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Determination of Beta Radiation Dose to the Thyroid Gland from the Ingestion of 131I by Patients

Received: 11 May 2016    Accepted: 12 December 2016    Published: 9 January 2017
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Abstract

Total activities due to the ingestion of 131I were evaluated in different compartments of the human body of patients. It has been shown that the 131I activity in urine of patients increases when the 131I uptake decreases which could represent a source of radiation for their relatives when they leave hospitals. A new dosimetric model based on the specific beta-dose concept was developed for evaluating committed equivalent doses to thyroid due to 131I uptake by different age groups of patients. Data obtained are in good agreement with those obtained by using the ICRP model for iodine. Committed equivalent dose to the thyroid gland is influenced by the mass of thyroid, 131I uptake and energy of the emitted beta particles. In addition, 131I uptake was measured by using a gamma camera and committed equivalent doses to the thyroid gland of female patients from the ingestion of 131I for the treatment of hyperthyroidism diseases were evaluated. Data obtained by using our model and the ICRP ingestion dose coefficients are in good agreement with each other.

Published in American Journal of Environmental Protection (Volume 5, Issue 6)
DOI 10.11648/j.ajep.20160506.14
Page(s) 168-178
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

131I Uptake, Thyroid Gland, Hyperthyroidism Disease, Beta Dose Assessment

References
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[2] International Commission on Radiological Protection, Nuclear decay data for dosimetric calculations, ICRP Publication 107, Ann ICRP 38 (3), 2008.
[3] P. Hall, A. Mattisson, J. D. Boice Jr, “Thyroid cancer after diagnostic administration of iodine-131”. Rad. Reas., 1996, Vol. 145, pp 86-92.
[4] J. C. Sisson, J. Freitas, I. R. McDougall et al., “Radiation safety in the treatment of patients with thyroid diseases by radioiodine 131I”, Practice recommendations of the American thyroid Association, Thyroid, 2011, Vol. 21, pp 335-346.
[5] A. Wiszomirska, “Iodine-131 for therapy of thyroid diseases, Physical and biological basis”, Nul. Med. R., 2012, Vol. 15, pp 120-123.
[6] A. Vaiano, A. Claudio Traino, G. Boni et al., “Comparison between remnant and red-marrow absorbed dose in thyroid cancer patients submitted to 131I ablative therapy after rh-TSH simulation versus hypothyroidism induced by L-thyroxine withdrawal”, Nucl. Med. Commun., 2007, Vol. 28, pp 215-223.
[7] B. M. Dantas, F. F. Lima, A. L. Dantas et al., “Determination of uncertainties associated to the in vivo measurement of iodine-131 in the thyroid”, Appl. Radiat. Isot., 2016, Vol. 113, pp 1-4.
[8] D. Bernard, M. D. Desruet, M. Wolf et al., “Radioiodine therapy in benign thyroid disorders. Evaluation of French nuclear medicine practices”, Ann. Endocr., 2014, Vol. 75 (4), pp 241-246.
[9] I. Al-Shammeri, S. Al-Deen Mahmood, S. Al-Mohannadi et al., “Clinical experience of 2-hour I-131 thyroid uptake significance in considering the radioiodine Graves’ disease treatment dose: A retrospective study”, Radiogr., 2015, Vol. 21 (3), pp 254-257.
[10] T. Cappelen, J. F. Unhjem, A. L. Amundsen et al., “Radiation exposure to family members of patients with thyrotoxicosis treated with iodine-131”, Eur. J. Nucl. Med. Mol. I, 2006, Vol. 33, pp 81-86.
[11] International commission on Radiological Protection, Age-dependent doses to members of the public from intakes of radionuclides: Part 1, ICRP Publication 56, Ann. ICRP 20 (2), 1989.
[12] Waterloo Maple Software, Maple Version 8.0, 2002.
[13] International commission on Radiological Protection, Recommendations of the International Commission on Radiological Protection, ICRP Publication 103, Ann ICRP 37 (2-4), 2007.
[14] M. J. Berger, J. S. Coursey, M. A. Zukcer, et al., ESTAR, PSTAR, and ASTAR, “Computer programs for calculating stopping –power and range tables for electrons, protons, and helium ions”, Version 1.2.3, 2005.
[15] International commission on Radiological Protection, Basic anatomical and physiological data for use in radiological protection, ICRP Publication 89, Ann ICRP 32 (3/4), 2002.
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  • APA Style

    M. A. Misdaq, H. Harrass, M. Karime, A. Matrane. (2017). Determination of Beta Radiation Dose to the Thyroid Gland from the Ingestion of 131I by Patients. American Journal of Environmental Protection, 5(6), 168-178. https://doi.org/10.11648/j.ajep.20160506.14

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    ACS Style

    M. A. Misdaq; H. Harrass; M. Karime; A. Matrane. Determination of Beta Radiation Dose to the Thyroid Gland from the Ingestion of 131I by Patients. Am. J. Environ. Prot. 2017, 5(6), 168-178. doi: 10.11648/j.ajep.20160506.14

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    AMA Style

    M. A. Misdaq, H. Harrass, M. Karime, A. Matrane. Determination of Beta Radiation Dose to the Thyroid Gland from the Ingestion of 131I by Patients. Am J Environ Prot. 2017;5(6):168-178. doi: 10.11648/j.ajep.20160506.14

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  • @article{10.11648/j.ajep.20160506.14,
      author = {M. A. Misdaq and H. Harrass and M. Karime and A. Matrane},
      title = {Determination of Beta Radiation Dose to the Thyroid Gland from the Ingestion of 131I by Patients},
      journal = {American Journal of Environmental Protection},
      volume = {5},
      number = {6},
      pages = {168-178},
      doi = {10.11648/j.ajep.20160506.14},
      url = {https://doi.org/10.11648/j.ajep.20160506.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajep.20160506.14},
      abstract = {Total activities due to the ingestion of 131I were evaluated in different compartments of the human body of patients. It has been shown that the 131I activity in urine of patients increases when the 131I uptake decreases which could represent a source of radiation for their relatives when they leave hospitals. A new dosimetric model based on the specific beta-dose concept was developed for evaluating committed equivalent doses to thyroid due to 131I uptake by different age groups of patients. Data obtained are in good agreement with those obtained by using the ICRP model for iodine. Committed equivalent dose to the thyroid gland is influenced by the mass of thyroid, 131I uptake and energy of the emitted beta particles. In addition, 131I uptake was measured by using a gamma camera and committed equivalent doses to the thyroid gland of female patients from the ingestion of 131I for the treatment of hyperthyroidism diseases were evaluated. Data obtained by using our model and the ICRP ingestion dose coefficients are in good agreement with each other.},
     year = {2017}
    }
    

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    AB  - Total activities due to the ingestion of 131I were evaluated in different compartments of the human body of patients. It has been shown that the 131I activity in urine of patients increases when the 131I uptake decreases which could represent a source of radiation for their relatives when they leave hospitals. A new dosimetric model based on the specific beta-dose concept was developed for evaluating committed equivalent doses to thyroid due to 131I uptake by different age groups of patients. Data obtained are in good agreement with those obtained by using the ICRP model for iodine. Committed equivalent dose to the thyroid gland is influenced by the mass of thyroid, 131I uptake and energy of the emitted beta particles. In addition, 131I uptake was measured by using a gamma camera and committed equivalent doses to the thyroid gland of female patients from the ingestion of 131I for the treatment of hyperthyroidism diseases were evaluated. Data obtained by using our model and the ICRP ingestion dose coefficients are in good agreement with each other.
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Author Information
  • Nuclear Physics and Techniques Laboratory, Faculty of Sciences Semlalia, University of Cadi Ayyad, Marrakech, Morocco

  • Nuclear Physics and Techniques Laboratory, Faculty of Sciences Semlalia, University of Cadi Ayyad, Marrakech, Morocco

  • Nuclear Physics and Techniques Laboratory, Faculty of Sciences Semlalia, University of Cadi Ayyad, Marrakech, Morocco

  • Nuclear Physics and Techniques Laboratory, Faculty of Sciences Semlalia, University of Cadi Ayyad, Marrakech, Morocco; Nuclear Medicine Service, Mohamed VI University Hospital Centre, Faculty of Medicine and Pharmacy, University of Cadi Ayyad, Marrakech, Morocco

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