Objective: To describe the clinical, epidemiological and biological profile of polycythemia vera. Patients and methods: This is a descriptive study done from May to October 2014 witch included 13 patient who had been treated since 2007 at Campus Teaching Hospital of Lomé for polycythemia vera. The research of JAK2 V617Fmutation by PCR was been done inmolecular biologylaboratory of the Henri Mondor Hospital at Creteil in France. Results: The annual prevalence of polycythemia vera is about 2.16 new cases. The average age of patients was 46, 7 years with ranges from 31 to 65 years. There were 9 men and 4 women. The most frequent factor of finding was the fortuitous ones (23%). Most clinical signs represented were headache (69.2%), skin érythroses (53.8%) and paresthesia (30.8%). The average value of hemoglobin, hematocrit, the number of white blood cells and platelets in our patients with polycythemia who had positive JAK2V617F was respectively: 198g/L ± 44; 62.7 ± 4.4%; 9.8 G/L ± 4.3, 630.4G /l ± 367.4. Those Who didn’t had JAK2mutation, had respectively: 179g/L ± 13.3; 59,0% ± 13.3; 7.5G/L ± 4.2 GB and 441.0G /L ± 564.7. Conclusion: The JAK2V617F mutation had an interestin polycythemia vera value in diagnosis and can be systematic even in Sub-Saharan African.
| Published in | Cancer Research Journal (Volume 4, Issue 1) |
| DOI | 10.11648/j.crj.20160401.13 |
| Page(s) | 24-27 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Polycythemia Vera, JAK 2 Changes, Lome (Togo)
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APA Style
Padaro Essohana, Kueviakoe Irenee Messanh Delagnon, Layibo Yao, Kolou Malewe, Agbetiafa Kossi, et al. (2016). Profile of Polycythemia Vera in Campus Teaching Hospital of Lome - Togo. Cancer Research Journal, 4(1), 24-27. https://doi.org/10.11648/j.crj.20160401.13
ACS Style
Padaro Essohana; Kueviakoe Irenee Messanh Delagnon; Layibo Yao; Kolou Malewe; Agbetiafa Kossi, et al. Profile of Polycythemia Vera in Campus Teaching Hospital of Lome - Togo. Cancer Res. J. 2016, 4(1), 24-27. doi: 10.11648/j.crj.20160401.13
AMA Style
Padaro Essohana, Kueviakoe Irenee Messanh Delagnon, Layibo Yao, Kolou Malewe, Agbetiafa Kossi, et al. Profile of Polycythemia Vera in Campus Teaching Hospital of Lome - Togo. Cancer Res J. 2016;4(1):24-27. doi: 10.11648/j.crj.20160401.13
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Download@article{10.11648/j.crj.20160401.13,
author = {Padaro Essohana and Kueviakoe Irenee Messanh Delagnon and Layibo Yao and Kolou Malewe and Agbetiafa Kossi and Stephane Giraudier and Segbena Akuete Yvon},
title = {Profile of Polycythemia Vera in Campus Teaching Hospital of Lome - Togo},
journal = {Cancer Research Journal},
volume = {4},
number = {1},
pages = {24-27},
doi = {10.11648/j.crj.20160401.13},
url = {https://doi.org/10.11648/j.crj.20160401.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20160401.13},
abstract = {Objective: To describe the clinical, epidemiological and biological profile of polycythemia vera. Patients and methods: This is a descriptive study done from May to October 2014 witch included 13 patient who had been treated since 2007 at Campus Teaching Hospital of Lomé for polycythemia vera. The research of JAK2 V617Fmutation by PCR was been done inmolecular biologylaboratory of the Henri Mondor Hospital at Creteil in France. Results: The annual prevalence of polycythemia vera is about 2.16 new cases. The average age of patients was 46, 7 years with ranges from 31 to 65 years. There were 9 men and 4 women. The most frequent factor of finding was the fortuitous ones (23%). Most clinical signs represented were headache (69.2%), skin érythroses (53.8%) and paresthesia (30.8%). The average value of hemoglobin, hematocrit, the number of white blood cells and platelets in our patients with polycythemia who had positive JAK2V617F was respectively: 198g/L ± 44; 62.7 ± 4.4%; 9.8 G/L ± 4.3, 630.4G /l ± 367.4. Those Who didn’t had JAK2mutation, had respectively: 179g/L ± 13.3; 59,0% ± 13.3; 7.5G/L ± 4.2 GB and 441.0G /L ± 564.7. Conclusion: The JAK2V617F mutation had an interestin polycythemia vera value in diagnosis and can be systematic even in Sub-Saharan African.},
year = {2016}
}
TY - JOUR T1 - Profile of Polycythemia Vera in Campus Teaching Hospital of Lome - Togo AU - Padaro Essohana AU - Kueviakoe Irenee Messanh Delagnon AU - Layibo Yao AU - Kolou Malewe AU - Agbetiafa Kossi AU - Stephane Giraudier AU - Segbena Akuete Yvon Y1 - 2016/02/29 PY - 2016 N1 - https://doi.org/10.11648/j.crj.20160401.13 DO - 10.11648/j.crj.20160401.13 T2 - Cancer Research Journal JF - Cancer Research Journal JO - Cancer Research Journal SP - 24 EP - 27 PB - Science Publishing Group SN - 2330-8214 UR - https://doi.org/10.11648/j.crj.20160401.13 AB - Objective: To describe the clinical, epidemiological and biological profile of polycythemia vera. Patients and methods: This is a descriptive study done from May to October 2014 witch included 13 patient who had been treated since 2007 at Campus Teaching Hospital of Lomé for polycythemia vera. The research of JAK2 V617Fmutation by PCR was been done inmolecular biologylaboratory of the Henri Mondor Hospital at Creteil in France. Results: The annual prevalence of polycythemia vera is about 2.16 new cases. The average age of patients was 46, 7 years with ranges from 31 to 65 years. There were 9 men and 4 women. The most frequent factor of finding was the fortuitous ones (23%). Most clinical signs represented were headache (69.2%), skin érythroses (53.8%) and paresthesia (30.8%). The average value of hemoglobin, hematocrit, the number of white blood cells and platelets in our patients with polycythemia who had positive JAK2V617F was respectively: 198g/L ± 44; 62.7 ± 4.4%; 9.8 G/L ± 4.3, 630.4G /l ± 367.4. Those Who didn’t had JAK2mutation, had respectively: 179g/L ± 13.3; 59,0% ± 13.3; 7.5G/L ± 4.2 GB and 441.0G /L ± 564.7. Conclusion: The JAK2V617F mutation had an interestin polycythemia vera value in diagnosis and can be systematic even in Sub-Saharan African. VL - 4 IS - 1 ER -
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