American Journal of Laboratory Medicine

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Effect of Vitamin D deficiency on Lipid Profile

Received: 12 December 2018    Accepted: 27 December 2018    Published: 25 March 2019
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Abstract

The purpose of this study is to investigate the effect of vitamin D deficiency on lipid parameters; cholesterol, triglycerides, low density lipoprotein (LDL), and high density lipoprotein (HDL). Serum level of vitamin D and the lipid parameters were determined in 127 subjects attending private community lab in eastern Amman province, using commercially available kits. Deficiency and insufficiency of vitamin D were 36.2%, 29.9%, respectively. Serum level of cholesterol, triglycerides, and LDL in deficient and insufficient vitamin D subjects were significantly increased, while HDL level was decreased, P-value <0.05. Serum levels of lipid profile and vitamin D in each of the control, insufficient , and deficient groups were all normally distributed due to the fact that P-value is greater than 0.05. Interval plot analysis and One-way ANOVA analysis revealed a significant effect of vitamin D insufficiency or deficiency on serum level of cholesterol, triglycerides, and LDL and increases the levels more than the double. Two samples T-test for every lipid parameter analysis related to subjects in the sufficient, insufficient and deficient vitamin D groups confirm our hypothesis on the effect of vitamin D deficiency on increasing the levels of cholesterol, triglycerides, and LDL and decreasing the level of HDL.

DOI 10.11648/j.ajlm.20190401.12
Published in American Journal of Laboratory Medicine (Volume 4, Issue 1, January 2019)
Page(s) 11-18
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Vitamin D, Cholesterol, Triglycerides, Low Density Lipoprotein, High Density Lipoprotein

References
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Author Information
  • Department of Physiology and Biochemistry and Department of Medical Laboratory Sciences, Faculty of Medicine, Balqa Applied University Medical School (Sabbatical) and Jordan University of Science and Technology, Irbid, Jordan

  • Industrial Engineering Department, Abu Dhabi University and Hashemite University, Zarqa, Jordan

  • School of Medicine, Hashemite University, Zarqa, Jordan

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  • APA Style

    Nabil Ahmad Bashir, Adnan Ahmad Mohammad Bashir, Hani Adnan Bashir. (2019). Effect of Vitamin D deficiency on Lipid Profile. American Journal of Laboratory Medicine, 4(1), 11-18. https://doi.org/10.11648/j.ajlm.20190401.12

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    ACS Style

    Nabil Ahmad Bashir; Adnan Ahmad Mohammad Bashir; Hani Adnan Bashir. Effect of Vitamin D deficiency on Lipid Profile. Am. J. Lab. Med. 2019, 4(1), 11-18. doi: 10.11648/j.ajlm.20190401.12

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    AMA Style

    Nabil Ahmad Bashir, Adnan Ahmad Mohammad Bashir, Hani Adnan Bashir. Effect of Vitamin D deficiency on Lipid Profile. Am J Lab Med. 2019;4(1):11-18. doi: 10.11648/j.ajlm.20190401.12

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  • @article{10.11648/j.ajlm.20190401.12,
      author = {Nabil Ahmad Bashir and Adnan Ahmad Mohammad Bashir and Hani Adnan Bashir},
      title = {Effect of Vitamin D deficiency on Lipid Profile},
      journal = {American Journal of Laboratory Medicine},
      volume = {4},
      number = {1},
      pages = {11-18},
      doi = {10.11648/j.ajlm.20190401.12},
      url = {https://doi.org/10.11648/j.ajlm.20190401.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajlm.20190401.12},
      abstract = {The purpose of this study is to investigate the effect of vitamin D deficiency on lipid parameters; cholesterol, triglycerides, low density lipoprotein (LDL), and high density lipoprotein (HDL). Serum level of vitamin D and the lipid parameters were determined in 127 subjects attending private community lab in eastern Amman province, using commercially available kits. Deficiency and insufficiency of vitamin D were 36.2%, 29.9%, respectively. Serum level of cholesterol, triglycerides, and LDL in deficient and insufficient vitamin D subjects were significantly increased, while HDL level was decreased, P-value <0.05. Serum levels of lipid profile and vitamin D in each of the control, insufficient , and deficient groups were all normally distributed due to the fact that P-value is greater than 0.05. Interval plot analysis and One-way ANOVA analysis revealed a significant effect of vitamin D insufficiency or deficiency on serum level of cholesterol, triglycerides, and LDL and increases the levels more than the double. Two samples T-test for every lipid parameter analysis related to subjects in the sufficient, insufficient and deficient vitamin D groups confirm our hypothesis on the effect of vitamin D deficiency on increasing the levels of cholesterol, triglycerides, and LDL and decreasing the level of HDL.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Effect of Vitamin D deficiency on Lipid Profile
    AU  - Nabil Ahmad Bashir
    AU  - Adnan Ahmad Mohammad Bashir
    AU  - Hani Adnan Bashir
    Y1  - 2019/03/25
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ajlm.20190401.12
    DO  - 10.11648/j.ajlm.20190401.12
    T2  - American Journal of Laboratory Medicine
    JF  - American Journal of Laboratory Medicine
    JO  - American Journal of Laboratory Medicine
    SP  - 11
    EP  - 18
    PB  - Science Publishing Group
    SN  - 2575-386X
    UR  - https://doi.org/10.11648/j.ajlm.20190401.12
    AB  - The purpose of this study is to investigate the effect of vitamin D deficiency on lipid parameters; cholesterol, triglycerides, low density lipoprotein (LDL), and high density lipoprotein (HDL). Serum level of vitamin D and the lipid parameters were determined in 127 subjects attending private community lab in eastern Amman province, using commercially available kits. Deficiency and insufficiency of vitamin D were 36.2%, 29.9%, respectively. Serum level of cholesterol, triglycerides, and LDL in deficient and insufficient vitamin D subjects were significantly increased, while HDL level was decreased, P-value <0.05. Serum levels of lipid profile and vitamin D in each of the control, insufficient , and deficient groups were all normally distributed due to the fact that P-value is greater than 0.05. Interval plot analysis and One-way ANOVA analysis revealed a significant effect of vitamin D insufficiency or deficiency on serum level of cholesterol, triglycerides, and LDL and increases the levels more than the double. Two samples T-test for every lipid parameter analysis related to subjects in the sufficient, insufficient and deficient vitamin D groups confirm our hypothesis on the effect of vitamin D deficiency on increasing the levels of cholesterol, triglycerides, and LDL and decreasing the level of HDL.
    VL  - 4
    IS  - 1
    ER  - 

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