Infrared Spectroscopic Study Dihydroquercetin and its New Substances with Benzoyl Chloride
Clinical Medicine Research
Volume 5, Issue 2-2, April 2016, Pages: 1-7
Received: Dec. 23, 2015; Accepted: Dec. 25, 2015; Published: Jun. 18, 2016
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Authors
А. К. Boshkayeva, Module "Pharmacist-analyst", Institute of Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty, The Republic of Kazakhstan
R. A. Omarova, Module "Pharmacist-analyst", Institute of Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty, The Republic of Kazakhstan
K. B. Zharimbetov, Module "Pharmacist-manager", Institute of Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty, The Republic of Kazakhstan
G. S. Ibadullayeva, Module "Pharmacist-technologist", Institute of Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty, The Republic of Kazakhstan
E. M. Bissenbaev, Module "Pharmacist-technologist", Institute of Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty, The Republic of Kazakhstan
K. K. Zhaldybaev, Joint Course of pharmacology and pharmacy, Kazakh-Russian Medical University, Almaty, The Republic of Kazakhstan
M. K. Iskakovа, Department of Internship of Dentistry, Institute of Stomatology, Asfendiyarov Kazakh National Medical University, Almaty, The Republic of Kazakhstan
Samir Anis Ross, National Scientific Center for Natural Products, University of Mississippi, Oxford, The United States
A. S. Kozhamzharovа, Module "Pharmacist-toxicologist", Institute of Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty, The Republic of Kazakhstan
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Abstract
The study acylation reactions of dihydroquercetin apart from scientific interest has practical value. As a result of the reactions will form new organic compounds which may possess potential antioxidant, anti-inflammatory and cytotoxic activity [1]. Within this research studying of processes of acylation of a dihydroquercetin with use of benzoyl chloride and definition of chemical structure of new medicinal substances, as homogeneous samples of high degree of purity was the important and interesting point. One of the promising methods of studying the structure of drug substances is the method of IR spectroscopy. The method gives the chance to make an objective assessment of authenticity that allows to use actively it in the pharmaceutical analysis of many unknown connections [2-4]. It predetermined conduct of the compulsory registration of IR spectra for the original dihydroquercetin and synthesized on its basis of new substances with benzoyl chloride.
Keywords
Dihydroquercetin, benzoyl chloride, identification, infrared spectroscopy, the State Pharmacopoeia of Republic Kazakhstan, synthesis
To cite this article
А. К. Boshkayeva, R. A. Omarova, K. B. Zharimbetov, G. S. Ibadullayeva, E. M. Bissenbaev, K. K. Zhaldybaev, M. K. Iskakovа, Samir Anis Ross, A. S. Kozhamzharovа, Infrared Spectroscopic Study Dihydroquercetin and its New Substances with Benzoyl Chloride, Clinical Medicine Research. Special Issue: Development of Drugs: Computer Simulation, Chemical Synthesis and Clinical Trials. Vol. 5, No. 2-2, 2016, pp. 1-7. doi: 10.11648/j.cmr.s.2016050202.11
Copyright
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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