Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder

Guotao Fang; Qi Zhang

doi:doi:10.11648/j.cmr.20170603.19

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Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder

Guotao Fang, Qi Zhang

Published in Clinical Medicine Research (Volume 6, Issue 3)

Received: 4 May 2017 Accepted: Published: 4 May 2017

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Abstract

To discuss the effects of different treatment methods on the prognosis of primary carcinoma of gallbladder (PCG) patients. The clinical statistics of 99 cases of PCG patients were retrospectively analyzed, and the prognosis multivariate analysis was performed. Results: 52% of the patients suffered from PCG and gallstones simultaneously, and 82.8% (82/99) of the patients were diagnosed as PCG before surgeries. 86 cases of patients were subjected to routine exploratory surgeryies, and the radical resection rate was 33.72% (29/86). The overall 5-year survival rate was 6.28%, and the 1-year, 3-year and 5-year survival rates of the radical resection group were 78.43%, 48.49% and 23.77%, respectively. The results were significantly different from those of the palliative surgery group, the exploratory laparotomy group and the non-surgical group. The multivariate analysis of Cox model reveals that surgical method was significantly correlated with the invasion depth of tumor and the prognosis of gallbladder carcinoma. The treatment efficacy of PCG might be improved by increasing the early diagnosis rate and performing radical resection which are accompanied by radiotherapy and chemotherapy.

Published in	Clinical Medicine Research (Volume 6, Issue 3)
DOI	10.11648/j.cmr.20170603.19
Page(s)	111-115
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Gallbladder Tumor, Surgery, Prognostic Factor

References

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[3]	Kim K, Chie EK,et al. Postoperative chemoradiotherapy for gallbladder carcinoma [J].Strahlenther Onkol, 2012, 188 (5): 388-92.
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[8]	Giang TH, Ngoc TT, Hassell LA. Carcinoma involving the gallbladder: a retrospective review of 23 cases - pitfalls in diagnosis of gallbladder carcinoma [J]. Diagn Pathol, 2012, 27 (7): 10-11.
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[10]	Konstantinidis IT, Bajpai S,et al. Gallbladder lesions identified on ultrasound. Lessons from the last 10 years [J]. J Gastrointest Surg, 2012, 16 (3): 549-53.
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[13]	Choi SB, Han HJ, et al. Fourteen year surgical experience of gallbladder carcinoma: validity of curative resection affecting survival [J]. Hepatogastroenterology, 2012, 59 (113): 36-41.
[14]	Wang SJ, Lemieux A, et al. Nomogram for predicting the benefit of adjuvant chemoradiotherapy for resectedgallbladder carcinoma [J]. J Clin Oncol, 2011, 29 (35): 4627-32.

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Guotao Fang, Qi Zhang. (2017). Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder. Clinical Medicine Research, 6(3), 111-115. https://doi.org/10.11648/j.cmr.20170603.19

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ACS Style

Guotao Fang; Qi Zhang. Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder. Clin. Med. Res. 2017, 6(3), 111-115. doi: 10.11648/j.cmr.20170603.19

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AMA Style

Guotao Fang, Qi Zhang. Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder. Clin Med Res. 2017;6(3):111-115. doi: 10.11648/j.cmr.20170603.19

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@article{10.11648/j.cmr.20170603.19,
  author = {Guotao Fang and Qi Zhang},
  title = {Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder},
  journal = {Clinical Medicine Research},
  volume = {6},
  number = {3},
  pages = {111-115},
  doi = {10.11648/j.cmr.20170603.19},
  url = {https://doi.org/10.11648/j.cmr.20170603.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20170603.19},
  abstract = {To discuss the effects of different treatment methods on the prognosis of primary carcinoma of gallbladder (PCG) patients. The clinical statistics of 99 cases of PCG patients were retrospectively analyzed, and the prognosis multivariate analysis was performed. Results: 52% of the patients suffered from PCG and gallstones simultaneously, and 82.8% (82/99) of the patients were diagnosed as PCG before surgeries. 86 cases of patients were subjected to routine exploratory surgeryies, and the radical resection rate was 33.72% (29/86). The overall 5-year survival rate was 6.28%, and the 1-year, 3-year and 5-year survival rates of the radical resection group were 78.43%, 48.49% and 23.77%, respectively. The results were significantly different from those of the palliative surgery group, the exploratory laparotomy group and the non-surgical group. The multivariate analysis of Cox model reveals that surgical method was significantly correlated with the invasion depth of tumor and the prognosis of gallbladder carcinoma. The treatment efficacy of PCG might be improved by increasing the early diagnosis rate and performing radical resection which are accompanied by radiotherapy and chemotherapy.},
 year = {2017}
}

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TY  - JOUR
T1  - Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder
AU  - Guotao Fang
AU  - Qi Zhang
Y1  - 2017/05/04
PY  - 2017
N1  - https://doi.org/10.11648/j.cmr.20170603.19
DO  - 10.11648/j.cmr.20170603.19
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 111
EP  - 115
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20170603.19
AB  - To discuss the effects of different treatment methods on the prognosis of primary carcinoma of gallbladder (PCG) patients. The clinical statistics of 99 cases of PCG patients were retrospectively analyzed, and the prognosis multivariate analysis was performed. Results: 52% of the patients suffered from PCG and gallstones simultaneously, and 82.8% (82/99) of the patients were diagnosed as PCG before surgeries. 86 cases of patients were subjected to routine exploratory surgeryies, and the radical resection rate was 33.72% (29/86). The overall 5-year survival rate was 6.28%, and the 1-year, 3-year and 5-year survival rates of the radical resection group were 78.43%, 48.49% and 23.77%, respectively. The results were significantly different from those of the palliative surgery group, the exploratory laparotomy group and the non-surgical group. The multivariate analysis of Cox model reveals that surgical method was significantly correlated with the invasion depth of tumor and the prognosis of gallbladder carcinoma. The treatment efficacy of PCG might be improved by increasing the early diagnosis rate and performing radical resection which are accompanied by radiotherapy and chemotherapy.
VL  - 6
IS  - 3
ER  -

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Author Information

Guotao Fang

The Second Ward Department of Oncology, Affiliated Hospital of Hebei University, Baoding, P. R. China
Qi Zhang

Department of Clinical Medicine, Medical College of HeBei University, Baoding, P. R. China

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Plain Text BibTeX RIS

APA Style

Guotao Fang, Qi Zhang. (2017). Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder. Clinical Medicine Research, 6(3), 111-115. https://doi.org/10.11648/j.cmr.20170603.19

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ACS Style

Guotao Fang; Qi Zhang. Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder. Clin. Med. Res. 2017, 6(3), 111-115. doi: 10.11648/j.cmr.20170603.19

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AMA Style

Guotao Fang, Qi Zhang. Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder. Clin Med Res. 2017;6(3):111-115. doi: 10.11648/j.cmr.20170603.19

Copy | Download

@article{10.11648/j.cmr.20170603.19,
  author = {Guotao Fang and Qi Zhang},
  title = {Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder},
  journal = {Clinical Medicine Research},
  volume = {6},
  number = {3},
  pages = {111-115},
  doi = {10.11648/j.cmr.20170603.19},
  url = {https://doi.org/10.11648/j.cmr.20170603.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20170603.19},
  abstract = {To discuss the effects of different treatment methods on the prognosis of primary carcinoma of gallbladder (PCG) patients. The clinical statistics of 99 cases of PCG patients were retrospectively analyzed, and the prognosis multivariate analysis was performed. Results: 52% of the patients suffered from PCG and gallstones simultaneously, and 82.8% (82/99) of the patients were diagnosed as PCG before surgeries. 86 cases of patients were subjected to routine exploratory surgeryies, and the radical resection rate was 33.72% (29/86). The overall 5-year survival rate was 6.28%, and the 1-year, 3-year and 5-year survival rates of the radical resection group were 78.43%, 48.49% and 23.77%, respectively. The results were significantly different from those of the palliative surgery group, the exploratory laparotomy group and the non-surgical group. The multivariate analysis of Cox model reveals that surgical method was significantly correlated with the invasion depth of tumor and the prognosis of gallbladder carcinoma. The treatment efficacy of PCG might be improved by increasing the early diagnosis rate and performing radical resection which are accompanied by radiotherapy and chemotherapy.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder
AU  - Guotao Fang
AU  - Qi Zhang
Y1  - 2017/05/04
PY  - 2017
N1  - https://doi.org/10.11648/j.cmr.20170603.19
DO  - 10.11648/j.cmr.20170603.19
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 111
EP  - 115
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20170603.19
AB  - To discuss the effects of different treatment methods on the prognosis of primary carcinoma of gallbladder (PCG) patients. The clinical statistics of 99 cases of PCG patients were retrospectively analyzed, and the prognosis multivariate analysis was performed. Results: 52% of the patients suffered from PCG and gallstones simultaneously, and 82.8% (82/99) of the patients were diagnosed as PCG before surgeries. 86 cases of patients were subjected to routine exploratory surgeryies, and the radical resection rate was 33.72% (29/86). The overall 5-year survival rate was 6.28%, and the 1-year, 3-year and 5-year survival rates of the radical resection group were 78.43%, 48.49% and 23.77%, respectively. The results were significantly different from those of the palliative surgery group, the exploratory laparotomy group and the non-surgical group. The multivariate analysis of Cox model reveals that surgical method was significantly correlated with the invasion depth of tumor and the prognosis of gallbladder carcinoma. The treatment efficacy of PCG might be improved by increasing the early diagnosis rate and performing radical resection which are accompanied by radiotherapy and chemotherapy.
VL  - 6
IS  - 3
ER  -

Copy | Download