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Case Reports on Juvenile Xanthogranuloma and Brief Review of Literature

Received: 18 February 2017    Accepted: 18 March 2017    Published: 24 October 2017
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Abstract

Juvenile xanthogranuloma is an unusual, self-limiting dermatological disorder occurring especially in infants, late childhood and rarely in adults. It belongs to the broad group of non-Langerhans cell histiocytosis. It usually appears as solitary or multiple papules, macules or nodules several millimeters in diameter with the head and neck being the most common site of involvement and vulva being the rare site. We report two cases of juvenile xanthogranuloma in an 18 months old female and 18 months old male. The female presented with three yellow papules measuring 2-3 mm in diameter around vulva region since 4 months. Similarly, the male presented with multiple tan-orange color macules on head and forehead measuring 3-4mm in diameter since 6 months. In both the cases, a biopsy without total excision was performed. The clinical and histopathological evaluation confirmed the diagnosis of juvenile xanthogranuloma. In childhood, juvenile xanthogranuloma is necessary to differentiate from another probable differential diagnosis by biopsy.

Published in Science Journal of Clinical Medicine (Volume 6, Issue 5)
DOI 10.11648/j.sjcm.20170605.14
Page(s) 82-85
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Xanthogranuloma, Juvenile, Children

References
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  • APA Style

    Sushmita Pradhan, Shuang Chen, Lin Xiong. (2017). Case Reports on Juvenile Xanthogranuloma and Brief Review of Literature. Science Journal of Clinical Medicine, 6(5), 82-85. https://doi.org/10.11648/j.sjcm.20170605.14

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    ACS Style

    Sushmita Pradhan; Shuang Chen; Lin Xiong. Case Reports on Juvenile Xanthogranuloma and Brief Review of Literature. Sci. J. Clin. Med. 2017, 6(5), 82-85. doi: 10.11648/j.sjcm.20170605.14

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    AMA Style

    Sushmita Pradhan, Shuang Chen, Lin Xiong. Case Reports on Juvenile Xanthogranuloma and Brief Review of Literature. Sci J Clin Med. 2017;6(5):82-85. doi: 10.11648/j.sjcm.20170605.14

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  • @article{10.11648/j.sjcm.20170605.14,
      author = {Sushmita Pradhan and Shuang Chen and Lin Xiong},
      title = {Case Reports on Juvenile Xanthogranuloma and Brief Review of Literature},
      journal = {Science Journal of Clinical Medicine},
      volume = {6},
      number = {5},
      pages = {82-85},
      doi = {10.11648/j.sjcm.20170605.14},
      url = {https://doi.org/10.11648/j.sjcm.20170605.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20170605.14},
      abstract = {Juvenile xanthogranuloma is an unusual, self-limiting dermatological disorder occurring especially in infants, late childhood and rarely in adults. It belongs to the broad group of non-Langerhans cell histiocytosis. It usually appears as solitary or multiple papules, macules or nodules several millimeters in diameter with the head and neck being the most common site of involvement and vulva being the rare site. We report two cases of juvenile xanthogranuloma in an 18 months old female and 18 months old male. The female presented with three yellow papules measuring 2-3 mm in diameter around vulva region since 4 months. Similarly, the male presented with multiple tan-orange color macules on head and forehead measuring 3-4mm in diameter since 6 months. In both the cases, a biopsy without total excision was performed. The clinical and histopathological evaluation confirmed the diagnosis of juvenile xanthogranuloma. In childhood, juvenile xanthogranuloma is necessary to differentiate from another probable differential diagnosis by biopsy.},
     year = {2017}
    }
    

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    AU  - Sushmita Pradhan
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    T2  - Science Journal of Clinical Medicine
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    AB  - Juvenile xanthogranuloma is an unusual, self-limiting dermatological disorder occurring especially in infants, late childhood and rarely in adults. It belongs to the broad group of non-Langerhans cell histiocytosis. It usually appears as solitary or multiple papules, macules or nodules several millimeters in diameter with the head and neck being the most common site of involvement and vulva being the rare site. We report two cases of juvenile xanthogranuloma in an 18 months old female and 18 months old male. The female presented with three yellow papules measuring 2-3 mm in diameter around vulva region since 4 months. Similarly, the male presented with multiple tan-orange color macules on head and forehead measuring 3-4mm in diameter since 6 months. In both the cases, a biopsy without total excision was performed. The clinical and histopathological evaluation confirmed the diagnosis of juvenile xanthogranuloma. In childhood, juvenile xanthogranuloma is necessary to differentiate from another probable differential diagnosis by biopsy.
    VL  - 6
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Author Information
  • Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China

  • Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

  • Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China

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