International Journal of Ophthalmology & Visual Science
Volume 5, Issue 1, March 2020, Pages: 24-30
Received: Nov. 18, 2019;
Accepted: Jan. 17, 2020;
Published: Jan. 31, 2020
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Marjorie Jeandervin Rah, Vision Care, Bausch & Lomb Incorporated, Rochester, USA
William Thomas Reindel, Vision Care, Bausch & Lomb Incorporated, Rochester, USA
Cynthia Denise Adams, Healthcare Insights, Engine, Princeton, USA
Melissa Arielle Brostoff, Healthcare Insights, Engine, Princeton, USA
Lisbeth Anne Wilson, Strategic Insights, Bausch Health, Bridgewater, USA
Howard Marc Proskin, Howard M. Proskin & Associates, Rochester, USA
Purpose: Video gaming is popular worldwide, and its benefits and risks have come to the attention of health care providers across disciplines. Blink rate, blink amplitude, and tear film stability are compromised during dynamic, prolonged use of digital devices, which can result in symptoms of discomfort with contact lens wear. In addition to lens material and design, the choice of lens care cleaning and disinfecting solution can affect wearer satisfaction. The purpose of this evaluation was to compare real world experiences with a hyaluronan-containing contact lens multipurpose solution (MPS) among subjects classified as video gamers and non-gamers. Methods: This study was a prospective, single arm, open label survey of contact lens wearers who used a computer, smartphone, or tablet for a minimum of three hours daily. Contact lens-wearing gamers (subjects who reported that they play electronic games while wearing contact lenses 2-hours or more daily) and non-gamers were provided Biotrue MPS to use for at least seven-days while wearing a fresh pair of their respective habitual contact lenses. Subjects rated performance attributes via an online survey using a 6-point Likert scale. Results: At baseline, gamers were younger than non-gamers, more likely male, spent more time using digital devices daily, and were more likely to report they suffer from eyestrain, sensitive eyes, and red eyes. Both groups rated all queried lens-wearing performance attributes positively; gamers gave higher mean ratings than did non-gamers to 23 of 24 queried attributes, including all four pertaining to long durations of digital device use. After adjusting for both age and gender, significant differences favoring gamers were noted for all 24 attributes. Conclusions: Contact lens wearing gamers and non-gamers rated Biotrue MPS highly based upon various performance attributes. Biotrue MPS remains a good choice for general lens wear, as well as during tear film-challenging video game play.
Marjorie Jeandervin Rah,
William Thomas Reindel,
Cynthia Denise Adams,
Melissa Arielle Brostoff,
Lisbeth Anne Wilson,
Howard Marc Proskin,
Assessment of a Multipurpose Solution by Video Gamers and Non-gamers, International Journal of Ophthalmology & Visual Science.
Vol. 5, No. 1,
2020, pp. 24-30.
Higinbotham WA. BNL Tennis Game. Deposition of April 29, 1976. Available from: https://www.bnl.gov/about/docs/Higinbotham_Deposition.pdf. Accessed November 18, 2019.
This Month in Physics History. October 1958: Physicist invents first video game. APS News. 2008; 17 (9): 2. Available from: https://www.aps.org/publications/apsnews/200810/upload/October-2008-Volume-17-Number-9-Entire-Issue.pdf. Accessed November 18, 2019.
2019 Essential Facts about the Computer and Video Game Industry. Washington, DC: The Entertainment Software Association (ESA) 2018. Available from: https://www.theesa.com/wp-content/uploads/2019/05/2019-Essential-Facts-About-the-Computer-and-Video-Game-Industry.pdf. Accessed November 18, 2019.
Flamberg M. U.S. Games 360 Report: 2018. Nielsen Holdings plc 2018; pp 6-8. Available from: http://www.nielsen.com/us/en/insights/reports/2018/us-games-360-report-2018.html. Accessed November 18, 2019.
2015 Sales, Demographic and Usage Data. Essential Facts about the Computer and Video Game Industry. Washington, DC: The Entertainment Software Association (ESA) 2015. Available from: https://templatearchive.com/esa-essential-facts/. Accessed November 18, 2019.
2017 Sales, Demographic and Usage Data. Essential Facts about the Computer and Video Game Industry. Washington, DC: The Entertainment Software Association (ESA) 2018. Available from: https://www.theesa.com/wp-content/uploads/2019/03/ESA_EssentialFacts_2017.pdf. Accessed November 18, 2019.
Rechichi C, De Mojà G, Aragona P. Video game vision syndrome: a new clinical picture in children? [J]. Pediatr Ophthalmol Strabismus. 2017; 54 (6): 346-355.
Wittek CT, Finserås TR, Pallesen S, Mentzoni RA, Hanss D, Griffiths MD, Molde H. Prevalence and predictors of video game addiction: a study based on a national representative sample of Gamers. Int J Ment Health Addict. 2016; 14 (5): 672-686.
Blehm C, Vishnu S, Khattak A, Mitra S, Yee RW. Computer vision syndrome: a review. Surv Ophthalmol. 2005; 50 (3): 253-262.
Rosenfield M. Computer vision syndrome: a review of ocular causes and potential treatments. Ophthalmic Physiol Opt. 2011; 31 (5): 502-515
Thevisioncouncil.org [homepage on the Internet]. Hindsight is 20/20/20: Protect Your Eyes form Digital Devices. 2015 Digital Eye Strain Report. Alexandria, VA: The Vision Council. 2015 [cited July 1, 2019]. Available from: https://www.pcom.ph/sites/default/files/downloads/vc_digitaleyestrain_report2015.pdf. Accessed November 18, 2019.
Porcar E, Pons AM, Lorente A. Visual and ocular effects from the use of flat-panel displays. Int J Ophthalmol. 2016; 9 (6): 881–885.
Patel S, Henderson R, Bradley L, Galloway B, Hunter L. Effect of visual display unit use on blink rate and tear stability. Optom Vis Sci. 1991; 68 (11): 888-892.
Tsubota K, Nakamori K. Dry eyes and video display terminals. N Engl J Med. 1993; 328 (8): 584
Wolkoff P, Nøjgaard JK, Troiano P, Piccoli B. Eye complaints in the office environment: precorneal tear film integrity influenced by eye blinking efficiency. Occup Environ Med. 2005; 62 (1): 4-12.
Cardona G, García C, Serés C, Vilaseca M, Gispets J. Blink rate, blink amplitude, and tear film integrity during dynamic visual display terminal tasks. Curr Eye Res. 2011; 36 (3): 190-197.
Bentivoglio AR, Bressman SB, Cassetta E, Carretta D, Tonali P, Albanese A. Analysis of blink rate patterns in normal subjects. Mov Disord. 1997; 12 (6): 1028-1034.
Himebaugh NL, Begley CG, Bradley A, Wilkinson JA. Blinking and tear break-up during four visual tasks. Optom Vis Sci. 2009; 86 (2): E106-114.
Chu CA, Rosenfield M, Portello JK. Blink patterns: reading from a computer screen versus hard copy. Optom Vis Sci. 2014; 91 (3): 297-302.
Argilés M, Cardona G, Pérez-Cabré E, Rodríguez M. Blink rate and incomplete blinks in six different controlled hard-copy and electronic reading conditions. Invest Ophthalmol Vis Sci. 2015; 56 (11): 6679-85.
Rosenfield M, Jahan S, Nunez K, Chan K. Cognitive demand, digital screens and blink rate. Computers Human Behav. 2015; 51A: 403-406.
Jansen ME, Begley CG, Himebaugh NH, Port NL. Effect of contact lens wear and a near task on tear film break-up. Optom Vis Sci. 2010; 87 (5): 350-357.
Portello JK, Rosenfield M, Chu CA. Blink rate, incomplete blinks and computer vision syndrome. Optom Vis Sci. 2013; 90 (5): 482-487.
Yang SN, Tai YC, Sheedy JE, Kinoshita B, Lampa M, Kern JR. Comparative effect of lens care solutions on blink rate, ocular discomfort and visual performance. Ophthalmic Physiol Opt. 2012; 32 (5): 412-20.
Rah MJ, Merchea MM, Doktor MQ. Reducing dropout of contact lens wear with Biotrue multipurpose solution. Clin Ophthalmol. 2014; 8: 293-9.
Jones L. Soft Contact Lens Solutions Review. Part 1: Components of modern care regimens. Optom Pract. 2007; 8 (1): 45–56.
FDA 510 (k) Summary K083757. Bausch & Lomb BPZO2 MultiPurpose Solution. November 18, 2009. Available from: https://www.accessdata.fda.gov/cdrh_docs/pdf8/k083757.pdf. Accessed November 18, 2019.
Reindel W, Cairns G, Merchea M. Assessment of patient and practitioner satisfaction with Biotrue™ multi-purpose solution for contact lenses. Cont Lens Anterior Eye. 2010; 33 (Suppl 1): S12-S17.
Rah MJ, Saxon J, Riendel WT. Real-world performance captures the presbyopic opportunity. Cont Lens Spect. 2016; 31 (13SE): 36-40.
Beusterien K, Tsay S, Gholizadeh S, Su Y. Real-world experience with colorectal cancer chemotherapies: patient web forum analysis. Ecancermedicalscience. 2013; 7: 361.
Boeru G, Milanov I, De Robertis F, et al. ExtaviJect® 30G device for subcutaneous self-injection of interferon beta-1b for multiple sclerosis: a prospective European study. Med Devices (Auckl). 2013; 6: 175-184.
Chaudhuri N, Duck A, Frank R, Holme J, Leonard C. Real world experiences: pirfenidone is well tolerated in patients with idiopathic pulmonary fibrosis. Respir Med. 2014; 108 (1): 224-226.
Ge JB, Zhang F, Qian JY, Ge L, Liu XB, Zhou J. Six-month clinical outcomes of Firebird 2™ sirolimus-eluting stent implantation in real-world patients with coronary artery diseases. Chin Med J (Engl). 2011; 124 (6): 831-835.
Han YL, Chen JY, Xu B, et al. Real world clinical performance of the zotarolimus eluting coronary stent system in Chinese patients: a prospective, multicenter registry study. Chin Med J (Engl). 2011; 124 (20): 3255-3259.
FDA Guidance Document. Use of Real-World Evidence to Support Regulatory Decision-Making for Medical Devices. Guidance for Industry and Food and Drug Administration. August 31, 2017. Available from: https://www.fda.gov/media/99447/download. Accessed November 18, 2019.
Ozdemir M, Temizdemir H. Age- and gender-related tear function changes in normal population. Eye (Lond). 2010; 24 (1): 79-83.
Qiu X, Gong L, Sun X, Jin H. Age-related variations of human tear meniscus and diagnosis of dry eye with Fourier-domain anterior segment optical coherence tomography. Cornea. 2011; 30 (5): 543-9.
Farrand KF, Fridman M, Stillman IÖ, Schaumberg DA. Prevalence of diagnosed dry eye disease in the United States among adults aged 18 years and older. Am J Ophthalmol. 2017; 182: 90-98.
Tonge S, Jones L, Goodall S, Tighe B. The ex vivo wettability of soft contact lenses. Curr Eye Res. 2001; 23 (1): 51-9.
Rah M. A review of hyaluronan and its ophthalmic applications. Optometry. 2011; 82 (1): 38–43.
Fakhari A, Berkland C. Applications and emerging trends of hyaluronic acid in tissue engineering, as a dermal filler and in osteoarthritis treatment. Acta Biomater. 2013; 9 (7): 7081–7092.
Lerner LE, Schwartz DM, Hwang DG, Howes EL, Stern R. Hyaluronan and CD44 in the human cornea and limbal conjunctiva. Exp Eye Res. 1998; 67 (4): 481–484.
Brown MB, Jones SA. Hyaluronic acid: a unique topical vehicle for the localized delivery of drugs to the skin. [J]. Eur Acad Dermatol Venereol. 2005; 19 (3): 308–318.
Laurent TC. Structure of hyaluronic acid. In: Chemistry and Molecular Biology of the Intercellular Matrix (EA Balazs, Ed.). London and New York: Academic Press; 1970: 703-732.
Winter WT, Arnott S. Hyaluronic acid: the role of divalent cations in conformation and packing. [J]. Mol Biol. 1977; 117 (3): 761–784.
Scheuer CA, Doty K, Liranso T, Burke S. Wetting agent retention and release from hydrogel and silicone hydrogel contact lenses. Invest Ophthalmol Vis Sci. 2011; 52: e-abstract 6487. (Poster presented at Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO); 5 May 2011; Fort Lauderdale, Florida, USA.) Available from: https://iovs.arvojournals.org/article.aspx?articleid=2358581. Accessed November 18, 2019.
Scheuer CA, Fridman KM, Barniak VL, Burke SE, Venkatesh S. Retention of conditioning agent hyaluronan on hydrogel contact lenses. Cont Lens Anterior Eye. 2010; 33 (Suppl 1): S2-6.
Scheuer CA, Rah MJ, Reindel WT. Increased concentration of hyaluronan in tears after soaking contact lenses in Biotrue multipurpose solution. Clin Ophthalmol. 2016; 10: 1945-1952.
Fagehi RA, Tomlinson A, Manahilov V. Comparative study of soft contact lens wetting in vitro after storage in Biotrue MPS. Cont Lens Anterior Eye. 2012; 35 (Suppl 1): e21.