Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule

Vijay Kumar Sharma; Antony Abraham Paulose; Parvendra Singh; Nishi Sonkhya

doi:doi:10.11648/j.cmr.20190801.11

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Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule

Vijay Kumar Sharma, Antony Abraham Paulose, Parvendra Singh, Nishi Sonkhya

Received: 26 April 2018 Accepted: 14 May 2018 Published: 25 February 2019

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Abstract

Objective: In patients with solitary thyroid nodules, first approach is to confirm whether the nodule is benign or malignant. Commonly available investigations used in the evaluation include thyroid hormone assays, fine needle aspiration cytology (FNAC) and ultrasonography (USG) among others. These procedures are not without drawbacks. The present study was undertaken to compare the diagnostic efficacy of USG and FNAC in correlation with histopathology in euthyroid patients having solitary thyroid nodule. Study Design: A prospective study was carried out on 48 euthyroid cases of solitary thyroid nodule attending the Department of ENT, SMS Medical College & Hospital, Jaipur, during the period of March 2016 to November 2017. All patients underwent ultrasonography and fine-needle aspiration cytology. The results of FNAC and USG were correlated with post surgical histopathogical examination (HPE) of the specimens to evaluate their sensitivity and specificity by statistical methods. Results: Ultrasound was 87.5% sensitive & 92.50% specific in the detection of malignancy in solitary thyroid nodules while the fine needle aspiration cytology had a sensitivity of 87.50% & specificity of 100% in the same regard. Conclusion: It was found that FNAC is a safe, reliable and cost effective diagnostic modality with a high sensitivity and specificity and is the single best investigation for preoperative evaluation of solitary thyroid nodule to differentiate between benign and malignancy nodules.

DOI	10.11648/j.cmr.20190801.11
Published in	Clinical Medicine Research (Volume 8, Issue 1, January 2019)
Page(s)	1-5
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

STN, USG, FNAC, Thyroid Malignancy

References

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APA Style

Vijay Kumar Sharma, Antony Abraham Paulose, Parvendra Singh, Nishi Sonkhya. (2019). Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule. Clinical Medicine Research, 8(1), 1-5. https://doi.org/10.11648/j.cmr.20190801.11

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ACS Style

Vijay Kumar Sharma; Antony Abraham Paulose; Parvendra Singh; Nishi Sonkhya. Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule. Clin. Med. Res. 2019, 8(1), 1-5. doi: 10.11648/j.cmr.20190801.11

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AMA Style

Vijay Kumar Sharma, Antony Abraham Paulose, Parvendra Singh, Nishi Sonkhya. Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule. Clin Med Res. 2019;8(1):1-5. doi: 10.11648/j.cmr.20190801.11

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@article{10.11648/j.cmr.20190801.11,
  author = {Vijay Kumar Sharma and Antony Abraham Paulose and Parvendra Singh and Nishi Sonkhya},
  title = {Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule},
  journal = {Clinical Medicine Research},
  volume = {8},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.cmr.20190801.11},
  url = {https://doi.org/10.11648/j.cmr.20190801.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20190801.11},
  abstract = {Objective: In patients with solitary thyroid nodules, first approach is to confirm whether the nodule is benign or malignant. Commonly available investigations used in the evaluation include thyroid hormone assays, fine needle aspiration cytology (FNAC) and ultrasonography (USG) among others. These procedures are not without drawbacks. The present study was undertaken to compare the diagnostic efficacy of USG and FNAC in correlation with histopathology in euthyroid patients having solitary thyroid nodule. Study Design: A prospective study was carried out on 48 euthyroid cases of solitary thyroid nodule attending the Department of ENT, SMS Medical College & Hospital, Jaipur, during the period of March 2016 to November 2017. All patients underwent ultrasonography and fine-needle aspiration cytology. The results of FNAC and USG were correlated with post surgical histopathogical examination (HPE) of the specimens to evaluate their sensitivity and specificity by statistical methods. Results: Ultrasound was 87.5% sensitive & 92.50% specific in the detection of malignancy in solitary thyroid nodules while the fine needle aspiration cytology had a sensitivity of 87.50% & specificity of 100% in the same regard. Conclusion: It was found that FNAC is a safe, reliable and cost effective diagnostic modality with a high sensitivity and specificity and is the single best investigation for preoperative evaluation of solitary thyroid nodule to differentiate between benign and malignancy nodules.},
 year = {2019}
}

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TY  - JOUR
T1  - Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule
AU  - Vijay Kumar Sharma
AU  - Antony Abraham Paulose
AU  - Parvendra Singh
AU  - Nishi Sonkhya
Y1  - 2019/02/25
PY  - 2019
N1  - https://doi.org/10.11648/j.cmr.20190801.11
DO  - 10.11648/j.cmr.20190801.11
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 1
EP  - 5
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20190801.11
AB  - Objective: In patients with solitary thyroid nodules, first approach is to confirm whether the nodule is benign or malignant. Commonly available investigations used in the evaluation include thyroid hormone assays, fine needle aspiration cytology (FNAC) and ultrasonography (USG) among others. These procedures are not without drawbacks. The present study was undertaken to compare the diagnostic efficacy of USG and FNAC in correlation with histopathology in euthyroid patients having solitary thyroid nodule. Study Design: A prospective study was carried out on 48 euthyroid cases of solitary thyroid nodule attending the Department of ENT, SMS Medical College & Hospital, Jaipur, during the period of March 2016 to November 2017. All patients underwent ultrasonography and fine-needle aspiration cytology. The results of FNAC and USG were correlated with post surgical histopathogical examination (HPE) of the specimens to evaluate their sensitivity and specificity by statistical methods. Results: Ultrasound was 87.5% sensitive & 92.50% specific in the detection of malignancy in solitary thyroid nodules while the fine needle aspiration cytology had a sensitivity of 87.50% & specificity of 100% in the same regard. Conclusion: It was found that FNAC is a safe, reliable and cost effective diagnostic modality with a high sensitivity and specificity and is the single best investigation for preoperative evaluation of solitary thyroid nodule to differentiate between benign and malignancy nodules.
VL  - 8
IS  - 1
ER  -

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Author Information

Vijay Kumar Sharma

Department of Otorhinolaryngology and Head and Neck surgery, Sawai Man Singh Medical College, Jaipur, India
Antony Abraham Paulose

Department of Otorhinolaryngology and Head and Neck surgery, Sawai Man Singh Medical College, Jaipur, India
Parvendra Singh

Department of Otorhinolaryngology and Head and Neck surgery, Sawai Man Singh Medical College, Jaipur, India
Nishi Sonkhya

Department of Otorhinolaryngology and Head and Neck surgery, Sawai Man Singh Medical College, Jaipur, India

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APA Style

Vijay Kumar Sharma, Antony Abraham Paulose, Parvendra Singh, Nishi Sonkhya. (2019). Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule. Clinical Medicine Research, 8(1), 1-5. https://doi.org/10.11648/j.cmr.20190801.11

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ACS Style

Vijay Kumar Sharma; Antony Abraham Paulose; Parvendra Singh; Nishi Sonkhya. Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule. Clin. Med. Res. 2019, 8(1), 1-5. doi: 10.11648/j.cmr.20190801.11

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AMA Style

Vijay Kumar Sharma, Antony Abraham Paulose, Parvendra Singh, Nishi Sonkhya. Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule. Clin Med Res. 2019;8(1):1-5. doi: 10.11648/j.cmr.20190801.11

Copy | Download

@article{10.11648/j.cmr.20190801.11,
  author = {Vijay Kumar Sharma and Antony Abraham Paulose and Parvendra Singh and Nishi Sonkhya},
  title = {Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule},
  journal = {Clinical Medicine Research},
  volume = {8},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.cmr.20190801.11},
  url = {https://doi.org/10.11648/j.cmr.20190801.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20190801.11},
  abstract = {Objective: In patients with solitary thyroid nodules, first approach is to confirm whether the nodule is benign or malignant. Commonly available investigations used in the evaluation include thyroid hormone assays, fine needle aspiration cytology (FNAC) and ultrasonography (USG) among others. These procedures are not without drawbacks. The present study was undertaken to compare the diagnostic efficacy of USG and FNAC in correlation with histopathology in euthyroid patients having solitary thyroid nodule. Study Design: A prospective study was carried out on 48 euthyroid cases of solitary thyroid nodule attending the Department of ENT, SMS Medical College & Hospital, Jaipur, during the period of March 2016 to November 2017. All patients underwent ultrasonography and fine-needle aspiration cytology. The results of FNAC and USG were correlated with post surgical histopathogical examination (HPE) of the specimens to evaluate their sensitivity and specificity by statistical methods. Results: Ultrasound was 87.5% sensitive & 92.50% specific in the detection of malignancy in solitary thyroid nodules while the fine needle aspiration cytology had a sensitivity of 87.50% & specificity of 100% in the same regard. Conclusion: It was found that FNAC is a safe, reliable and cost effective diagnostic modality with a high sensitivity and specificity and is the single best investigation for preoperative evaluation of solitary thyroid nodule to differentiate between benign and malignancy nodules.},
 year = {2019}
}

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TY  - JOUR
T1  - Diagnostic Efficacy of Ultrasonography and Fine-needle Aspiration Cytology in Correlation with Histopathology in Euthyroid Patients Having Solitary Thyroid Nodule
AU  - Vijay Kumar Sharma
AU  - Antony Abraham Paulose
AU  - Parvendra Singh
AU  - Nishi Sonkhya
Y1  - 2019/02/25
PY  - 2019
N1  - https://doi.org/10.11648/j.cmr.20190801.11
DO  - 10.11648/j.cmr.20190801.11
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 1
EP  - 5
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20190801.11
AB  - Objective: In patients with solitary thyroid nodules, first approach is to confirm whether the nodule is benign or malignant. Commonly available investigations used in the evaluation include thyroid hormone assays, fine needle aspiration cytology (FNAC) and ultrasonography (USG) among others. These procedures are not without drawbacks. The present study was undertaken to compare the diagnostic efficacy of USG and FNAC in correlation with histopathology in euthyroid patients having solitary thyroid nodule. Study Design: A prospective study was carried out on 48 euthyroid cases of solitary thyroid nodule attending the Department of ENT, SMS Medical College & Hospital, Jaipur, during the period of March 2016 to November 2017. All patients underwent ultrasonography and fine-needle aspiration cytology. The results of FNAC and USG were correlated with post surgical histopathogical examination (HPE) of the specimens to evaluate their sensitivity and specificity by statistical methods. Results: Ultrasound was 87.5% sensitive & 92.50% specific in the detection of malignancy in solitary thyroid nodules while the fine needle aspiration cytology had a sensitivity of 87.50% & specificity of 100% in the same regard. Conclusion: It was found that FNAC is a safe, reliable and cost effective diagnostic modality with a high sensitivity and specificity and is the single best investigation for preoperative evaluation of solitary thyroid nodule to differentiate between benign and malignancy nodules.
VL  - 8
IS  - 1
ER  -

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