Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer
International Journal of Medical Imaging
Volume 3, Issue 6, November 2015, Pages: 137-142
Received: Oct. 31, 2015; Accepted: Nov. 10, 2015; Published: Nov. 26, 2015
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Ashraf Anas Zytoon, Radiology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Eman Abdel Razek Tawfek, Nuclear Medicine & Clinical Oncology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Adel Mohamed Elwakil, Radiology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Gilan Ibrahim Aladle, Radiology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt
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Prostate cancer (PCa) represents the most common non-cutaneous malignancy for men, where an estimated 241,740 new cases will be diagnosed in 2013 in the United States [1]. Whereas most of those new diagnoses will be clinically localized, up to 17% of patients may experience metastatic disease, in which the risk of cancer- specific mortality is increased [2]. In this context, it is well established that, beyond regional lymph nodes, the skeleton represents the most common metastatic site [3].The study aims to evaluate the pattern of distribution of bone metastases in prostate cancer patients by 99mTc- methylene diphosphonate (99mTc-MDP) bone scintigraphy. It was formed in 150 patients with pathologically proven prostate cancer and presented for bone scans with 99mTc-methylene diphosphonate (99mTc-MDP) for detection and evaluation of bone metastases. It was noted that patients with bone metastases had significantly higher frequency of bone pain when compared with patients without and noted that spine was the most commonly affected site (60.0 %) followed by ribs (52.0 %) and femur (30.0 %). Spread of bony metastases among the bony skeleton has distribution manner not only to the right or to the left. Metastatic bony lesions of prostate cancer are located mainly in spine (58.0%) followed by ribs (52.0 %) and femur (30.0 %). Patients with extensive bone metastasis had significantly higher frequency of skull, spine, scapula, humerous, sternum, ribs, iliac bone, ischium, and femur metastases
Prostate Cancer, Bone Scan, Bone Metastases, MDP
To cite this article
Ashraf Anas Zytoon, Eman Abdel Razek Tawfek, Adel Mohamed Elwakil, Gilan Ibrahim Aladle, Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer, International Journal of Medical Imaging. Vol. 3, No. 6, 2015, pp. 137-142. doi: 10.11648/j.ijmi.20150306.15
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