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Effects of Yaji on Some Biochemical and Haematological Indices in Albino Wistar Rats

Received: 3 June 2019    Accepted: 9 August 2019    Published: 26 August 2019
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Abstract

Yaji is a mixture of spices and additives that is used as sauce for meat delicacy in Nigeria called suya. Its effects on the body weight, index of liver function, on lipid profile, kidney function and some haematological indices were the main focus of this study. A total of 50 Wistar rats with average weight of 200grams were randomly divided into five experimental groups: A, B, C, D and E. Each group consisted of ten animals. Baseline blood sample was collected from each animal. Group A was the control group while groups B to E were the treatment groups. Group A was given 100% chicken mesh, group B with 75% of chicken mesh + 25% of Yaji, group C with 50% of chicken mesh + 50% of Yaji, group D with 25% of chicken mesh + 75% of Yaji, group E with 100% of Yaji. The experiment lasted for 30days. There was a significant increase in some atherosclerotic index: Total Cholesterol (TC) and Triglyceride (TG), while the level of Low Density Lipoprotein (LDL) only increased at very high percentage of Yaji intake but High Density Lipoprotein (HDL) increased at moderate intake of Yaji. Sodium and Chloride ions were significantly increased while Potassium and Bicarbonate ions decreased significantly compared to the controls with urea and creatinine levels remaining unchanged. There was also a significant decrease in Packed Cell Volume (PCV) as the proportion of Yaji increased in relation to their feed while White Blood Cell Counts, total and differential were unchanged. The changes in weight did not show any statistical difference from the control. The consumption of the meat sauce, Yaji and its spices may have adverse health implications if consumed in higher quantity than the normal diet and therefore should be consumed only occasionally.

Published in Clinical Medicine Research (Volume 8, Issue 3)
DOI 10.11648/j.cmr.20190803.12
Page(s) 63-68
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Yaji, Aspartate and Alanine Amino Transferases, Alkaline Phosphatase, Total Cholesterol, High Density Lipoprotein, Low Density Lipoprotein, Serum Electrolytes, Urea and Creatinine

References
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Cite This Article
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    Chilaka Ugochinyere Jane, Chilaka Kingsley Chimsorom, Meludu Samuel, Chukwu Leoclincton. (2019). Effects of Yaji on Some Biochemical and Haematological Indices in Albino Wistar Rats. Clinical Medicine Research, 8(3), 63-68. https://doi.org/10.11648/j.cmr.20190803.12

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    ACS Style

    Chilaka Ugochinyere Jane; Chilaka Kingsley Chimsorom; Meludu Samuel; Chukwu Leoclincton. Effects of Yaji on Some Biochemical and Haematological Indices in Albino Wistar Rats. Clin. Med. Res. 2019, 8(3), 63-68. doi: 10.11648/j.cmr.20190803.12

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    AMA Style

    Chilaka Ugochinyere Jane, Chilaka Kingsley Chimsorom, Meludu Samuel, Chukwu Leoclincton. Effects of Yaji on Some Biochemical and Haematological Indices in Albino Wistar Rats. Clin Med Res. 2019;8(3):63-68. doi: 10.11648/j.cmr.20190803.12

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  • @article{10.11648/j.cmr.20190803.12,
      author = {Chilaka Ugochinyere Jane and Chilaka Kingsley Chimsorom and Meludu Samuel and Chukwu Leoclincton},
      title = {Effects of Yaji on Some Biochemical and Haematological Indices in Albino Wistar Rats},
      journal = {Clinical Medicine Research},
      volume = {8},
      number = {3},
      pages = {63-68},
      doi = {10.11648/j.cmr.20190803.12},
      url = {https://doi.org/10.11648/j.cmr.20190803.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20190803.12},
      abstract = {Yaji is a mixture of spices and additives that is used as sauce for meat delicacy in Nigeria called suya. Its effects on the body weight, index of liver function, on lipid profile, kidney function and some haematological indices were the main focus of this study. A total of 50 Wistar rats with average weight of 200grams were randomly divided into five experimental groups: A, B, C, D and E. Each group consisted of ten animals. Baseline blood sample was collected from each animal. Group A was the control group while groups B to E were the treatment groups. Group A was given 100% chicken mesh, group B with 75% of chicken mesh + 25% of Yaji, group C with 50% of chicken mesh + 50% of Yaji, group D with 25% of chicken mesh + 75% of Yaji, group E with 100% of Yaji. The experiment lasted for 30days. There was a significant increase in some atherosclerotic index: Total Cholesterol (TC) and Triglyceride (TG), while the level of Low Density Lipoprotein (LDL) only increased at very high percentage of Yaji intake but High Density Lipoprotein (HDL) increased at moderate intake of Yaji. Sodium and Chloride ions were significantly increased while Potassium and Bicarbonate ions decreased significantly compared to the controls with urea and creatinine levels remaining unchanged. There was also a significant decrease in Packed Cell Volume (PCV) as the proportion of Yaji increased in relation to their feed while White Blood Cell Counts, total and differential were unchanged. The changes in weight did not show any statistical difference from the control. The consumption of the meat sauce, Yaji and its spices may have adverse health implications if consumed in higher quantity than the normal diet and therefore should be consumed only occasionally.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Effects of Yaji on Some Biochemical and Haematological Indices in Albino Wistar Rats
    AU  - Chilaka Ugochinyere Jane
    AU  - Chilaka Kingsley Chimsorom
    AU  - Meludu Samuel
    AU  - Chukwu Leoclincton
    Y1  - 2019/08/26
    PY  - 2019
    N1  - https://doi.org/10.11648/j.cmr.20190803.12
    DO  - 10.11648/j.cmr.20190803.12
    T2  - Clinical Medicine Research
    JF  - Clinical Medicine Research
    JO  - Clinical Medicine Research
    SP  - 63
    EP  - 68
    PB  - Science Publishing Group
    SN  - 2326-9057
    UR  - https://doi.org/10.11648/j.cmr.20190803.12
    AB  - Yaji is a mixture of spices and additives that is used as sauce for meat delicacy in Nigeria called suya. Its effects on the body weight, index of liver function, on lipid profile, kidney function and some haematological indices were the main focus of this study. A total of 50 Wistar rats with average weight of 200grams were randomly divided into five experimental groups: A, B, C, D and E. Each group consisted of ten animals. Baseline blood sample was collected from each animal. Group A was the control group while groups B to E were the treatment groups. Group A was given 100% chicken mesh, group B with 75% of chicken mesh + 25% of Yaji, group C with 50% of chicken mesh + 50% of Yaji, group D with 25% of chicken mesh + 75% of Yaji, group E with 100% of Yaji. The experiment lasted for 30days. There was a significant increase in some atherosclerotic index: Total Cholesterol (TC) and Triglyceride (TG), while the level of Low Density Lipoprotein (LDL) only increased at very high percentage of Yaji intake but High Density Lipoprotein (HDL) increased at moderate intake of Yaji. Sodium and Chloride ions were significantly increased while Potassium and Bicarbonate ions decreased significantly compared to the controls with urea and creatinine levels remaining unchanged. There was also a significant decrease in Packed Cell Volume (PCV) as the proportion of Yaji increased in relation to their feed while White Blood Cell Counts, total and differential were unchanged. The changes in weight did not show any statistical difference from the control. The consumption of the meat sauce, Yaji and its spices may have adverse health implications if consumed in higher quantity than the normal diet and therefore should be consumed only occasionally.
    VL  - 8
    IS  - 3
    ER  - 

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Author Information
  • Department of Haematology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria

  • Department of Pharmacology, Nnamdi Azikiwe University, NnewiCampus, Nnewi, Nigeria

  • Department of Biochemistry, Nnamdi Azikiwe University, Okofia Campus, Nnewi, Nigeria

  • Department of Pharmacology and Therapeutics, Chukwuemeka Odumegwu Ojukwu University, Awka Campus, Awka, Nigeria

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