Comparison of the Antiparasitic Activity of <i>Bauhinia rufescens</i> Leaves Extracts and Metronidazole Against <i>Gairdia lamblia</i>

Mohamed Ismail Garbi; Elbadri Elamin Osman; Ahmed Saeed Kabbashi

doi:doi:10.11648/j.bio.20170505.12

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Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia

Mohamed Ismail Garbi, Elbadri Elamin Osman, Ahmed Saeed Kabbashi

Published in American Journal of Bioscience and Bioengineering (Volume 5, Issue 5)

Received: 4 October 2017 Accepted: 26 October 2017 Published: 22 November 2017

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Abstract

Giardia is a flagellate protozoan with worldwide distribution that causes significant gastrointestinal diseases in a wide variety of vertebrates including cats and human. Gairdia lamblia is one of the intestinal protozoa that cause public health problems in most developing countries as well as some developed countries. This study was carried out to evaluate Antigiardial activity of Bauhinia rufsescens (Leaves) petroleum ether and methanolic extracts in vitro test were perform using four concentrations: (1000, 500, 250 and 125 ppm). The highest activity against G. lameblia with respect to time was obtained from petroleum ether extract which exhibited 77.12% mortality within 72 h in 1000 ppm concentration, followed by the same extract which exhibited 76.04% mortality within 72 h with concentration of 500 ppm. On the other hand, the lowest antigiardial activity was recorded by B. rufescens petroleum ether extract 82.8% mortality with 125 ppm concentration within 24 hours, with whereas Metronidazol, a pure compound (positive control) showed 83.42% mortality within 72 hours. This result shows that the most potent antigiardial activity was demonstrated in B. rufescens petroleum ether extract at all concentrations (i.e. 74% mortality within 72 hours) and that B. rufescens species, as claimed also by tradition, is a promising species in treating G. lamblia.

Published in	American Journal of Bioscience and Bioengineering (Volume 5, Issue 5)
DOI	10.11648/j.bio.20170505.12
Page(s)	104-108
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Bauhinia rufescens, Gairdia lameblia, Metronidazol

References

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APA Style

Mohamed Ismail Garbi, Elbadri Elamin Osman, Ahmed Saeed Kabbashi. (2017). Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia. American Journal of Bioscience and Bioengineering, 5(5), 104-108. https://doi.org/10.11648/j.bio.20170505.12

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ACS Style

Mohamed Ismail Garbi; Elbadri Elamin Osman; Ahmed Saeed Kabbashi. Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia. Am. J. BioSci. Bioeng. 2017, 5(5), 104-108. doi: 10.11648/j.bio.20170505.12

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AMA Style

Mohamed Ismail Garbi, Elbadri Elamin Osman, Ahmed Saeed Kabbashi. Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia. Am J BioSci Bioeng. 2017;5(5):104-108. doi: 10.11648/j.bio.20170505.12

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@article{10.11648/j.bio.20170505.12,
  author = {Mohamed Ismail Garbi and Elbadri Elamin Osman and Ahmed Saeed Kabbashi},
  title = {Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia},
  journal = {American Journal of Bioscience and Bioengineering},
  volume = {5},
  number = {5},
  pages = {104-108},
  doi = {10.11648/j.bio.20170505.12},
  url = {https://doi.org/10.11648/j.bio.20170505.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20170505.12},
  abstract = {Giardia is a flagellate protozoan with worldwide distribution that causes significant gastrointestinal diseases in a wide variety of vertebrates including cats and human. Gairdia lamblia is one of the intestinal protozoa that cause public health problems in most developing countries as well as some developed countries. This study was carried out to evaluate Antigiardial activity of Bauhinia rufsescens (Leaves) petroleum ether and methanolic extracts in vitro test were perform using four concentrations: (1000, 500, 250 and 125 ppm). The highest activity against G. lameblia with respect to time was obtained from petroleum ether extract which exhibited 77.12% mortality within 72 h in 1000 ppm concentration, followed by the same extract which exhibited 76.04% mortality within 72 h with concentration of 500 ppm. On the other hand, the lowest antigiardial activity was recorded by B. rufescens petroleum ether extract 82.8% mortality with 125 ppm concentration within 24 hours, with whereas Metronidazol, a pure compound (positive control) showed 83.42% mortality within 72 hours. This result shows that the most potent antigiardial activity was demonstrated in B. rufescens petroleum ether extract at all concentrations (i.e. 74% mortality within 72 hours) and that B. rufescens species, as claimed also by tradition, is a promising species in treating G. lamblia.},
 year = {2017}
}

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TY - JOUR
T1 - Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia
AU - Mohamed Ismail Garbi
AU - Elbadri Elamin Osman
AU - Ahmed Saeed Kabbashi
Y1 - 2017/11/22
PY - 2017
N1 - https://doi.org/10.11648/j.bio.20170505.12
DO - 10.11648/j.bio.20170505.12
T2 - American Journal of Bioscience and Bioengineering
JF - American Journal of Bioscience and Bioengineering
JO - American Journal of Bioscience and Bioengineering
SP - 104
EP - 108
PB - Science Publishing Group
SN - 2328-5893
UR - https://doi.org/10.11648/j.bio.20170505.12
AB - Giardia is a flagellate protozoan with worldwide distribution that causes significant gastrointestinal diseases in a wide variety of vertebrates including cats and human. Gairdia lamblia is one of the intestinal protozoa that cause public health problems in most developing countries as well as some developed countries. This study was carried out to evaluate Antigiardial activity of Bauhinia rufsescens (Leaves) petroleum ether and methanolic extracts in vitro test were perform using four concentrations: (1000, 500, 250 and 125 ppm). The highest activity against G. lameblia with respect to time was obtained from petroleum ether extract which exhibited 77.12% mortality within 72 h in 1000 ppm concentration, followed by the same extract which exhibited 76.04% mortality within 72 h with concentration of 500 ppm. On the other hand, the lowest antigiardial activity was recorded by B. rufescens petroleum ether extract 82.8% mortality with 125 ppm concentration within 24 hours, with whereas Metronidazol, a pure compound (positive control) showed 83.42% mortality within 72 hours. This result shows that the most potent antigiardial activity was demonstrated in B. rufescens petroleum ether extract at all concentrations (i.e. 74% mortality within 72 hours) and that B. rufescens species, as claimed also by tradition, is a promising species in treating G. lamblia.
VL - 5
IS - 5
ER -

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Author Information

Mohamed Ismail Garbi

Department of Microbiology and Parasitology, Faculty of Medical Laboratory Sciences, Ibn Sina University, Khartoum, Sudan
Elbadri Elamin Osman

Department of Microbiology, Faculty of Pure and Applied Sciences, International University of Africa, Khartoum, Sudan
Ahmed Saeed Kabbashi

Department of Microbiology, Faculty of Medical Laboratory Sciences, International University of Africa, Khartoum, Sudan

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APA Style

Mohamed Ismail Garbi, Elbadri Elamin Osman, Ahmed Saeed Kabbashi. (2017). Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia. American Journal of Bioscience and Bioengineering, 5(5), 104-108. https://doi.org/10.11648/j.bio.20170505.12

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ACS Style

Mohamed Ismail Garbi; Elbadri Elamin Osman; Ahmed Saeed Kabbashi. Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia. Am. J. BioSci. Bioeng. 2017, 5(5), 104-108. doi: 10.11648/j.bio.20170505.12

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AMA Style

Mohamed Ismail Garbi, Elbadri Elamin Osman, Ahmed Saeed Kabbashi. Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia. Am J BioSci Bioeng. 2017;5(5):104-108. doi: 10.11648/j.bio.20170505.12

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@article{10.11648/j.bio.20170505.12,
  author = {Mohamed Ismail Garbi and Elbadri Elamin Osman and Ahmed Saeed Kabbashi},
  title = {Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia},
  journal = {American Journal of Bioscience and Bioengineering},
  volume = {5},
  number = {5},
  pages = {104-108},
  doi = {10.11648/j.bio.20170505.12},
  url = {https://doi.org/10.11648/j.bio.20170505.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20170505.12},
  abstract = {Giardia is a flagellate protozoan with worldwide distribution that causes significant gastrointestinal diseases in a wide variety of vertebrates including cats and human. Gairdia lamblia is one of the intestinal protozoa that cause public health problems in most developing countries as well as some developed countries. This study was carried out to evaluate Antigiardial activity of Bauhinia rufsescens (Leaves) petroleum ether and methanolic extracts in vitro test were perform using four concentrations: (1000, 500, 250 and 125 ppm). The highest activity against G. lameblia with respect to time was obtained from petroleum ether extract which exhibited 77.12% mortality within 72 h in 1000 ppm concentration, followed by the same extract which exhibited 76.04% mortality within 72 h with concentration of 500 ppm. On the other hand, the lowest antigiardial activity was recorded by B. rufescens petroleum ether extract 82.8% mortality with 125 ppm concentration within 24 hours, with whereas Metronidazol, a pure compound (positive control) showed 83.42% mortality within 72 hours. This result shows that the most potent antigiardial activity was demonstrated in B. rufescens petroleum ether extract at all concentrations (i.e. 74% mortality within 72 hours) and that B. rufescens species, as claimed also by tradition, is a promising species in treating G. lamblia.},
 year = {2017}
}

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