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Whitening Efficacy Evaluation of the Multi-Herb

Received: 9 August 2018     Published: 10 August 2018
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Abstract

The multi-Herb (mH) was prepared from 4 plant extracts including Phyllostachis Bambusoides, Sophora Flavescens Root, Lycium Barbarum Fruit and Pyracantha Fortuneana Fruit through ethanol extraction, filtration and concentration. Focus on tyrosinase activity and melanin content, mH repressed the activity of tyrosinase from mushroom and B16F1 cells to 49.2% and 76.2% respectively, at concentration of 3%. mH reduced the cellular melanin synthesis to 98.2% in nature and 92.1% under α-MSH induced melanogenesis respectively, showed a dose-dependently inhibitory effect. The human-skin test results showed that the skin melanin content (MI value) was significantly reduced by 12.3% after 7 weeks application of a cream containing 5% mH, better than arbutin of 2% concentration. All the results indicate that mH displays a good effect for whitening.

Published in Science Discovery (Volume 6, Issue 4)
DOI 10.11648/j.sd.20180604.22
Page(s) 306-311
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Multi-Herb, Tyrosinase, Melanin Synthesis, Human-Skin Test

References
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  • APA Style

    Lu Yi-na, Yang Ya-di, Lin Meng-gan, Xie Zhi-yong. (2018). Whitening Efficacy Evaluation of the Multi-Herb. Science Discovery, 6(4), 306-311. https://doi.org/10.11648/j.sd.20180604.22

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    ACS Style

    Lu Yi-na; Yang Ya-di; Lin Meng-gan; Xie Zhi-yong. Whitening Efficacy Evaluation of the Multi-Herb. Sci. Discov. 2018, 6(4), 306-311. doi: 10.11648/j.sd.20180604.22

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    AMA Style

    Lu Yi-na, Yang Ya-di, Lin Meng-gan, Xie Zhi-yong. Whitening Efficacy Evaluation of the Multi-Herb. Sci Discov. 2018;6(4):306-311. doi: 10.11648/j.sd.20180604.22

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  • @article{10.11648/j.sd.20180604.22,
      author = {Lu Yi-na and Yang Ya-di and Lin Meng-gan and Xie Zhi-yong},
      title = {Whitening Efficacy Evaluation of the Multi-Herb},
      journal = {Science Discovery},
      volume = {6},
      number = {4},
      pages = {306-311},
      doi = {10.11648/j.sd.20180604.22},
      url = {https://doi.org/10.11648/j.sd.20180604.22},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20180604.22},
      abstract = {The multi-Herb (mH) was prepared from 4 plant extracts including Phyllostachis Bambusoides, Sophora Flavescens Root, Lycium Barbarum Fruit and Pyracantha Fortuneana Fruit through ethanol extraction, filtration and concentration. Focus on tyrosinase activity and melanin content, mH repressed the activity of tyrosinase from mushroom and B16F1 cells to 49.2% and 76.2% respectively, at concentration of 3%. mH reduced the cellular melanin synthesis to 98.2% in nature and 92.1% under α-MSH induced melanogenesis respectively, showed a dose-dependently inhibitory effect. The human-skin test results showed that the skin melanin content (MI value) was significantly reduced by 12.3% after 7 weeks application of a cream containing 5% mH, better than arbutin of 2% concentration. All the results indicate that mH displays a good effect for whitening.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - Whitening Efficacy Evaluation of the Multi-Herb
    AU  - Lu Yi-na
    AU  - Yang Ya-di
    AU  - Lin Meng-gan
    AU  - Xie Zhi-yong
    Y1  - 2018/08/10
    PY  - 2018
    N1  - https://doi.org/10.11648/j.sd.20180604.22
    DO  - 10.11648/j.sd.20180604.22
    T2  - Science Discovery
    JF  - Science Discovery
    JO  - Science Discovery
    SP  - 306
    EP  - 311
    PB  - Science Publishing Group
    SN  - 2331-0650
    UR  - https://doi.org/10.11648/j.sd.20180604.22
    AB  - The multi-Herb (mH) was prepared from 4 plant extracts including Phyllostachis Bambusoides, Sophora Flavescens Root, Lycium Barbarum Fruit and Pyracantha Fortuneana Fruit through ethanol extraction, filtration and concentration. Focus on tyrosinase activity and melanin content, mH repressed the activity of tyrosinase from mushroom and B16F1 cells to 49.2% and 76.2% respectively, at concentration of 3%. mH reduced the cellular melanin synthesis to 98.2% in nature and 92.1% under α-MSH induced melanogenesis respectively, showed a dose-dependently inhibitory effect. The human-skin test results showed that the skin melanin content (MI value) was significantly reduced by 12.3% after 7 weeks application of a cream containing 5% mH, better than arbutin of 2% concentration. All the results indicate that mH displays a good effect for whitening.
    VL  - 6
    IS  - 4
    ER  - 

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Author Information
  • Shanghai Greaf Biotech Co. Ltd., Shanghai, China

  • Shanghai Greaf Biotech Co. Ltd., Shanghai, China

  • Shanghai Greaf Biotech Co. Ltd., Shanghai, China

  • Shanghai Greaf Biotech Co. Ltd., Shanghai, China

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