New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies

Mohamed M. Al-Sayed

doi:doi:10.11648/j.bmb.20180301.11

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New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies

Mohamed M. Al-Sayed

Published in Biochemistry and Molecular Biology (Volume 3, Issue 1)

Received: 24 August 2017 Accepted: 8 October 2017 Published: 12 January 2018

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Abstract

Pyrano[2,3-c]pyrazole ligand and their transition metal complex with nickel (Ni^IIMPC) were synthesized and characterization by elemental analyses, magnetic susceptibility, FT IR, UV-Vis, and mass spectroscopy. Complex have been investigated as functional models for catechol oxidase activity by using a catechol as a model substrate. According to the kinetic measurement results, the rate of catechol oxidation follows first order kinetics. Nickel complex has been used in homogenous oxidation of catechol in presence of a green oxidant H₂O2_{. kinetic parameters were obtained V_max= 2.698×10^-3MS^-1, K_m = 7.878M, k_cat= 4.496×10^-2S^-1 and k_cat/K_m = 0.5707 M^-1S^-1.}

Published in	Biochemistry and Molecular Biology (Volume 3, Issue 1)
DOI	10.11648/j.bmb.20180301.11
Page(s)	1-5
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Pyrano[2,3-c]Pyrazole, Nickel, Oxidation, Catecholase

References

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APA Style

Mohamed M. Al-Sayed. (2018). New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies. Biochemistry and Molecular Biology, 3(1), 1-5. https://doi.org/10.11648/j.bmb.20180301.11

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ACS Style

Mohamed M. Al-Sayed. New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies. Biochem. Mol. Biol. 2018, 3(1), 1-5. doi: 10.11648/j.bmb.20180301.11

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AMA Style

Mohamed M. Al-Sayed. New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies. Biochem Mol Biol. 2018;3(1):1-5. doi: 10.11648/j.bmb.20180301.11

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@article{10.11648/j.bmb.20180301.11,
  author = {Mohamed M. Al-Sayed},
  title = {New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies},
  journal = {Biochemistry and Molecular Biology},
  volume = {3},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.bmb.20180301.11},
  url = {https://doi.org/10.11648/j.bmb.20180301.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bmb.20180301.11},
  abstract = {Pyrano[2,3-c]pyrazole ligand and their transition metal complex with nickel (NiIIMPC) were synthesized and characterization by elemental analyses, magnetic susceptibility, FT IR, UV-Vis, and mass spectroscopy. Complex have been investigated as functional models for catechol oxidase activity by using a catechol as a model substrate. According to the kinetic measurement results, the rate of catechol oxidation follows first order kinetics. Nickel complex has been used in homogenous oxidation of catechol in presence of a green oxidant H2O2. kinetic parameters were obtained Vmax= 2.698×10-3MS-1, Km = 7.878M, kcat= 4.496×10-2S-1 and kcat/Km = 0.5707 M-1S-1.},
 year = {2018}
}

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TY  - JOUR
T1  - New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies
AU  - Mohamed M. Al-Sayed
Y1  - 2018/01/12
PY  - 2018
N1  - https://doi.org/10.11648/j.bmb.20180301.11
DO  - 10.11648/j.bmb.20180301.11
T2  - Biochemistry and Molecular Biology
JF  - Biochemistry and Molecular Biology
JO  - Biochemistry and Molecular Biology
SP  - 1
EP  - 5
PB  - Science Publishing Group
SN  - 2575-5048
UR  - https://doi.org/10.11648/j.bmb.20180301.11
AB  - Pyrano[2,3-c]pyrazole ligand and their transition metal complex with nickel (NiIIMPC) were synthesized and characterization by elemental analyses, magnetic susceptibility, FT IR, UV-Vis, and mass spectroscopy. Complex have been investigated as functional models for catechol oxidase activity by using a catechol as a model substrate. According to the kinetic measurement results, the rate of catechol oxidation follows first order kinetics. Nickel complex has been used in homogenous oxidation of catechol in presence of a green oxidant H2O2. kinetic parameters were obtained Vmax= 2.698×10-3MS-1, Km = 7.878M, kcat= 4.496×10-2S-1 and kcat/Km = 0.5707 M-1S-1.
VL  - 3
IS  - 1
ER  -

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Author Information

Mohamed M. Al-Sayed

Chemistry Department, Faculty of Science & Arts Al-Mukhwah, Al-Baha University, Al-Baha, Saudi Arabia

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APA Style

Mohamed M. Al-Sayed. (2018). New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies. Biochemistry and Molecular Biology, 3(1), 1-5. https://doi.org/10.11648/j.bmb.20180301.11

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ACS Style

Mohamed M. Al-Sayed. New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies. Biochem. Mol. Biol. 2018, 3(1), 1-5. doi: 10.11648/j.bmb.20180301.11

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AMA Style

Mohamed M. Al-Sayed. New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies. Biochem Mol Biol. 2018;3(1):1-5. doi: 10.11648/j.bmb.20180301.11

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@article{10.11648/j.bmb.20180301.11,
  author = {Mohamed M. Al-Sayed},
  title = {New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies},
  journal = {Biochemistry and Molecular Biology},
  volume = {3},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.bmb.20180301.11},
  url = {https://doi.org/10.11648/j.bmb.20180301.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bmb.20180301.11},
  abstract = {Pyrano[2,3-c]pyrazole ligand and their transition metal complex with nickel (NiIIMPC) were synthesized and characterization by elemental analyses, magnetic susceptibility, FT IR, UV-Vis, and mass spectroscopy. Complex have been investigated as functional models for catechol oxidase activity by using a catechol as a model substrate. According to the kinetic measurement results, the rate of catechol oxidation follows first order kinetics. Nickel complex has been used in homogenous oxidation of catechol in presence of a green oxidant H2O2. kinetic parameters were obtained Vmax= 2.698×10-3MS-1, Km = 7.878M, kcat= 4.496×10-2S-1 and kcat/Km = 0.5707 M-1S-1.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies
AU  - Mohamed M. Al-Sayed
Y1  - 2018/01/12
PY  - 2018
N1  - https://doi.org/10.11648/j.bmb.20180301.11
DO  - 10.11648/j.bmb.20180301.11
T2  - Biochemistry and Molecular Biology
JF  - Biochemistry and Molecular Biology
JO  - Biochemistry and Molecular Biology
SP  - 1
EP  - 5
PB  - Science Publishing Group
SN  - 2575-5048
UR  - https://doi.org/10.11648/j.bmb.20180301.11
AB  - Pyrano[2,3-c]pyrazole ligand and their transition metal complex with nickel (NiIIMPC) were synthesized and characterization by elemental analyses, magnetic susceptibility, FT IR, UV-Vis, and mass spectroscopy. Complex have been investigated as functional models for catechol oxidase activity by using a catechol as a model substrate. According to the kinetic measurement results, the rate of catechol oxidation follows first order kinetics. Nickel complex has been used in homogenous oxidation of catechol in presence of a green oxidant H2O2. kinetic parameters were obtained Vmax= 2.698×10-3MS-1, Km = 7.878M, kcat= 4.496×10-2S-1 and kcat/Km = 0.5707 M-1S-1.
VL  - 3
IS  - 1
ER  -

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