Factors associated with Antiretroviral Treatment Adherence among Adult Patients in Wolaita Soddo Hospital, Wolaita Zone, Southern Ethiopia
Science Journal of Public Health
Volume 2, Issue 2, March 2014, Pages: 69-77
Received: Jan. 2, 2014;
Published: Feb. 28, 2014
Views 3269 Downloads 250
Amsalu Alagaw, Department of Public Health, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia
Wanzahun Godana, Department of Public Health, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia
Mohammed Taha, School of Public Health, College of Health Sciences, Jimma University, Jimma, Ethiopia
Tariku Dejene, School of Public Health, College of Health Sciences, Jimma University, Jimma, Ethiopia
Background: HIV a major challenge to the whole world since the last quarter of 20th century but has become a member of a manageable chronic disease since the advent of ARV drugs. The non-adherence to Antiretroviral Therapy is an emerging major challenge to AIDS care. Objective: To assess factors associated with adherence among AIDS patients receiving Antiretroviral Therapy at Wolaita Soddo Hospital, Southern Ethiopia. Method: A cross sectional study was carried out at Wolaita Soddo Hospital from April 15 to May 15, 2012 E.C. The collected data were entered in Epi Info version3.5.3. Data analyses were done using SPSS for windows version 16.0. Descriptive analysis was used to describe the data. Binary logistic regression analysis was used to measure the association between the dependent variable and independent variables calculating odds ratio and its 95% confidence interval (CI). Statistical significance was set at α. ≤ 0.05. Multivariable analyses were applied to identify the relative effect of explanatory variables on the dependent variable. Results: Three hundred and fifty seven HIV/ AIDS patients were involved in the study. Multi-method adherence assessment consisting of self-report, monthly dispense schedule and dietary requirements ,were used to measure adherence and the average adherence rate was 74.4%.Multivariate logistic regression analysis showed that, with whom a subject lives (AOR=4.943,1,(2.168-11.270)), depression(AOR=2.221,1,(1.093-4.515)), and having inadequate diet to take with ART (AOR=2.229,1,(1.034-4.807)), were independent predictors of dose adherence. Conclusions: In conclusion living with a partner, having no depression and having no food scarcity to take with ART have association with adherence to ART regimens.
Factors associated with Antiretroviral Treatment Adherence among Adult Patients in Wolaita Soddo Hospital, Wolaita Zone, Southern Ethiopia, Science Journal of Public Health.
Vol. 2, No. 2,
2014, pp. 69-77.
Annual Performance Report of HSDP-III, Ministry of Health, Federal Democratic Republic of Ethiopia, EFY2001, (2008/2009)
Health and Health Related Indicators, Federal Ministry of Health, Planning and Programming Department: 2007/8
AIDS Epidemic Update. UNAIDS, World Health Organization. Geneva. WHO 2003
Samuel Sendagala ,Factors affecting the adherence to antiretroviral therapy by hiv positive patients treated in a community based hiv/aids care programme in rural Uganda A case of tororo district ,University Of South Africa ,November 2010
Adherence to HIV Treatment. Geneva, Switzerland. World Health Organization 2004
Bonolo, Palmira de Fae, Casar, Cibele C b, Acurio, Fransisco A ac, et al. Non-adherence among patients initiating antiretroviral therapy: a challenge for health professionals in Brazil. JAIDS. 2006; 19 Sppl4: S5-S13.
Nachega J. B, Stein D M, Lahnan D.A, et al. Adherence to Antiretroviral Therapy in HIVInfected Adults in Soweto, South Africa, AIDS Research and Human Retroviruses. 2004;20(10):1053-1056.
Adriana A, Paola TM, Rita M et al. Correlates and predictors of adherence to Highly Active Antiretroviral Therapy. JAIDS 2002;31 supplement 3:s123-s127.
Eliud Wekesa. ART adherence in resource poor settings in sub-Saharan Africa: a multidisciplinary review
HIV / AIDS IN ETHIOPIA -AN EPIDEMIOLOGICAL SYNTHESIS.Ethiopia HIV/AIDS Prevention & Control Office (HAPCO) and Global HIV/AIDS Monitoring and Evaluation Team (GAMET) april 2008.available at: www.worldbank/aids > publications
Nyambura Anthony Wanjohi. Factors That Influence Non–Adherence To Antiretroviral Therapy Among Hiv And Aids Patients In Central Province, Kenya April 2009.
Alemayehu Amberbir, Kifle Woldemichael, Sofonias Getachew, Belaineh Girma,and Kebede Deribe . Predictors of adherence to antiretroviral therapy among HIV-infected persons: a prospective study in Southwest Ethiopia,july 2008
Yared Mekonnen, Eduard Sanders, Tsehaynesh Messele, Dawit Wolday,Wendelien Dorigo-Zestma, Ab Schaap, Walelgne Mekonnen, Hailu Meless1,Wude Mihret, Arnaud Fontanet, Roel A. Coutinho and Nicole H.T.M. Dukers, Prevalence and Incidence of, and Risk Factors for,HIV-1 Infection among Factory Workers in Ethiopia, 1997-2001
Chesney, MA. 2000. Factors affecting adherence to antiretroviral therapy. Clinical Infectious Diseases 30(2):171-176.
Arnsten, JH, Demas,PA, Farzadegan, H, Grant, RW, Gourevitch, MN, Chang, CJ, Buono, D, Eckholdt, H, Howard, AA, & Schoenbaun, EE .2001. Antiretroviral therapy adherence and viral suppression in HIV-infected drug users: comparison of self-report and electronic monitoring. Clinical Infectious Diseases 33:1417-1423.
Tadios Y, Davey G. Retroviral drug adherence & its correlates in Addis Ababa, Ethiopia; Ethiop Med J 2006; 44:237-244.
Chishimba S and Zulu F. The 3x5 HIV and AIDS Treatment Plan; Challenges for Developing Countries from Zambian Perspective. Int Conf AIDS. (2004). 15: Abstract no. B11132
Orrell C, Bangsberg DR, Badri M, Wood R. Adherence is not a barrier to successful antiretroviral therapy in South Africa. AIDS. 2003;17:1369–75. doi: 10.1097/00002030-200306130-00011.
Sarna A., Luchter S., Giebel S., Munyau P., Kaai S., Shikely K., Mandaliya K., Hawken M., Van Dam J., and Temmerman M. "Promoting adherence to antiretroviral therapy through a directly administered antiretroviral therapy (DAART) strategy in Mombassa Kenya, Horizons Research Update. Nairobi: Population Council. 2005.
Poppa, A., Davidson, D., Deutsch, J., "British HIV Association (BHIVA)/British Association for sexual health and HIV (N‘BASHH) guidelines on provision of adherence support to individuals receiving antiretroviral therapy" HIVMedicine 2004 ,5:S 46-60.
Ekanem Esu Williams,A Study on Social Support and ART Adherence at Carletonville Hospital and Zola Clinic in Gauteng Province.South Africa,2007
Michaels, D, Darder, M; Boulle A; et al; Adherence to antiretroviral treatment: the Experience of patients on ART for longer than 24 months. Oral presentation, 2nd South Africa AIDS Conference Durban, June 2005.