Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle

Arenas-Ríos Edith; Rosado Adolfo; Rodríguez-Tobón Ernesto; Rodríguez-Tobón Ahiezer; León-Galván Miguel Ángel

doi:doi:10.11648/j.avs.s.2015030101.12

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Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle

Arenas-Ríos Edith, Rosado Adolfo, Rodríguez-Tobón Ernesto, Rodríguez-Tobón Ahiezer, León-Galván Miguel Ángel

Published in Animal and Veterinary Sciences (Volume 3, Issue 1-1)

Received: 28 January 2015 Accepted: 29 January 2015 Published: 27 February 2015

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Abstract

GGT initiates the degradation of both oxidized and reduced glutathione at the cell surface by cleaving the unique gamma glutamyl bond. The successive hydrolysis of oxidized or reduced CysGly by aminopeptidase or dipeptidase releases Gly, and cysteine/cysteine is recovered for intracellular synthesis of glutathione. In addition, GGT plays a major physiological role in providing cysteine to cells for GSH synthesis and protein synthesis, thereby playing a major role in antioxidant defense and normal growth. GGT is present in the epididymis, principally in caput. The catalytic activity of GGT is highest in the proximal epididymal regions and decreases toward the distal regions; participating in the epididymal sperm maturation process.In most mammals, epididymal sperm maturation takes place in a period not exceeding ten days, ending in the distal part of the corpus of the epididymis, before reaching the caudal region, which is responsible only for sperm storage; however, in C. mexicanus the epididymal sperm maturation ends in caudal epididymalregion.For this reason, the main goal of the present study was to determine the relationship between the GGT activity through the caput and caudal epididymal regions, throughout annual cycle of Corynorhinusmexicanus bat.We found that the GGT activity appears to be important for epididymal sperm maturation in C. mexicanus bat in cephalic region, and important for protection against ROS epididymal caudal region.

Published in	Animal and Veterinary Sciences (Volume 3, Issue 1-1) This article belongs to the Special Issue Advances in Bat’s Reproduction
DOI	10.11648/j.avs.s.2015030101.12
Page(s)	8-12
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Bats, Gamma GlutamylTranspeptidase, Epididymis, Sperm Maturation, Glutathione

References

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APA Style

Arenas-Ríos Edith, Rosado Adolfo, Rodríguez-Tobón Ernesto, Rodríguez-Tobón Ahiezer, León-Galván Miguel Ángel. (2015). Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle. Animal and Veterinary Sciences, 3(1-1), 8-12. https://doi.org/10.11648/j.avs.s.2015030101.12

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ACS Style

Arenas-Ríos Edith; Rosado Adolfo; Rodríguez-Tobón Ernesto; Rodríguez-Tobón Ahiezer; León-Galván Miguel Ángel. Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle. Anim. Vet. Sci. 2015, 3(1-1), 8-12. doi: 10.11648/j.avs.s.2015030101.12

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AMA Style

Arenas-Ríos Edith, Rosado Adolfo, Rodríguez-Tobón Ernesto, Rodríguez-Tobón Ahiezer, León-Galván Miguel Ángel. Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle. Anim Vet Sci. 2015;3(1-1):8-12. doi: 10.11648/j.avs.s.2015030101.12

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@article{10.11648/j.avs.s.2015030101.12,
  author = {Arenas-Ríos Edith and Rosado Adolfo and Rodríguez-Tobón Ernesto and Rodríguez-Tobón Ahiezer and León-Galván Miguel Ángel},
  title = {Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle},
  journal = {Animal and Veterinary Sciences},
  volume = {3},
  number = {1-1},
  pages = {8-12},
  doi = {10.11648/j.avs.s.2015030101.12},
  url = {https://doi.org/10.11648/j.avs.s.2015030101.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.s.2015030101.12},
  abstract = {GGT initiates the degradation of both oxidized and reduced glutathione at the cell surface by cleaving the unique gamma glutamyl bond. The successive hydrolysis of oxidized or reduced CysGly by aminopeptidase or dipeptidase releases Gly, and cysteine/cysteine is recovered for intracellular synthesis of glutathione. In addition, GGT plays a major physiological role in providing cysteine to cells for GSH synthesis and protein synthesis, thereby playing a major role in antioxidant defense and normal growth. GGT is present in the epididymis, principally in caput. The catalytic activity of GGT is highest in the proximal epididymal regions and decreases toward the distal regions; participating in the epididymal sperm maturation process.In most mammals, epididymal sperm maturation takes place in a period not exceeding ten days, ending in the distal part of the corpus of the epididymis, before reaching the caudal region, which is responsible only for sperm storage; however, in C. mexicanus the epididymal sperm maturation ends in caudal epididymalregion.For this reason, the main goal of the present study was to determine the relationship between the GGT activity through the caput and caudal epididymal regions, throughout annual cycle of Corynorhinusmexicanus bat.We found that the GGT activity appears to be important for epididymal sperm maturation in C. mexicanus bat in cephalic region, and important for protection against ROS epididymal caudal region.},
 year = {2015}
}

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TY  - JOUR
T1  - Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle
AU  - Arenas-Ríos Edith
AU  - Rosado Adolfo
AU  - Rodríguez-Tobón Ernesto
AU  - Rodríguez-Tobón Ahiezer
AU  - León-Galván Miguel Ángel
Y1  - 2015/02/27
PY  - 2015
N1  - https://doi.org/10.11648/j.avs.s.2015030101.12
DO  - 10.11648/j.avs.s.2015030101.12
T2  - Animal and Veterinary Sciences
JF  - Animal and Veterinary Sciences
JO  - Animal and Veterinary Sciences
SP  - 8
EP  - 12
PB  - Science Publishing Group
SN  - 2328-5850
UR  - https://doi.org/10.11648/j.avs.s.2015030101.12
AB  - GGT initiates the degradation of both oxidized and reduced glutathione at the cell surface by cleaving the unique gamma glutamyl bond. The successive hydrolysis of oxidized or reduced CysGly by aminopeptidase or dipeptidase releases Gly, and cysteine/cysteine is recovered for intracellular synthesis of glutathione. In addition, GGT plays a major physiological role in providing cysteine to cells for GSH synthesis and protein synthesis, thereby playing a major role in antioxidant defense and normal growth. GGT is present in the epididymis, principally in caput. The catalytic activity of GGT is highest in the proximal epididymal regions and decreases toward the distal regions; participating in the epididymal sperm maturation process.In most mammals, epididymal sperm maturation takes place in a period not exceeding ten days, ending in the distal part of the corpus of the epididymis, before reaching the caudal region, which is responsible only for sperm storage; however, in C. mexicanus the epididymal sperm maturation ends in caudal epididymalregion.For this reason, the main goal of the present study was to determine the relationship between the GGT activity through the caput and caudal epididymal regions, throughout annual cycle of Corynorhinusmexicanus bat.We found that the GGT activity appears to be important for epididymal sperm maturation in C. mexicanus bat in cephalic region, and important for protection against ROS epididymal caudal region.
VL  - 3
IS  - 1-1
ER  -

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Author Information

Arenas-Ríos Edith

Department of Biology of Reproduction, Autonomous Metropolitan University–Iztapalapa, Iztapalapa,México
Rosado Adolfo

Department of Biology of Reproduction, Autonomous Metropolitan University–Iztapalapa, Iztapalapa,México
Rodríguez-Tobón Ernesto

Masters in Biology of Reproduction ,Autonomous Metropolitan University–Iztapalapa, Iztapalapa,México
Rodríguez-Tobón Ahiezer

PhD in Experimental Biology, Autonomous Metropolitan University–Iztapalapa, Iztapalapa,México
León-Galván Miguel Ángel

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APA Style

Arenas-Ríos Edith, Rosado Adolfo, Rodríguez-Tobón Ernesto, Rodríguez-Tobón Ahiezer, León-Galván Miguel Ángel. (2015). Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle. Animal and Veterinary Sciences, 3(1-1), 8-12. https://doi.org/10.11648/j.avs.s.2015030101.12

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ACS Style

Arenas-Ríos Edith; Rosado Adolfo; Rodríguez-Tobón Ernesto; Rodríguez-Tobón Ahiezer; León-Galván Miguel Ángel. Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle. Anim. Vet. Sci. 2015, 3(1-1), 8-12. doi: 10.11648/j.avs.s.2015030101.12

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AMA Style

Arenas-Ríos Edith, Rosado Adolfo, Rodríguez-Tobón Ernesto, Rodríguez-Tobón Ahiezer, León-Galván Miguel Ángel. Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle. Anim Vet Sci. 2015;3(1-1):8-12. doi: 10.11648/j.avs.s.2015030101.12

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@article{10.11648/j.avs.s.2015030101.12,
  author = {Arenas-Ríos Edith and Rosado Adolfo and Rodríguez-Tobón Ernesto and Rodríguez-Tobón Ahiezer and León-Galván Miguel Ángel},
  title = {Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle},
  journal = {Animal and Veterinary Sciences},
  volume = {3},
  number = {1-1},
  pages = {8-12},
  doi = {10.11648/j.avs.s.2015030101.12},
  url = {https://doi.org/10.11648/j.avs.s.2015030101.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.s.2015030101.12},
  abstract = {GGT initiates the degradation of both oxidized and reduced glutathione at the cell surface by cleaving the unique gamma glutamyl bond. The successive hydrolysis of oxidized or reduced CysGly by aminopeptidase or dipeptidase releases Gly, and cysteine/cysteine is recovered for intracellular synthesis of glutathione. In addition, GGT plays a major physiological role in providing cysteine to cells for GSH synthesis and protein synthesis, thereby playing a major role in antioxidant defense and normal growth. GGT is present in the epididymis, principally in caput. The catalytic activity of GGT is highest in the proximal epididymal regions and decreases toward the distal regions; participating in the epididymal sperm maturation process.In most mammals, epididymal sperm maturation takes place in a period not exceeding ten days, ending in the distal part of the corpus of the epididymis, before reaching the caudal region, which is responsible only for sperm storage; however, in C. mexicanus the epididymal sperm maturation ends in caudal epididymalregion.For this reason, the main goal of the present study was to determine the relationship between the GGT activity through the caput and caudal epididymal regions, throughout annual cycle of Corynorhinusmexicanus bat.We found that the GGT activity appears to be important for epididymal sperm maturation in C. mexicanus bat in cephalic region, and important for protection against ROS epididymal caudal region.},
 year = {2015}
}

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TY  - JOUR
T1  - Gamma GlutamylTranspeptidase Activity Determination in Epididymis of Corynorhinusmexicanus Bat Throughout Its Annual Cycle
AU  - Arenas-Ríos Edith
AU  - Rosado Adolfo
AU  - Rodríguez-Tobón Ernesto
AU  - Rodríguez-Tobón Ahiezer
AU  - León-Galván Miguel Ángel
Y1  - 2015/02/27
PY  - 2015
N1  - https://doi.org/10.11648/j.avs.s.2015030101.12
DO  - 10.11648/j.avs.s.2015030101.12
T2  - Animal and Veterinary Sciences
JF  - Animal and Veterinary Sciences
JO  - Animal and Veterinary Sciences
SP  - 8
EP  - 12
PB  - Science Publishing Group
SN  - 2328-5850
UR  - https://doi.org/10.11648/j.avs.s.2015030101.12
AB  - GGT initiates the degradation of both oxidized and reduced glutathione at the cell surface by cleaving the unique gamma glutamyl bond. The successive hydrolysis of oxidized or reduced CysGly by aminopeptidase or dipeptidase releases Gly, and cysteine/cysteine is recovered for intracellular synthesis of glutathione. In addition, GGT plays a major physiological role in providing cysteine to cells for GSH synthesis and protein synthesis, thereby playing a major role in antioxidant defense and normal growth. GGT is present in the epididymis, principally in caput. The catalytic activity of GGT is highest in the proximal epididymal regions and decreases toward the distal regions; participating in the epididymal sperm maturation process.In most mammals, epididymal sperm maturation takes place in a period not exceeding ten days, ending in the distal part of the corpus of the epididymis, before reaching the caudal region, which is responsible only for sperm storage; however, in C. mexicanus the epididymal sperm maturation ends in caudal epididymalregion.For this reason, the main goal of the present study was to determine the relationship between the GGT activity through the caput and caudal epididymal regions, throughout annual cycle of Corynorhinusmexicanus bat.We found that the GGT activity appears to be important for epididymal sperm maturation in C. mexicanus bat in cephalic region, and important for protection against ROS epididymal caudal region.
VL  - 3
IS  - 1-1
ER  -

Copy | Download