Method of preparation and some properties of amorphous cellulose nanoparticles (ANP) have been described in this paper. It was shown that ANP have spherical shape and are characterized by high degree of pantamorphia, low DP and increased content of sulfonic groups. The amorphous nanoparticles of cellulose are completely hydrolyzed by cellulolytic enzymes with forming of glucose. Concentrated paste of ANP has expressed thickening properties and therefore its additive can prevent phase separation of water dispersions of various substances. Low-acidic and soft nanoparticles can be used in cosmetic formulation for gentle skin peeling. Moreover, due to increased content of acidic functional groups, ANP can immobilize various therapeutically-active substances (TAS) containing basic functional groups. The ANP-TAS complexes can be used in remedies aimed for effective care and cure of the skin.
Nanoparticles of Amorphous Cellulose and Their Properties, American Journal of Nano Research and Applications.
Vol. 1, No. 1,
2013, pp. 41-45.
Ch. Hayashi, R. Uyeda, and A. Tasaki, Ultra-fine Particles: Exploratory Science and Technology, Westwood: Noyes Publications, 1997.
M. Ioelovich, "Cellulose as a nanostructured polymer," Bioresources, vol. 3, pp. 1403-1418, 2008.
V.E. Kagan, H. Bayir, and A.A. Shvedova, "Nanomedicine and nanotoxicology: two sides of the same coin," Nanomedicine: nanotechnology, biology and medicine, vol.1, p.313-316, 2005.
C. Buzea, I. Pacheco and K. Robbie, "Nanomaterials and nanoparticles: sources and toxicity," Biointerphases, vol. 2, p.17–71, 2007.
K. Wise and M. Brasuel, "The current state of engineered nanomaterials in consumer goods and waste streams," Nanotech. Sci. Appl., vol.4, pp.73-86, 2011.
V. Alt , T. Bechert, P. Steinrücke, M. Wagener, P. Seidel, E. Dingeldein , E. Domann and R. Schnettler, "An in vitro assessment of the antibacterial properties and cytotoxicity of nanoparticulate silver bone cement," Biomaterials, vol. 25, pp. 4383-4391, 2004.
N. Lewinski, V. Colvin and R. Drezek, "Cytotoxicity of nanoparticles," Small Journal, vol. 4, pp. 26- 49, 2008.
Z. Chen, H. Meng, G. Xing, C. Chen, Y. Zhao, G. Jia, T. Wang, H. Yuan, C. Ye, F. Zhao and Z. Chai, "Acute toxicological affects of copper nanoparticles in vivo," Journal of Physic. Chem, Toxicol. Letters, vol. 163, pp.109-120, 2006.
N. Lu, "Nano titanium dioxide photocatalytic protein tyrosine nitration: a potential hazard of TiO2 on skin," Biochem. Biophys. Res. Commun., vol. 370, pp.675-680, 2008.
K. Donaldson, R. Aitken, L. Tran, V. Stone, R. Duffin, G. Forrest and A. Alexander, "Carbon nanotubes: review of their properties in relation to pulmonary toxicology and workplace safety," Toxicological Science, vol. 92, pp. 5-22, 2006.
J. Jiang, G. Oberdrster, A. Elder, R. Gelein, P. Mercer and P. Biswas, "Does nanoparticle activity depend upon size and crystal phase?" Nanotoxicology, vol. 2, p. 33- 42, 2008.
L. Zhang, F.X. Gu, J.M. Chan, A.Z. Wang, R.S. Lange and O.C. Farokhzad, "Nanoparticles in medicine: therapeutic applications and developments," Clinical Pharma. Therap., vol. 83, pp.761-769, 2008.
M. Ioelovich, O. Figovsky and A. Leykin, "Nanocellulose and its applications," Proceedings of 7th World Congress "Nanocomposite-2007", Las Vegas, USA, 2007.
M. Ioelovich and A. Leykin, "Microcrystalline cellulose: nanostructure formation," Cellulose Chem. Technol., vol.40, pp. 313–317, 2006.
D. Klemm, D. Schumann, F. Kramer, N. Hessler, M. Hornung, H-P. Schmauder and S.Marsch, "Nanocelluloses as innovative polymers in research and application," Adv. Polymer Sci., vol. 205, pp.49-96, 2006.
M. A. Hubbe, O.J. Rojas, L.A. Lucia and M. Sain, "Cellulosic nanocomposites – a review," Bioresources 3(3), pp. 929-980, 2008.
Y. Habibi, L. A. Lucia and O. J. Rojas, "Cellulose nanocrystals: chemistry, self-assembly, and applications," Chemical Reviews, vol. 110, pp. 3479–3500, 2010.
Y. Li and A. Ragauskas, "Cellulose nano-whiskers as a reinforcing filler in polyurethanes," Advances in Diverse Industrial Applications of Nanocomposites, vol. 3, pp. 17–36, 2011.
I. Siro and D. Plakett, "Microfibrillated cellulose and new composite materials," Cellulose, vol. 17, pp.459-494, 2010.
M. Ioelovich, "Study of cellulose interaction with concentrated solutions of sulfuric acid," ISRN Chem. Eng., vol. 2012, pp. 1-7, 2012.
M. Ioelovich, "Optimal conditions for isolation of nanocrystalline cellulose particles," Nanosci. Nanotech., vol.2, pp.9-13 , 2012.
M. Ioelovich, A. Leykin and O. Figovsky, "Study of cellulose paracrystallinity," Bioresources, vol. 5, pp. 1393–1407, 2010.
F. Camacho, P. Gonzalez-Tello, E. Jurado and A. Robles, "Microcrystalline cellulose hydrolysis with concentrated sulphuric acid," Journal Chem. Technol. Biotechnol., vol. 67, pp. 350–356, 1996.