American Journal of Laboratory Medicine

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Prevalence of Hepatitis B Virus Infection Among Patients with Chronic Kidney Disease in Jos University Teaching Hospital (JUTH) Jos, Nigeria

Received: 23 September 2017    Accepted: 16 October 2017    Published: 5 December 2017
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Abstract

The frequency of hepatitis B virus in patients with CKD undergoing haemodialysis maintenance has a medical importance in the transmission of the infection and the cause of kidney disease. We aimed to determine sero-prevalence of HBV in patients with chronic kidney disease. A total of 110 blood samples were collected from nephrology Department of Jos University Teaching Hospital and screened for HBsAg marker. HBsAg was detected using rapid chromatographic immunoassays for qualitative detection of HBsAg and was performed using one-step test strips for detection of HBsAg in serum sample. Out of the 110 patients selected, 56 were males and 54 females with an overall 15.5% HBsAg positivity. It was observed that HBsAg positive increases with prolonged duration of haemodialysis maintenance. The prevalence of HBsAg among Chronic Kidney Disease patients is high, however there was no significant association between HBV and chronic kidney disease in this cross-Sectional survey.

DOI 10.11648/j.ajlm.20180301.11
Published in American Journal of Laboratory Medicine (Volume 3, Issue 1, January 2018)
Page(s) 1-5
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

HBV, Infection, Chronic Kidney Disease, JUTH

References
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Cite This Article
  • APA Style

    Jude Yunzoom Nkup, Prisca Ofoeke, Julius Ocheme Okojokwu, Otobo Innocent Ujah, Emeka Ubah Ejeliogu, et al. (2017). Prevalence of Hepatitis B Virus Infection Among Patients with Chronic Kidney Disease in Jos University Teaching Hospital (JUTH) Jos, Nigeria. American Journal of Laboratory Medicine, 3(1), 1-5. https://doi.org/10.11648/j.ajlm.20180301.11

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    ACS Style

    Jude Yunzoom Nkup; Prisca Ofoeke; Julius Ocheme Okojokwu; Otobo Innocent Ujah; Emeka Ubah Ejeliogu, et al. Prevalence of Hepatitis B Virus Infection Among Patients with Chronic Kidney Disease in Jos University Teaching Hospital (JUTH) Jos, Nigeria. Am. J. Lab. Med. 2017, 3(1), 1-5. doi: 10.11648/j.ajlm.20180301.11

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    AMA Style

    Jude Yunzoom Nkup, Prisca Ofoeke, Julius Ocheme Okojokwu, Otobo Innocent Ujah, Emeka Ubah Ejeliogu, et al. Prevalence of Hepatitis B Virus Infection Among Patients with Chronic Kidney Disease in Jos University Teaching Hospital (JUTH) Jos, Nigeria. Am J Lab Med. 2017;3(1):1-5. doi: 10.11648/j.ajlm.20180301.11

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  • @article{10.11648/j.ajlm.20180301.11,
      author = {Jude Yunzoom Nkup and Prisca Ofoeke and Julius Ocheme Okojokwu and Otobo Innocent Ujah and Emeka Ubah Ejeliogu and Joseph Aje Anejo-Okopi},
      title = {Prevalence of Hepatitis B Virus Infection Among Patients with Chronic Kidney Disease in Jos University Teaching Hospital (JUTH) Jos, Nigeria},
      journal = {American Journal of Laboratory Medicine},
      volume = {3},
      number = {1},
      pages = {1-5},
      doi = {10.11648/j.ajlm.20180301.11},
      url = {https://doi.org/10.11648/j.ajlm.20180301.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20180301.11},
      abstract = {The frequency of hepatitis B virus in patients with CKD undergoing haemodialysis maintenance has a medical importance in the transmission of the infection and the cause of kidney disease. We aimed to determine sero-prevalence of HBV in patients with chronic kidney disease. A total of 110 blood samples were collected from nephrology Department of Jos University Teaching Hospital and screened for HBsAg marker. HBsAg was detected using rapid chromatographic immunoassays for qualitative detection of HBsAg and was performed using one-step test strips for detection of HBsAg in serum sample. Out of the 110 patients selected, 56 were males and 54 females with an overall 15.5% HBsAg positivity. It was observed that HBsAg positive increases with prolonged duration of haemodialysis maintenance. The prevalence of HBsAg among Chronic Kidney Disease patients is high, however there was no significant association between HBV and chronic kidney disease in this cross-Sectional survey.},
     year = {2017}
    }
    

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    AU  - Prisca Ofoeke
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    AB  - The frequency of hepatitis B virus in patients with CKD undergoing haemodialysis maintenance has a medical importance in the transmission of the infection and the cause of kidney disease. We aimed to determine sero-prevalence of HBV in patients with chronic kidney disease. A total of 110 blood samples were collected from nephrology Department of Jos University Teaching Hospital and screened for HBsAg marker. HBsAg was detected using rapid chromatographic immunoassays for qualitative detection of HBsAg and was performed using one-step test strips for detection of HBsAg in serum sample. Out of the 110 patients selected, 56 were males and 54 females with an overall 15.5% HBsAg positivity. It was observed that HBsAg positive increases with prolonged duration of haemodialysis maintenance. The prevalence of HBsAg among Chronic Kidney Disease patients is high, however there was no significant association between HBV and chronic kidney disease in this cross-Sectional survey.
    VL  - 3
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Author Information
  • Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Nigeria

  • Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Nigeria

  • Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Nigeria

  • Department of Obstetrics and Gynecology, Jos University Teaching Hospital, Jos, Nigeria

  • AIDS Prevention Initiative in Nigeria, Jos University Teaching Hospital, Jos, Nigeria; Department of Pediatric, University of Jos, Jos, Nigeria

  • Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Nigeria; AIDS Prevention Initiative in Nigeria, Jos University Teaching Hospital, Jos, Nigeria

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