Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography

Wencai Yang; Zhaohui Xian; Feifeng Qiu; Nengwei Wang; Sihua Liang; Lin Qiu

doi:doi:10.11648/j.ijmi.20200804.11

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Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography

Wencai Yang, Zhaohui Xian, Feifeng Qiu, Nengwei Wang, Sihua Liang, Lin Qiu

Published in International Journal of Medical Imaging (Volume 8, Issue 4)

Received: 24 August 2020 Accepted: 6 October 2020 Published: 16 October 2020

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Abstract

Background: 320-detector row dynamic volume computed tomography (CT) scanner was widely applied in coronary CT angiography (CCTA)，which made it possible to reduce the volume of contrast material (CM) used. Some studies have reported the feasibility of reducing the CM in 320-detector row CCTA using a weight-adapted injection protocol. However, it hasn't been studied to investigate what was the significance of increasing the injection rate with a lower volume of CM. Objective: To investigate the feasibility of reducing the body weight-adapted volume of CM by increasing the injection rate in 320-detector row CCTA. Methods: A total of 116 patients who underwent 320-detector row CCTA were divided into three groups. Group A received 0.7 ml/kg of CM (350 mg I/ml) at an injection rate of 5.0 ml/s (n = 40); group B received 0.6 ml/kg of CM at 5.5 ml/s (n = 39); group C received 0.5 ml/kg of CM at 6.0 ml/s (n = 37). A 30-ml 0.9% saline chaser was administered after the CM. Enhancement values of the cardiovascular territories and coronary arteries were measured and compared. Image quality was also evaluated and compared among the three groups. Result: Enhancement values of the proximal coronary arterial segments for group C were significantly lower than those for groups A and B (all, P < 0.05), whereas there were no significant differences between groups A and B (all, P > 0.05). Similar statistical results were found in the proportion of proximal coronary arterial segments with enhancement values ≥ 300 HU, image quality ratings and the proportion of the main of coronary arterial segments with image quality scores ≥ 3 on both per-vessel and per-patient analyses. Conclusion: At least 0.6 ml/kg with 350 mg I/ml of CM at 5.5 ml/s injection rate was required to achieve sufficient and credible evaluation of the coronary artery in 320-detector row CCTA.

Published in	International Journal of Medical Imaging (Volume 8, Issue 4)
DOI	10.11648/j.ijmi.20200804.11
Page(s)	65-71
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Coronary CT Angiography, 320-detector Row CT, Contrast Material, Injection Rate, Image Quality

References

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[2]	Fuchs A, Kühl JT, Chen MY, et al. Subtraction CT angiography improves evaluation of significant coronary artery disease in patients with severe calcifications or stents-the C-Sub 320 multicenter trial.[J]. European Radiology. 2018, 28 (10): 4077-4085.
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[7]	Bao L. Optimization of contrast dose of the 320-slice spiral CT coronary angiography [J]. Journal of Imaging Research and Medical Applications, 2018, 2 (13): 37-38.
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[13]	Kawaguchi N, Kurata A, Kido T,, et al. Optimization of coronary attenuation in coronary computed tomography angiography using diluted contrast material [J]. Circulation journal, 2014, 78 (3): 662-670.
[14]	Bae, YK. Intravenous contrast medium administration and scan timing at CT: considerations and approaches [J]. Radiology, 2010, 256 (1): 32-61.
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APA Style

Wencai Yang, Zhaohui Xian, Feifeng Qiu, Nengwei Wang, Sihua Liang, et al. (2020). Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography. International Journal of Medical Imaging, 8(4), 65-71. https://doi.org/10.11648/j.ijmi.20200804.11

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ACS Style

Wencai Yang; Zhaohui Xian; Feifeng Qiu; Nengwei Wang; Sihua Liang, et al. Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography. Int. J. Med. Imaging 2020, 8(4), 65-71. doi: 10.11648/j.ijmi.20200804.11

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AMA Style

Wencai Yang, Zhaohui Xian, Feifeng Qiu, Nengwei Wang, Sihua Liang, et al. Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography. Int J Med Imaging. 2020;8(4):65-71. doi: 10.11648/j.ijmi.20200804.11

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@article{10.11648/j.ijmi.20200804.11,
  author = {Wencai Yang and Zhaohui Xian and Feifeng Qiu and Nengwei Wang and Sihua Liang and Lin Qiu},
  title = {Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography},
  journal = {International Journal of Medical Imaging},
  volume = {8},
  number = {4},
  pages = {65-71},
  doi = {10.11648/j.ijmi.20200804.11},
  url = {https://doi.org/10.11648/j.ijmi.20200804.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20200804.11},
  abstract = {Background: 320-detector row dynamic volume computed tomography (CT) scanner was widely applied in coronary CT angiography (CCTA)，which made it possible to reduce the volume of contrast material (CM) used. Some studies have reported the feasibility of reducing the CM in 320-detector row CCTA using a weight-adapted injection protocol. However, it hasn't been studied to investigate what was the significance of increasing the injection rate with a lower volume of CM. Objective: To investigate the feasibility of reducing the body weight-adapted volume of CM by increasing the injection rate in 320-detector row CCTA. Methods: A total of 116 patients who underwent 320-detector row CCTA were divided into three groups. Group A received 0.7 ml/kg of CM (350 mg I/ml) at an injection rate of 5.0 ml/s (n = 40); group B received 0.6 ml/kg of CM at 5.5 ml/s (n = 39); group C received 0.5 ml/kg of CM at 6.0 ml/s (n = 37). A 30-ml 0.9% saline chaser was administered after the CM. Enhancement values of the cardiovascular territories and coronary arteries were measured and compared. Image quality was also evaluated and compared among the three groups. Result: Enhancement values of the proximal coronary arterial segments for group C were significantly lower than those for groups A and B (all, P P > 0.05). Similar statistical results were found in the proportion of proximal coronary arterial segments with enhancement values ≥ 300 HU, image quality ratings and the proportion of the main of coronary arterial segments with image quality scores ≥ 3 on both per-vessel and per-patient analyses. Conclusion: At least 0.6 ml/kg with 350 mg I/ml of CM at 5.5 ml/s injection rate was required to achieve sufficient and credible evaluation of the coronary artery in 320-detector row CCTA.},
 year = {2020}
}

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TY  - JOUR
T1  - Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography
AU  - Wencai Yang
AU  - Zhaohui Xian
AU  - Feifeng Qiu
AU  - Nengwei Wang
AU  - Sihua Liang
AU  - Lin Qiu
Y1  - 2020/10/16
PY  - 2020
N1  - https://doi.org/10.11648/j.ijmi.20200804.11
DO  - 10.11648/j.ijmi.20200804.11
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 65
EP  - 71
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20200804.11
AB  - Background: 320-detector row dynamic volume computed tomography (CT) scanner was widely applied in coronary CT angiography (CCTA)，which made it possible to reduce the volume of contrast material (CM) used. Some studies have reported the feasibility of reducing the CM in 320-detector row CCTA using a weight-adapted injection protocol. However, it hasn't been studied to investigate what was the significance of increasing the injection rate with a lower volume of CM. Objective: To investigate the feasibility of reducing the body weight-adapted volume of CM by increasing the injection rate in 320-detector row CCTA. Methods: A total of 116 patients who underwent 320-detector row CCTA were divided into three groups. Group A received 0.7 ml/kg of CM (350 mg I/ml) at an injection rate of 5.0 ml/s (n = 40); group B received 0.6 ml/kg of CM at 5.5 ml/s (n = 39); group C received 0.5 ml/kg of CM at 6.0 ml/s (n = 37). A 30-ml 0.9% saline chaser was administered after the CM. Enhancement values of the cardiovascular territories and coronary arteries were measured and compared. Image quality was also evaluated and compared among the three groups. Result: Enhancement values of the proximal coronary arterial segments for group C were significantly lower than those for groups A and B (all, P P > 0.05). Similar statistical results were found in the proportion of proximal coronary arterial segments with enhancement values ≥ 300 HU, image quality ratings and the proportion of the main of coronary arterial segments with image quality scores ≥ 3 on both per-vessel and per-patient analyses. Conclusion: At least 0.6 ml/kg with 350 mg I/ml of CM at 5.5 ml/s injection rate was required to achieve sufficient and credible evaluation of the coronary artery in 320-detector row CCTA.
VL  - 8
IS  - 4
ER  -

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Author Information

Wencai Yang

nterventional Operating Room, The First Affiliated Hospital of Jinan University, Guangzhou, China
Zhaohui Xian

nterventional Operating Room, The First Affiliated Hospital of Jinan University, Guangzhou, China
Feifeng Qiu

nterventional Operating Room, The First Affiliated Hospital of Jinan University, Guangzhou, China
Nengwei Wang

Medical Imaging Department, The First Affiliated Hospital of Jinan University, Guangzhou, China
Sihua Liang

Medical Imaging Department, The First Affiliated Hospital of Jinan University, Guangzhou, China
Lin Qiu

Medical Imaging Department, The First Affiliated Hospital of Jinan University, Guangzhou, China

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Plain Text BibTeX RIS

APA Style

Wencai Yang, Zhaohui Xian, Feifeng Qiu, Nengwei Wang, Sihua Liang, et al. (2020). Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography. International Journal of Medical Imaging, 8(4), 65-71. https://doi.org/10.11648/j.ijmi.20200804.11

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ACS Style

Wencai Yang; Zhaohui Xian; Feifeng Qiu; Nengwei Wang; Sihua Liang, et al. Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography. Int. J. Med. Imaging 2020, 8(4), 65-71. doi: 10.11648/j.ijmi.20200804.11

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AMA Style

Wencai Yang, Zhaohui Xian, Feifeng Qiu, Nengwei Wang, Sihua Liang, et al. Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography. Int J Med Imaging. 2020;8(4):65-71. doi: 10.11648/j.ijmi.20200804.11

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@article{10.11648/j.ijmi.20200804.11,
  author = {Wencai Yang and Zhaohui Xian and Feifeng Qiu and Nengwei Wang and Sihua Liang and Lin Qiu},
  title = {Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography},
  journal = {International Journal of Medical Imaging},
  volume = {8},
  number = {4},
  pages = {65-71},
  doi = {10.11648/j.ijmi.20200804.11},
  url = {https://doi.org/10.11648/j.ijmi.20200804.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20200804.11},
  abstract = {Background: 320-detector row dynamic volume computed tomography (CT) scanner was widely applied in coronary CT angiography (CCTA)，which made it possible to reduce the volume of contrast material (CM) used. Some studies have reported the feasibility of reducing the CM in 320-detector row CCTA using a weight-adapted injection protocol. However, it hasn't been studied to investigate what was the significance of increasing the injection rate with a lower volume of CM. Objective: To investigate the feasibility of reducing the body weight-adapted volume of CM by increasing the injection rate in 320-detector row CCTA. Methods: A total of 116 patients who underwent 320-detector row CCTA were divided into three groups. Group A received 0.7 ml/kg of CM (350 mg I/ml) at an injection rate of 5.0 ml/s (n = 40); group B received 0.6 ml/kg of CM at 5.5 ml/s (n = 39); group C received 0.5 ml/kg of CM at 6.0 ml/s (n = 37). A 30-ml 0.9% saline chaser was administered after the CM. Enhancement values of the cardiovascular territories and coronary arteries were measured and compared. Image quality was also evaluated and compared among the three groups. Result: Enhancement values of the proximal coronary arterial segments for group C were significantly lower than those for groups A and B (all, P P > 0.05). Similar statistical results were found in the proportion of proximal coronary arterial segments with enhancement values ≥ 300 HU, image quality ratings and the proportion of the main of coronary arterial segments with image quality scores ≥ 3 on both per-vessel and per-patient analyses. Conclusion: At least 0.6 ml/kg with 350 mg I/ml of CM at 5.5 ml/s injection rate was required to achieve sufficient and credible evaluation of the coronary artery in 320-detector row CCTA.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Reduction of the Body Weight-adapted Volume of Contrast Material by Increasing the Injection Rate in 320-detector Row Coronary CT Angiography
AU  - Wencai Yang
AU  - Zhaohui Xian
AU  - Feifeng Qiu
AU  - Nengwei Wang
AU  - Sihua Liang
AU  - Lin Qiu
Y1  - 2020/10/16
PY  - 2020
N1  - https://doi.org/10.11648/j.ijmi.20200804.11
DO  - 10.11648/j.ijmi.20200804.11
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 65
EP  - 71
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20200804.11
AB  - Background: 320-detector row dynamic volume computed tomography (CT) scanner was widely applied in coronary CT angiography (CCTA)，which made it possible to reduce the volume of contrast material (CM) used. Some studies have reported the feasibility of reducing the CM in 320-detector row CCTA using a weight-adapted injection protocol. However, it hasn't been studied to investigate what was the significance of increasing the injection rate with a lower volume of CM. Objective: To investigate the feasibility of reducing the body weight-adapted volume of CM by increasing the injection rate in 320-detector row CCTA. Methods: A total of 116 patients who underwent 320-detector row CCTA were divided into three groups. Group A received 0.7 ml/kg of CM (350 mg I/ml) at an injection rate of 5.0 ml/s (n = 40); group B received 0.6 ml/kg of CM at 5.5 ml/s (n = 39); group C received 0.5 ml/kg of CM at 6.0 ml/s (n = 37). A 30-ml 0.9% saline chaser was administered after the CM. Enhancement values of the cardiovascular territories and coronary arteries were measured and compared. Image quality was also evaluated and compared among the three groups. Result: Enhancement values of the proximal coronary arterial segments for group C were significantly lower than those for groups A and B (all, P P > 0.05). Similar statistical results were found in the proportion of proximal coronary arterial segments with enhancement values ≥ 300 HU, image quality ratings and the proportion of the main of coronary arterial segments with image quality scores ≥ 3 on both per-vessel and per-patient analyses. Conclusion: At least 0.6 ml/kg with 350 mg I/ml of CM at 5.5 ml/s injection rate was required to achieve sufficient and credible evaluation of the coronary artery in 320-detector row CCTA.
VL  - 8
IS  - 4
ER  -

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