Vitiligo and Treatment
Clinical Medicine Research
Volume 4, Issue 6, November 2015, Pages: 195-197
Received: Aug. 31, 2015; Accepted: Nov. 9, 2015; Published: Dec. 3, 2015
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Authors
Sadije Halimi, Department of Dermatovenerology, University Clinical Centre of Kosovo, Pristina, Republic of Kosovo
Mybera Ferizi, Department of Dermatovenerology, University Clinical Centre of Kosovo, Pristina, Republic of Kosovo
Antigona Gerqari, Department of Dermatovenerology, University Clinical Centre of Kosovo, Pristina, Republic of Kosovo
Nita Krasniqi, University of Prishtina, Medical Faculty, Pristina, Republic of Kosovo
Mergita Ferizi, University of Prishtina, Medical Faculty, Pristina, Republic of Kosovo
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Abstract
Background: Vitiligo is a common skin condition resulting from loss of normal melanin pigments in the skin which produces white patches. It mainly affects a younger population and can cause serious cosmetic and social problems. At least three theories about the underlying mechanism of vitiligo have been proposed. Release of a chemical that is toxic to melanocytes is one theory, while another theory says that the melanocytes simply self-destruct. According to the third theory, vitiligo is a type of autoimmune disease. Methods: We performed a prospective study to evaluate the efficacy of the 0.05% clobetasol propionate and 1% pimecrolimus in the treatment of vitiligo. In our study is 25 patients with virtually lesions of vitiligo. Results: Results from this pilot study indicate that topical 1% pimecrolimus is as effective as clobetasol propionate in restoring skin disfiguring due to vitiligo. Discussion: Further studies investigating the safety and efficacy of topical 1% pimecrolimus ointment either as monotherapy or in combination with other therapeutic measures are warranted.
Keywords
Vitiligo, the Skin Dispigmentation, Progress in Treatment of Vitiligo
To cite this article
Sadije Halimi, Mybera Ferizi, Antigona Gerqari, Nita Krasniqi, Mergita Ferizi, Vitiligo and Treatment, Clinical Medicine Research. Vol. 4, No. 6, 2015, pp. 195-197. doi: 10.11648/j.cmr.20150406.15
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