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The Relation Between Age Related Macular Degeneration and Thyroid Disorders

Received: 16 September 2019    Accepted: 18 October 2019    Published: 20 November 2019
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Abstract

The Purpose of the study was to evaluate the association between thyroid -stimulating hormone (TSH), free tri-iodothyronine (T3), free thyroxine (T4), hypothyroidism, hyperthyroidism and age related macular degeneration (ARMD) incidence. Nine hundred and fifty patients with thyroid disorders versus five hundred and thirty eu-thyroid subjects were included in the study during the period from January 2014 to February 2019. Blood pressure, blood sugar level and cholesterol, smoking state were estimated. TSH, T3&T4 were measured. Retinal photography and optical coherence tomography were performed. Patients with hyperthyroidism had increased incidence of ARMD. Patients using thyroxine had also increased incidence of ARMD than non using of thyroxine. There were statistically higher significant percent of marriage, educational level and smoking in patients with thyroid disorders with ARMD than euthyroid (p=0.03. 0.06, 0.001 respectively). In thyroid disorders patients, there were a significant differences between patients had ARMD or had not as regard diabetes, hypertension and cholesterol level (p=0.04, 0.09, 0.03 respectively). We concluded that there were increased incidence of ARMD in both hyperthyroidism, and patients use the thyroxine.

Published in International Journal of Ophthalmology & Visual Science (Volume 4, Issue 4)

This article belongs to the Special Issue The Relation Between Age Related Macular Degeneration and Thyroid Disorders

DOI 10.11648/j.ijovs.20190404.18
Page(s) 101-105
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

TSH, T4, T3, ARMD

References
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[3] Ittermann T, Dorr M, Volzke H, Tost F, Lehmphul I, Kohrle J. High serum thyrotropin levels are associated with retinal arteriolar narrowing in the general population. Thyroid. 2014; 24: 1473–8.
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[5] Aoki Y, Belin RM, Clickner R, Jeffries R, Phillips L, Mahaffey KR. Serum TSH and total T4 in the United States population and their association with participant characteristics: National Health and Nutrition Examination Survey (NHANES 1999–2002) Thyroid. 2007; 17: 1211–23.
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  • APA Style

    Mona Abdelkader, Naglaa Abass. (2019). The Relation Between Age Related Macular Degeneration and Thyroid Disorders. International Journal of Ophthalmology & Visual Science, 4(4), 101-105. https://doi.org/10.11648/j.ijovs.20190404.18

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    ACS Style

    Mona Abdelkader; Naglaa Abass. The Relation Between Age Related Macular Degeneration and Thyroid Disorders. Int. J. Ophthalmol. Vis. Sci. 2019, 4(4), 101-105. doi: 10.11648/j.ijovs.20190404.18

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    AMA Style

    Mona Abdelkader, Naglaa Abass. The Relation Between Age Related Macular Degeneration and Thyroid Disorders. Int J Ophthalmol Vis Sci. 2019;4(4):101-105. doi: 10.11648/j.ijovs.20190404.18

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  • @article{10.11648/j.ijovs.20190404.18,
      author = {Mona Abdelkader and Naglaa Abass},
      title = {The Relation Between Age Related Macular Degeneration and Thyroid Disorders},
      journal = {International Journal of Ophthalmology & Visual Science},
      volume = {4},
      number = {4},
      pages = {101-105},
      doi = {10.11648/j.ijovs.20190404.18},
      url = {https://doi.org/10.11648/j.ijovs.20190404.18},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20190404.18},
      abstract = {The Purpose of the study was to evaluate the association between thyroid -stimulating hormone (TSH), free tri-iodothyronine (T3), free thyroxine (T4), hypothyroidism, hyperthyroidism and age related macular degeneration (ARMD) incidence. Nine hundred and fifty patients with thyroid disorders versus five hundred and thirty eu-thyroid subjects were included in the study during the period from January 2014 to February 2019. Blood pressure, blood sugar level and cholesterol, smoking state were estimated. TSH, T3&T4 were measured. Retinal photography and optical coherence tomography were performed. Patients with hyperthyroidism had increased incidence of ARMD. Patients using thyroxine had also increased incidence of ARMD than non using of thyroxine. There were statistically higher significant percent of marriage, educational level and smoking in patients with thyroid disorders with ARMD than euthyroid (p=0.03. 0.06, 0.001 respectively). In thyroid disorders patients, there were a significant differences between patients had ARMD or had not as regard diabetes, hypertension and cholesterol level (p=0.04, 0.09, 0.03 respectively). We concluded that there were increased incidence of ARMD in both hyperthyroidism, and patients use the thyroxine.},
     year = {2019}
    }
    

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    T2  - International Journal of Ophthalmology & Visual Science
    JF  - International Journal of Ophthalmology & Visual Science
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    AB  - The Purpose of the study was to evaluate the association between thyroid -stimulating hormone (TSH), free tri-iodothyronine (T3), free thyroxine (T4), hypothyroidism, hyperthyroidism and age related macular degeneration (ARMD) incidence. Nine hundred and fifty patients with thyroid disorders versus five hundred and thirty eu-thyroid subjects were included in the study during the period from January 2014 to February 2019. Blood pressure, blood sugar level and cholesterol, smoking state were estimated. TSH, T3&T4 were measured. Retinal photography and optical coherence tomography were performed. Patients with hyperthyroidism had increased incidence of ARMD. Patients using thyroxine had also increased incidence of ARMD than non using of thyroxine. There were statistically higher significant percent of marriage, educational level and smoking in patients with thyroid disorders with ARMD than euthyroid (p=0.03. 0.06, 0.001 respectively). In thyroid disorders patients, there were a significant differences between patients had ARMD or had not as regard diabetes, hypertension and cholesterol level (p=0.04, 0.09, 0.03 respectively). We concluded that there were increased incidence of ARMD in both hyperthyroidism, and patients use the thyroxine.
    VL  - 4
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Author Information
  • Ophthalmology Department, Faculty of Medicine, Mansoura, Egypt

  • Medicine Department, Faculty of Medicine, Mansoura, Egypt

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