Science Journal of Clinical Medicine

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Comparative Effect of Natural Commodities and Commercial Medicines Against Oral Thrush Causing Fungal Organism of Candida Albicans

Received: 17 May 2013    Accepted:     Published: 10 June 2013
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Abstract

The aim of the study was to explore the comparative analysis antifungal efficiency of six natural commodities and four commercial medicines against the oral thrush causing organism of Candida albicans. From the present result along with the six natural commodities, Mayaca showed maximum inhibitory activity against C. albicans followed by garlic, gooseberry, wine, coconut oil and pomegranate. While, the significant antifungal activity noted in Mayaca ehtanolic extract against C. albicans at 50 and 100µl concentration (P<0.05), and other natural substances such as garlic and gooseberry antifungal activity also expressed significantly. In the GC-MS analysis ten bioactive compounds were identified in the ehtanolic extract. Besides the identified bioactive peak phytochemical compounds named as 3,4-Dimethyl-2-3-methyl with its Ret. time 19.050 followed by second and third peak compounds are Diethylpthalate and Bis-3,4 methylene Dioxy accompanied with them responsible RT was 21.004 and 28.666 respectively. The overall results clearly denoted ethanol extract of Mayaca act as significant antifungal C. albicans agent mainly it was possessed specific antimicrobial secondary metabolic compounds present than other five natural commodities and four commercial products. Hence, the present study focused that the Mayaca extract act as a potential antifungal agent for oral thrush causing fungi of C. albicans.

DOI 10.11648/j.sjcm.20130203.13
Published in Science Journal of Clinical Medicine (Volume 2, Issue 3, May 2013)
Page(s) 75-80
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Candida Albicans, Natural Commodities, Mayaca, GC-MS

References
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Author Information
  • Department of Microbiology, Malanakara Catholic College, Mariagiri, Kaliakkavilai

  • Department of Microbiology, Malanakara Catholic College, Mariagiri, Kaliakkavilai

  • International Centre for Bioresources Management, Malanakara Catholic College, Mariagiri, Kaliakkavilai

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  • APA Style

    Reena, T, Rohitha Prem, Deepthi, M. S, et al. (2013). Comparative Effect of Natural Commodities and Commercial Medicines Against Oral Thrush Causing Fungal Organism of Candida Albicans. Science Journal of Clinical Medicine, 2(3), 75-80. https://doi.org/10.11648/j.sjcm.20130203.13

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    ACS Style

    Reena; T; Rohitha Prem; Deepthi; M. S, et al. Comparative Effect of Natural Commodities and Commercial Medicines Against Oral Thrush Causing Fungal Organism of Candida Albicans. Sci. J. Clin. Med. 2013, 2(3), 75-80. doi: 10.11648/j.sjcm.20130203.13

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    AMA Style

    Reena, T, Rohitha Prem, Deepthi, M. S, et al. Comparative Effect of Natural Commodities and Commercial Medicines Against Oral Thrush Causing Fungal Organism of Candida Albicans. Sci J Clin Med. 2013;2(3):75-80. doi: 10.11648/j.sjcm.20130203.13

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  • @article{10.11648/j.sjcm.20130203.13,
      author = {Reena and T and Rohitha Prem and Deepthi and M. S and R. Beni Ramachanran and S. Sujatha},
      title = {Comparative Effect of Natural Commodities and Commercial Medicines Against Oral Thrush Causing Fungal Organism of Candida Albicans},
      journal = {Science Journal of Clinical Medicine},
      volume = {2},
      number = {3},
      pages = {75-80},
      doi = {10.11648/j.sjcm.20130203.13},
      url = {https://doi.org/10.11648/j.sjcm.20130203.13},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.sjcm.20130203.13},
      abstract = {The aim of the study was to explore the comparative analysis antifungal efficiency of six natural commodities and four commercial medicines against the oral thrush causing organism of Candida albicans. From the present result along with the six natural commodities, Mayaca showed maximum inhibitory activity against C. albicans followed by garlic, gooseberry, wine, coconut oil and pomegranate. While, the significant antifungal activity noted in Mayaca ehtanolic extract against C. albicans at 50 and 100µl concentration (P<0.05), and other natural substances such as garlic and gooseberry antifungal activity also expressed significantly. In the GC-MS analysis ten bioactive compounds were identified in the ehtanolic extract. Besides the identified bioactive peak phytochemical compounds named as 3,4-Dimethyl-2-3-methyl with its Ret. time 19.050 followed by second and third peak compounds are Diethylpthalate and Bis-3,4 methylene Dioxy accompanied with them responsible RT was 21.004 and 28.666 respectively. The overall results clearly denoted ethanol extract of Mayaca act as significant antifungal C. albicans agent mainly it was possessed specific antimicrobial secondary metabolic compounds present than other five natural commodities and four commercial products. Hence, the present study focused that the Mayaca extract act as a potential antifungal agent for oral thrush causing fungi of C. albicans.},
     year = {2013}
    }
    

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  • TY  - JOUR
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    AU  - Reena
    AU  - T
    AU  - Rohitha Prem
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    JF  - Science Journal of Clinical Medicine
    JO  - Science Journal of Clinical Medicine
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    AB  - The aim of the study was to explore the comparative analysis antifungal efficiency of six natural commodities and four commercial medicines against the oral thrush causing organism of Candida albicans. From the present result along with the six natural commodities, Mayaca showed maximum inhibitory activity against C. albicans followed by garlic, gooseberry, wine, coconut oil and pomegranate. While, the significant antifungal activity noted in Mayaca ehtanolic extract against C. albicans at 50 and 100µl concentration (P<0.05), and other natural substances such as garlic and gooseberry antifungal activity also expressed significantly. In the GC-MS analysis ten bioactive compounds were identified in the ehtanolic extract. Besides the identified bioactive peak phytochemical compounds named as 3,4-Dimethyl-2-3-methyl with its Ret. time 19.050 followed by second and third peak compounds are Diethylpthalate and Bis-3,4 methylene Dioxy accompanied with them responsible RT was 21.004 and 28.666 respectively. The overall results clearly denoted ethanol extract of Mayaca act as significant antifungal C. albicans agent mainly it was possessed specific antimicrobial secondary metabolic compounds present than other five natural commodities and four commercial products. Hence, the present study focused that the Mayaca extract act as a potential antifungal agent for oral thrush causing fungi of C. albicans.
    VL  - 2
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