The Objective of this review was to see the ten year EQA performance trend from 2005 till 2014 at Ethiopian national tuberculosis Reference laboratory. The finding shows that 81.3% and 11.2%of participation were ZN-AFB and of phenotypic DST respectively. The remaining participation was for LPA-PT with proportion of 4.6% and 2.3% for GeneXpert. Most of EQA-PT performance of NTRL scored above 80% and above 90% for Phenotypic DST of 1st and 2nd line Anti-TB drug. DST efficiency reveal that most tested drugs at NTRL were achieved acceptable performance and good agreement result compared to SRLN laboratory test with record data of above 90% for all 1st line and 2nd line drugs with the exception of Ethambutol. Over all TAT record were acceptable with the exception of phenotypic DST which is Critical TAT findings that ranges from 100 to 841 days from total 4 round 1ST and 2nd line DST -PT participation With the median TAT of 205 days. The most frequently committed error type were High false Negative, which accounts 3% contribution for total loss of PT score. The review finding shows there were some gaps on Critical TAT therefore a periodic review and evidence based corrective action has to be made in short time interval after feedback obtained since laboratory error will have devastating impact on clinical management of Patients and laboratory information.
| Published in | American Journal of Laboratory Medicine (Volume 1, Issue 2) |
| DOI | 10.11648/j.ajlm.20160102.11 |
| Page(s) | 5-8 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
AFB-PT, NTRL, NICD, DST, EQA, TAT
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APA Style
Mengistu Tadesse K., Getahun M., Kebede A., Yaregal Z., Meaza A., et al. (2016). Ethiopian National Tuberculosis Reference Laboratory Ten Year External Quality Assurance-Panel Test Performance Review. American Journal of Laboratory Medicine, 1(2), 5-8. https://doi.org/10.11648/j.ajlm.20160102.11
ACS Style
Mengistu Tadesse K.; Getahun M.; Kebede A.; Yaregal Z.; Meaza A., et al. Ethiopian National Tuberculosis Reference Laboratory Ten Year External Quality Assurance-Panel Test Performance Review. Am. J. Lab. Med. 2016, 1(2), 5-8. doi: 10.11648/j.ajlm.20160102.11
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author = {Mengistu Tadesse K. and Getahun M. and Kebede A. and Yaregal Z. and Meaza A. and Dagne Z. and Moga S. and Addise D. and Tesfaye E. and Yenew B. and Mollalign H. and Diriba G. and Girmachew F. and Dimssea D. and Marondera B.},
title = {Ethiopian National Tuberculosis Reference Laboratory Ten Year External Quality Assurance-Panel Test Performance Review},
journal = {American Journal of Laboratory Medicine},
volume = {1},
number = {2},
pages = {5-8},
doi = {10.11648/j.ajlm.20160102.11},
url = {https://doi.org/10.11648/j.ajlm.20160102.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20160102.11},
abstract = {The Objective of this review was to see the ten year EQA performance trend from 2005 till 2014 at Ethiopian national tuberculosis Reference laboratory. The finding shows that 81.3% and 11.2%of participation were ZN-AFB and of phenotypic DST respectively. The remaining participation was for LPA-PT with proportion of 4.6% and 2.3% for GeneXpert. Most of EQA-PT performance of NTRL scored above 80% and above 90% for Phenotypic DST of 1st and 2nd line Anti-TB drug. DST efficiency reveal that most tested drugs at NTRL were achieved acceptable performance and good agreement result compared to SRLN laboratory test with record data of above 90% for all 1st line and 2nd line drugs with the exception of Ethambutol. Over all TAT record were acceptable with the exception of phenotypic DST which is Critical TAT findings that ranges from 100 to 841 days from total 4 round 1ST and 2nd line DST -PT participation With the median TAT of 205 days. The most frequently committed error type were High false Negative, which accounts 3% contribution for total loss of PT score. The review finding shows there were some gaps on Critical TAT therefore a periodic review and evidence based corrective action has to be made in short time interval after feedback obtained since laboratory error will have devastating impact on clinical management of Patients and laboratory information.},
year = {2016}
}
TY - JOUR T1 - Ethiopian National Tuberculosis Reference Laboratory Ten Year External Quality Assurance-Panel Test Performance Review AU - Mengistu Tadesse K. AU - Getahun M. AU - Kebede A. AU - Yaregal Z. AU - Meaza A. AU - Dagne Z. AU - Moga S. AU - Addise D. AU - Tesfaye E. AU - Yenew B. AU - Mollalign H. AU - Diriba G. AU - Girmachew F. AU - Dimssea D. AU - Marondera B. Y1 - 2016/09/07 PY - 2016 N1 - https://doi.org/10.11648/j.ajlm.20160102.11 DO - 10.11648/j.ajlm.20160102.11 T2 - American Journal of Laboratory Medicine JF - American Journal of Laboratory Medicine JO - American Journal of Laboratory Medicine SP - 5 EP - 8 PB - Science Publishing Group SN - 2575-386X UR - https://doi.org/10.11648/j.ajlm.20160102.11 AB - The Objective of this review was to see the ten year EQA performance trend from 2005 till 2014 at Ethiopian national tuberculosis Reference laboratory. The finding shows that 81.3% and 11.2%of participation were ZN-AFB and of phenotypic DST respectively. The remaining participation was for LPA-PT with proportion of 4.6% and 2.3% for GeneXpert. Most of EQA-PT performance of NTRL scored above 80% and above 90% for Phenotypic DST of 1st and 2nd line Anti-TB drug. DST efficiency reveal that most tested drugs at NTRL were achieved acceptable performance and good agreement result compared to SRLN laboratory test with record data of above 90% for all 1st line and 2nd line drugs with the exception of Ethambutol. Over all TAT record were acceptable with the exception of phenotypic DST which is Critical TAT findings that ranges from 100 to 841 days from total 4 round 1ST and 2nd line DST -PT participation With the median TAT of 205 days. The most frequently committed error type were High false Negative, which accounts 3% contribution for total loss of PT score. The review finding shows there were some gaps on Critical TAT therefore a periodic review and evidence based corrective action has to be made in short time interval after feedback obtained since laboratory error will have devastating impact on clinical management of Patients and laboratory information. VL - 1 IS - 2 ER -
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