Ioannis Gkekas, Ernesto Sparellid. Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review. J Surg. 2019;7(4):96-100. doi: 10.11648/j.js.20190704.12

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@article{10.11648/j.js.20190704.12,
  author = {Biying Huang and Ioannis Gkekas and Ernesto Sparellid},
  title = {Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review},
  journal = {Journal of Surgery},
  volume = {7},
  number = {4},
  pages = {96-100},
  doi = {10.11648/j.js.20190704.12},
  url = {https://doi.org/10.11648/j.js.20190704.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20190704.12},
  abstract = {Liver rupture with severe liver bleeding in patients with amyloidosis is an unusual but generally difficult to deal with and potentially fatal complication in these patients. Even patients with known manifestations to the lever can present with acute lever bleeding. Here we present a case report of a 62-year-old male with systemic immunoglobulin light chain (AL) amyloidosis, known manifestations to the lever and spontaneous liver bleeding which was treated conservatively without the need of surgical intervention. The etiology, panorama of clinical manifestations of hepatic amyloidosis and the management of liver bleeding in association with this unusual disease are reviewed. 18 cases of hepatic rupture and haemorrhage in association with amyloidosis in previously published cases are summarized. The choice of management should be individualized and the patient´s hemodynamic status and extent of liver bleeding are important factors to be taken into consideration. In all patients it is crucial to exclude underlying malignancy as the reason of bleeding. The patient´s hemodynamic status and the extent of liver bleeding are the most important factors to be taken into consideration in order to establish individualized management plan. Increased awareness of severe liver bleeding from amyloidosis may achieve reduced mortality of this potentially fatal complication.},
 year = {2019}
}

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TY  - JOUR
T1  - Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review
AU  - Biying Huang
AU  - Ioannis Gkekas
AU  - Ernesto Sparellid
Y1  - 2019/07/11
PY  - 2019
N1  - https://doi.org/10.11648/j.js.20190704.12
DO  - 10.11648/j.js.20190704.12
T2  - Journal of Surgery
JF  - Journal of Surgery
JO  - Journal of Surgery
SP  - 96
EP  - 100
PB  - Science Publishing Group
SN  - 2330-0930
UR  - https://doi.org/10.11648/j.js.20190704.12
AB  - Liver rupture with severe liver bleeding in patients with amyloidosis is an unusual but generally difficult to deal with and potentially fatal complication in these patients. Even patients with known manifestations to the lever can present with acute lever bleeding. Here we present a case report of a 62-year-old male with systemic immunoglobulin light chain (AL) amyloidosis, known manifestations to the lever and spontaneous liver bleeding which was treated conservatively without the need of surgical intervention. The etiology, panorama of clinical manifestations of hepatic amyloidosis and the management of liver bleeding in association with this unusual disease are reviewed. 18 cases of hepatic rupture and haemorrhage in association with amyloidosis in previously published cases are summarized. The choice of management should be individualized and the patient´s hemodynamic status and extent of liver bleeding are important factors to be taken into consideration. In all patients it is crucial to exclude underlying malignancy as the reason of bleeding. The patient´s hemodynamic status and the extent of liver bleeding are the most important factors to be taken into consideration in order to establish individualized management plan. Increased awareness of severe liver bleeding from amyloidosis may achieve reduced mortality of this potentially fatal complication.
VL  - 7
IS  - 4
ER  -

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Author Information

Biying Huang

Department of Surgery, Karolinska Institute, Stockholm, Sweden
Ioannis Gkekas

Department of Surgery, Karolinska Institute, Stockholm, Sweden
Ernesto Sparellid

Department of Surgery, Karolinska Institute, Stockholm, Sweden

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Plain Text BibTeX RIS

APA Style

Biying Huang, Ioannis Gkekas, Ernesto Sparellid. (2019). Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review. Journal of Surgery, 7(4), 96-100. https://doi.org/10.11648/j.js.20190704.12

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ACS Style

Biying Huang; Ioannis Gkekas; Ernesto Sparellid. Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review. J. Surg. 2019, 7(4), 96-100. doi: 10.11648/j.js.20190704.12

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AMA Style

Biying Huang, Ioannis Gkekas, Ernesto Sparellid. Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review. J Surg. 2019;7(4):96-100. doi: 10.11648/j.js.20190704.12

Copy | Download

@article{10.11648/j.js.20190704.12,
  author = {Biying Huang and Ioannis Gkekas and Ernesto Sparellid},
  title = {Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review},
  journal = {Journal of Surgery},
  volume = {7},
  number = {4},
  pages = {96-100},
  doi = {10.11648/j.js.20190704.12},
  url = {https://doi.org/10.11648/j.js.20190704.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20190704.12},
  abstract = {Liver rupture with severe liver bleeding in patients with amyloidosis is an unusual but generally difficult to deal with and potentially fatal complication in these patients. Even patients with known manifestations to the lever can present with acute lever bleeding. Here we present a case report of a 62-year-old male with systemic immunoglobulin light chain (AL) amyloidosis, known manifestations to the lever and spontaneous liver bleeding which was treated conservatively without the need of surgical intervention. The etiology, panorama of clinical manifestations of hepatic amyloidosis and the management of liver bleeding in association with this unusual disease are reviewed. 18 cases of hepatic rupture and haemorrhage in association with amyloidosis in previously published cases are summarized. The choice of management should be individualized and the patient´s hemodynamic status and extent of liver bleeding are important factors to be taken into consideration. In all patients it is crucial to exclude underlying malignancy as the reason of bleeding. The patient´s hemodynamic status and the extent of liver bleeding are the most important factors to be taken into consideration in order to establish individualized management plan. Increased awareness of severe liver bleeding from amyloidosis may achieve reduced mortality of this potentially fatal complication.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Amyloidosis and Spontaneous Liver Bleeding: A Case Report and Literature Review
AU  - Biying Huang
AU  - Ioannis Gkekas
AU  - Ernesto Sparellid
Y1  - 2019/07/11
PY  - 2019
N1  - https://doi.org/10.11648/j.js.20190704.12
DO  - 10.11648/j.js.20190704.12
T2  - Journal of Surgery
JF  - Journal of Surgery
JO  - Journal of Surgery
SP  - 96
EP  - 100
PB  - Science Publishing Group
SN  - 2330-0930
UR  - https://doi.org/10.11648/j.js.20190704.12
AB  - Liver rupture with severe liver bleeding in patients with amyloidosis is an unusual but generally difficult to deal with and potentially fatal complication in these patients. Even patients with known manifestations to the lever can present with acute lever bleeding. Here we present a case report of a 62-year-old male with systemic immunoglobulin light chain (AL) amyloidosis, known manifestations to the lever and spontaneous liver bleeding which was treated conservatively without the need of surgical intervention. The etiology, panorama of clinical manifestations of hepatic amyloidosis and the management of liver bleeding in association with this unusual disease are reviewed. 18 cases of hepatic rupture and haemorrhage in association with amyloidosis in previously published cases are summarized. The choice of management should be individualized and the patient´s hemodynamic status and extent of liver bleeding are important factors to be taken into consideration. In all patients it is crucial to exclude underlying malignancy as the reason of bleeding. The patient´s hemodynamic status and the extent of liver bleeding are the most important factors to be taken into consideration in order to establish individualized management plan. Increased awareness of severe liver bleeding from amyloidosis may achieve reduced mortality of this potentially fatal complication.
VL  - 7
IS  - 4
ER  -

Copy | Download