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Mechanical Mitral Valve Modeling: Advancing the Field through Emerging Science

Received: 24 February 2014    Accepted:     Published: 30 March 2014
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Abstract

Background: Successful mitral valve repair and replacement are dependent upon a full understanding of normal and abnormal mitral valve anatomy and function. The functional components of the mitral valve include: the left atrial wall, the annulus, the leaflets, the chordae tendineae, the papillary muscles, segments of the left ventricular myocardium. Abnormal anatomy or function of any one of these components can result in valvular dysfunction. We sought to assess the outcome of olden challenges of the mechanical behaviors of the mitral valve. Method: Much of our knowledge of abnormal mitral valve function is based on surgical and post-mortem studies while these studies are quantitative in some cases , they are limited by evaluation of valve anatomy in a fixed and nonfunctioning state. A more sophisticated analysis method is necessary to gain a full considerate of mitral valve function. Several groups attempted to model mitral valve anatomy and function by mathematical/physical equations. Result: Preliminary results concerning a different aspect of mitral valve leafletsbiomechanics, such as leaflets dynamics, displacements, thickness, stress and strain on leaflets. Conclusion: These data potentially allow the implementation of an image-based approach for patient-specific modeling of mitral valve leaflets. This approach could constitute the basis for accurate evaluation of mitral valve pathologic conditions and for the planning of surgical approaches.

Published in International Journal of Medical Imaging (Volume 2, Issue 2)
DOI 10.11648/j.ijmi.20140202.14
Page(s) 24-28
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Mitral Valve, Mathematical Modeling, Finite Element Method, Stress-Strain of Leaflets,the Geometry of Mitral Valve, Fluid–Structure Interactions

References
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[5] Pierrakos, O., Vlachos, P.P. The effect of vortex formation on left ventricular fillingand mitral valve efficiency. J BiomechEng2006; 128, 527–539.
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Cite This Article
  • APA Style

    Mersedeh Karvandi, Saeed Ranjbar, Seyed Ahmad Hassantash. (2014). Mechanical Mitral Valve Modeling: Advancing the Field through Emerging Science. International Journal of Medical Imaging, 2(2), 24-28. https://doi.org/10.11648/j.ijmi.20140202.14

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    ACS Style

    Mersedeh Karvandi; Saeed Ranjbar; Seyed Ahmad Hassantash. Mechanical Mitral Valve Modeling: Advancing the Field through Emerging Science. Int. J. Med. Imaging 2014, 2(2), 24-28. doi: 10.11648/j.ijmi.20140202.14

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    AMA Style

    Mersedeh Karvandi, Saeed Ranjbar, Seyed Ahmad Hassantash. Mechanical Mitral Valve Modeling: Advancing the Field through Emerging Science. Int J Med Imaging. 2014;2(2):24-28. doi: 10.11648/j.ijmi.20140202.14

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  • @article{10.11648/j.ijmi.20140202.14,
      author = {Mersedeh Karvandi and Saeed Ranjbar and Seyed Ahmad Hassantash},
      title = {Mechanical Mitral Valve Modeling: Advancing the Field through Emerging Science},
      journal = {International Journal of Medical Imaging},
      volume = {2},
      number = {2},
      pages = {24-28},
      doi = {10.11648/j.ijmi.20140202.14},
      url = {https://doi.org/10.11648/j.ijmi.20140202.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20140202.14},
      abstract = {Background: Successful mitral valve repair and replacement are dependent upon a full understanding of normal and abnormal mitral valve anatomy and function. The functional components of the mitral valve include: the left atrial wall, the annulus, the leaflets, the chordae tendineae, the papillary muscles, segments of the left ventricular myocardium. Abnormal anatomy or function of any one of these components can result in valvular dysfunction. We sought to assess the outcome of olden challenges of the mechanical behaviors of the mitral valve. Method: Much of our knowledge of abnormal mitral valve function is based on surgical and post-mortem studies while these studies are quantitative in some cases , they are limited by evaluation of valve anatomy in a fixed and nonfunctioning state. A more sophisticated analysis method is necessary to gain a full considerate of mitral valve function. Several groups attempted to model mitral valve anatomy and function by mathematical/physical equations. Result: Preliminary results concerning a different aspect of mitral valve leafletsbiomechanics, such as leaflets dynamics, displacements, thickness, stress and strain on leaflets. Conclusion: These data potentially allow the implementation of an image-based approach for patient-specific modeling of mitral valve leaflets. This approach could constitute the basis for accurate evaluation of mitral valve pathologic conditions and for the planning of surgical approaches.},
     year = {2014}
    }
    

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  • TY  - JOUR
    T1  - Mechanical Mitral Valve Modeling: Advancing the Field through Emerging Science
    AU  - Mersedeh Karvandi
    AU  - Saeed Ranjbar
    AU  - Seyed Ahmad Hassantash
    Y1  - 2014/03/30
    PY  - 2014
    N1  - https://doi.org/10.11648/j.ijmi.20140202.14
    DO  - 10.11648/j.ijmi.20140202.14
    T2  - International Journal of Medical Imaging
    JF  - International Journal of Medical Imaging
    JO  - International Journal of Medical Imaging
    SP  - 24
    EP  - 28
    PB  - Science Publishing Group
    SN  - 2330-832X
    UR  - https://doi.org/10.11648/j.ijmi.20140202.14
    AB  - Background: Successful mitral valve repair and replacement are dependent upon a full understanding of normal and abnormal mitral valve anatomy and function. The functional components of the mitral valve include: the left atrial wall, the annulus, the leaflets, the chordae tendineae, the papillary muscles, segments of the left ventricular myocardium. Abnormal anatomy or function of any one of these components can result in valvular dysfunction. We sought to assess the outcome of olden challenges of the mechanical behaviors of the mitral valve. Method: Much of our knowledge of abnormal mitral valve function is based on surgical and post-mortem studies while these studies are quantitative in some cases , they are limited by evaluation of valve anatomy in a fixed and nonfunctioning state. A more sophisticated analysis method is necessary to gain a full considerate of mitral valve function. Several groups attempted to model mitral valve anatomy and function by mathematical/physical equations. Result: Preliminary results concerning a different aspect of mitral valve leafletsbiomechanics, such as leaflets dynamics, displacements, thickness, stress and strain on leaflets. Conclusion: These data potentially allow the implementation of an image-based approach for patient-specific modeling of mitral valve leaflets. This approach could constitute the basis for accurate evaluation of mitral valve pathologic conditions and for the planning of surgical approaches.
    VL  - 2
    IS  - 2
    ER  - 

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Author Information
  • Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

  • Modarres Hospital, Institute of Cardiovascular Research, Shahid Beheshti University of Medical Sciences, Tehran, Iran

  • Modarres Hospital, Institute of Cardiovascular Research, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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