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Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil
Science Journal of Public Health
Volume 4, Issue 3, May 2016, Pages: 224-228
Received: Apr. 18, 2016; Accepted: Apr. 27, 2016; Published: May 14, 2016
Views 3752      Downloads 110
Authors
Ana Carolina Torres, Department of Pathology, Iguaçu University – UNIG, Rio de Janeiro, Brazil
Antonio Neres Norberg, Department of Pathology, Souza Marques Medicine School – FTESM, Rio de Janeiro, Brazil
Fabiano Guerra Sanches, Department of Pathology, Iguaçu University – UNIG, Rio de Janeiro, Brazil
Jose Tadeu Madeira-Oliveira, Department of Pathology, UNIABEU University Center, Rio de Janeiro, Brazil
Alex Nagem Machado, Department of Public Health, Medicine School of Manhuaçu - FACIG, Manhuaçu, Brazil
Paulo Cesar Ribeiro, Department of Pathology, Iguaçu University – UNIG, Rio de Janeiro, Brazil
Nicolau Maues Serra-Freire, Department of Public Health, Oswaldo Cruz Institute – IOC/FIOCRUZ, Rio de Janeiro, Brazil
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Abstract
Syphilis is an infectious disease with worldwide distribution caused by Treponema pallidum, and has great clinical importance when the pathogenesis is in pregnant women. The congenital disease is the result of the infection by vertical transmission of the Treponema to the fetus and can be the cause of high morbidity of the concepts during intrauterine life. It can also cause serious problems during pregnancy such as expontaneous abortus, premature babies with low weight, stillbournes, neonatal mortality, and early or late complications in children who survive to the infection. The aim of this study is to investigate the prevalence of syphilis in pregnants in obstetrics clinics in the Baixada Fluminense region and advise the seropositives for appropriate treatment and evaluate the intervention, contributing to the eradicate to the maternal diseases and preventing the transmission of the Treponema to the concepts. During the years 2010 and 2011, venous blood samples were collected from 1183 asymptomatic adult pregnants accompanied by obstetricians to detect anti-T. pallidum. The serum obtained from the blood was frozen and stored at -20°C until the analysis by serologic reactions of Venereal Disease Research Laboratory (VDRL) and passive hemagglutination (TPHA). The results showed 28 cases were diagnosed with titers equal or superior to 1:16, suggestive of syphilitic disease, corresponding to the coefficient of prevalence of 2.37%. There were dominance of cases in pregnants in the etary group between 21 and 30 years old. There is asymptomatic infection among the examined pregnants of Baixada Fluminense region, with possible risk of vertical transmission of infection to their concepts.
Keywords
Syphilis, Abortus, Stillborn, Drug Treatment (Source: MeSH: MeSH NLM)
To cite this article
Ana Carolina Torres, Antonio Neres Norberg, Fabiano Guerra Sanches, Jose Tadeu Madeira-Oliveira, Alex Nagem Machado, Paulo Cesar Ribeiro, Nicolau Maues Serra-Freire, Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil, Science Journal of Public Health. Vol. 4, No. 3, 2016, pp. 224-228. doi: 10.11648/j.sjph.20160403.20
Copyright
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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