Clinical Medicine Research

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Adverse Effects of Whole Blood Donation among Voluntary Blood Donors in Jos, Nigeria

Received: 19 December 2014    Accepted: 04 January 2015    Published: 28 January 2015
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Abstract

Introduction: Despite collection of blood from apparently healthy individuals for allogeneic transfusion, blood givers are often faced with untoward reactions during or after blood donation. Aim: This study was to determine the rate of adverse reactions among voluntary blood donors at the National Blood Transfusion Service in Jos. Methods: All blood donors recruited by the centre between October 2012 and September 2014 were counseled and consent to participate in the research was obtained prior to donation. The age, sex, weight and blood pressure and the venue of donation were documented. The type of donation reaction during and or after donation were timed and documented. The haemoglobin level and haemoglobin phenotypes were determined. Results: Eleven thousand six hundred and fifty-five (63%) male and 37% females were studied. The overall rate of adverse effects was 2.05% with significantly higher rate of occurrence among donors aged 18-25 years (p˂0.0001), female donors (p=0.0001), weight 40-49 Kg (p=0.001), blood group B (p=0.002) haemoglobin phenotype AA (P=0.001). The rate of adverse reactions was also higher among first-time donors (p=0.002), indoor donations (p=0.001). All adverse effects documented in our donors occurred during donation (4%) and within 21 (96%) after donation. Dizziness affected 90% while severe reaction (faint) occurred in 3% of adverse reactors. Ingested meal was the vomits of all donors who vomited. Conclusion: Though adverse effects to blood donation is low in our centre, there is need for preparedness, donor education, prediction and mitigation of occurrences.

DOI 10.11648/j.cmr.20150401.12
Published in Clinical Medicine Research (Volume 4, Issue 1, January 2015)
Page(s) 6-10
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Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Adverse Effects, Voluntary, Blood Donation, Jos, Nigeria

References
[1] Newman BH, Pichette S, Pichette D et al. Adverse effects of blood donation. Transfus. 2003; 43: 598-603.
[2] Newman BH. Blood donor complications after whole blood donation. Current Opin Haematol. 2004; 11: 339-345.
[3] Newman BH. Whole blood donation: blood donor suitability and adverse events. Current haematol Rep. 2004; 3:437-443
[4] Newman BH, Roth AJ. Estimating the probability of a blood donation adverse event based on 1000 interviewed whole blood donors. Transfus. 2005; 45: 1715-1721
[5] Crocco A, D’Elia D. Adverse reactions during voluntary donation blood and/or blood components. A statistical epidemiological study. Blood transfus. 2007; 5: 153-152
[6] Pathak C, Pujani M, Pahuja S et al. Adverse reactions in whole blood donors: an Indian scenario. Blood transfuse. 2011; 9: 46-49
[7] Eder AF, Hillyer CD, Dy BA et al. Adverse reaction to allogeneic whole blood donation by 16 and 17 years old. JAMA. 2008; 299: 2279-2286
[8] Wiltbuk TB, Giordano GF, Kaniel H et al. Faints and prefaints reactions in whole blood donors: an analysis of pre-donation measurements and their predictive value. Transfus. 2008; 48: 1799-1808
[9] Javad H, Shashahani HJZ, Yavari MT. Adverse effects in blood donors after whole blood donation. Sci J Iranian Blood Transfus Org. 2007; 4: 87-93
[10] Symvaslakis EK, Vardavas CL, Fountouli P. Adverse reactions to blood donation among adolescents. JAMA. 2008; 300:1759-1760
[11] Mahbub-ul-Alam M, Hyder MS, Khan MBK et al. Adverse donor reaction during and immediately after venessection. TAJ. 2007; 20: 39-47
[12] Hosseini MJ, Latiff L, Syad Hassan ST et al. Comments on adverse reaction in blood donors. Blood Transfus. 2010; 8: 71
[13] Donic D, Lefort C. Serious adverse effects of blood collection. Transfus Clin Biol. 2010; 17: 301-305
[14] The National Blood Transfusion Service. The National Blood Policy. Federal Ministry of Health Abuja; 2006: 1-24.
[15] Soloren JT, Tuomainen T, Soloren R. Donation of blood is associated with reduced risk of myocardial infarction. AM J Epid. 1998; 48: 445-51
[16] Adediran Uche, E., Adediran, A., Damulak, O.D., Adeyemo, T., Akinbami, A. and Akanmu, A (2013). Lipid profile of regular blood donors. Journal of Blood Medicine. 4; 39-42.
[17] Calhoun L. Petz LD. Erythrocyte antigens and antibodies. In: Ernest B, Marshall AL, Barry SC, Thomas JK, Uri S (edds). Williams Haematology. 6th Edition, McGrwal Hill, New York, 2002: 1843-58.
[18] Beutler E. The sickle cell disease and related disorders. In: Ernest B, Marshall AL, Barry SC, Thomas JK, Uri S (edds). Williams Haematology. 6th Edition, McGrwal Hill, New York, 2002: 581-606.
[19] Kamal H, Tomosolu P, Bravo M et al. delayed adverse reactions to blood donation. Transfus. 2010; 50: 556-65
[20] Gridon AJ. Adverse reactions to whole blood donation and plasmapheresis. Crit Rev Clin Lab Sci. 1982; 17: 51-75
Author Information
  • Dept of Haematology & Blood Transfusion, Faculty of Medical Sciences, University of Jos, Jos, Nigeria

  • Dept of Haematology & Blood Transfusion, Faculty of Medical Sciences, University of Jos, Jos, Nigeria

  • National Blood Transfusion Service, North Central Zonal Centre, Jos, Nigeria

  • National Blood Transfusion Service, North Central Zonal Centre, Jos, Nigeria

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  • APA Style

    Damulak Obadiah Dapus, Egesie Ochaka Julie, Chetle Ladi, Thomas Margaret. (2015). Adverse Effects of Whole Blood Donation among Voluntary Blood Donors in Jos, Nigeria. Clinical Medicine Research, 4(1), 6-10. https://doi.org/10.11648/j.cmr.20150401.12

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    ACS Style

    Damulak Obadiah Dapus; Egesie Ochaka Julie; Chetle Ladi; Thomas Margaret. Adverse Effects of Whole Blood Donation among Voluntary Blood Donors in Jos, Nigeria. Clin. Med. Res. 2015, 4(1), 6-10. doi: 10.11648/j.cmr.20150401.12

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    AMA Style

    Damulak Obadiah Dapus, Egesie Ochaka Julie, Chetle Ladi, Thomas Margaret. Adverse Effects of Whole Blood Donation among Voluntary Blood Donors in Jos, Nigeria. Clin Med Res. 2015;4(1):6-10. doi: 10.11648/j.cmr.20150401.12

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  • @article{10.11648/j.cmr.20150401.12,
      author = {Damulak Obadiah Dapus and Egesie Ochaka Julie and Chetle Ladi and Thomas Margaret},
      title = {Adverse Effects of Whole Blood Donation among Voluntary Blood Donors in Jos, Nigeria},
      journal = {Clinical Medicine Research},
      volume = {4},
      number = {1},
      pages = {6-10},
      doi = {10.11648/j.cmr.20150401.12},
      url = {https://doi.org/10.11648/j.cmr.20150401.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.cmr.20150401.12},
      abstract = {Introduction: Despite collection of blood from apparently healthy individuals for allogeneic transfusion, blood givers are often faced with untoward reactions during or after blood donation. Aim: This study was to determine the rate of adverse reactions among voluntary blood donors at the National Blood Transfusion Service in Jos. Methods: All blood donors recruited by the centre between October 2012 and September 2014 were counseled and consent to participate in the research was obtained prior to donation. The age, sex, weight and blood pressure and the venue of donation were documented. The type of donation reaction during and or after donation were timed and documented. The haemoglobin level and haemoglobin phenotypes were determined. Results: Eleven thousand six hundred and fifty-five (63%) male and 37% females were studied. The overall rate of adverse effects was 2.05% with significantly higher rate of occurrence among donors aged 18-25 years (p˂0.0001), female donors (p=0.0001), weight 40-49 Kg (p=0.001), blood group B (p=0.002) haemoglobin phenotype AA (P=0.001). The rate of adverse reactions was also higher among first-time donors (p=0.002), indoor donations (p=0.001). All adverse effects documented in our donors occurred during donation (4%) and within 21 (96%) after donation. Dizziness affected 90% while severe reaction (faint) occurred in 3% of adverse reactors. Ingested meal was the vomits of all donors who vomited. Conclusion: Though adverse effects to blood donation is low in our centre, there is need for preparedness, donor education, prediction and mitigation of occurrences.},
     year = {2015}
    }
    

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  • TY  - JOUR
    T1  - Adverse Effects of Whole Blood Donation among Voluntary Blood Donors in Jos, Nigeria
    AU  - Damulak Obadiah Dapus
    AU  - Egesie Ochaka Julie
    AU  - Chetle Ladi
    AU  - Thomas Margaret
    Y1  - 2015/01/28
    PY  - 2015
    N1  - https://doi.org/10.11648/j.cmr.20150401.12
    DO  - 10.11648/j.cmr.20150401.12
    T2  - Clinical Medicine Research
    JF  - Clinical Medicine Research
    JO  - Clinical Medicine Research
    SP  - 6
    EP  - 10
    PB  - Science Publishing Group
    SN  - 2326-9057
    UR  - https://doi.org/10.11648/j.cmr.20150401.12
    AB  - Introduction: Despite collection of blood from apparently healthy individuals for allogeneic transfusion, blood givers are often faced with untoward reactions during or after blood donation. Aim: This study was to determine the rate of adverse reactions among voluntary blood donors at the National Blood Transfusion Service in Jos. Methods: All blood donors recruited by the centre between October 2012 and September 2014 were counseled and consent to participate in the research was obtained prior to donation. The age, sex, weight and blood pressure and the venue of donation were documented. The type of donation reaction during and or after donation were timed and documented. The haemoglobin level and haemoglobin phenotypes were determined. Results: Eleven thousand six hundred and fifty-five (63%) male and 37% females were studied. The overall rate of adverse effects was 2.05% with significantly higher rate of occurrence among donors aged 18-25 years (p˂0.0001), female donors (p=0.0001), weight 40-49 Kg (p=0.001), blood group B (p=0.002) haemoglobin phenotype AA (P=0.001). The rate of adverse reactions was also higher among first-time donors (p=0.002), indoor donations (p=0.001). All adverse effects documented in our donors occurred during donation (4%) and within 21 (96%) after donation. Dizziness affected 90% while severe reaction (faint) occurred in 3% of adverse reactors. Ingested meal was the vomits of all donors who vomited. Conclusion: Though adverse effects to blood donation is low in our centre, there is need for preparedness, donor education, prediction and mitigation of occurrences.
    VL  - 4
    IS  - 1
    ER  - 

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