Neuroimaging Insights Pertaining to Physical Activity Effects upon Brain Structure in Mild Cognitive Impairment and in Alzheimer’s Disease
International Journal of Psychological and Brain Sciences
Volume 3, Issue 3, June 2018, Pages: 22-32
Received: Jun. 3, 2018; Accepted: Jun. 21, 2018; Published: Jul. 11, 2018
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Youshan Zhang, Department of Computer Science and Engineering, Lehigh University, Bethlehem, USA
Nicole Marcione, Department of Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, USA
Danielle Borrajo, Department of Neuroimaging and Informatics, University of Southern California, Los Angeles, USA
Julia Boudreau, Department of Neuroimaging and Informatics, University of Southern California, Los Angeles, USA
Neda Khanjani, Department of Neuroimaging and Informatics, University of Southern California, Los Angeles, USA
Yujia Zhong, Department of Neuroimaging and Informatics, University of Southern California, Los Angeles, USA
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Alzheimer’s disease (AD) and mild cognitive impairments (MCI) are two neurological conditions that commonly affect the aging brain. These conditions cause debilitating symptoms, namely, the loss of the ability to perform activities of daily living. This prevents the patient from being able to live independently and severely decreases their quality of life. A growing treatment option involves the patient integrating physical activity (PA) into their daily lives. There is an increasing amount of evidence that supports both the psychological and anatomical improvements of MCI and AD patients that engage in PA. The different cognitive improvements measured via neuropsychological assessments complement the neuroimaging data found in current literature. Different neuroimaging modalities such as PET, MRI, fMRI and EEG all contribute to the amount of data in support of PA as a viable treatment option for people with AD and MCI. Notable improvements can be found in the hippocampal region of the brain. Other lifestyle advancements such as diet changes and sleeping habits can also have a profound effect on AD and MCI patients. Our research is important because it will lead to treatments that can delay the onset of these diseases or even aid in finding an ultimate cure.
Alzheimer’s Disease, Mild Cognitive Impairment, Physical Activity, Neuroimaging
To cite this article
Youshan Zhang, Nicole Marcione, Danielle Borrajo, Julia Boudreau, Neda Khanjani, Yujia Zhong, Neuroimaging Insights Pertaining to Physical Activity Effects upon Brain Structure in Mild Cognitive Impairment and in Alzheimer’s Disease, International Journal of Psychological and Brain Sciences. Vol. 3, No. 3, 2018, pp. 22-32. doi: 10.11648/j.ijpbs.20180303.11
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