Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study
Clinical Medicine Research
Volume 3, Issue 2, March 2014, Pages: 17-20
Received: Jan. 6, 2014;
Published: Feb. 20, 2014
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Sukdeb Biswas, Department of Pathology, Nilratan Sircar Medical College and Hospital, Kolkata, India
Kaushik Ghosh, Department of Medicine, Malda Medical College and Hospital, Malda, India
Sisir Chakraborty, Department of Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata, India
Rajdip Hazra, Department of Anesthesiology, Nilratan Sircar Medical College and Hospital, Kolkata, India
Rabindra Nath Biswas, Department of Dermatology, Murshidabad Medical College and Hospital, Berhampore, India
Susmita Ghosh, Department of Anesthesiology, Bangur Institute of Neurosciences, Kolkata, India
Kaushik Das, Department of Medicine, Malda Medical College and Hospital, Malda, India
Niladri Sarkar, Department of Medicine, Burdwan Medical College, Burdwan, India
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Introduction: Cervical lymphadenoparthy is a common presentation of many diseases, though it is mostly tubercular in origin in developing countries. This cross sectional study was done to corroborate fine needle aspiration cytology (FNAC) findings with histopathological examinations (HPE) in cervical lymphadenopathy. Materials and methods: 120 patients of both sexes attending the FNAC unit of Nilratan Sircar Medical College and Hospital, Kolkata were enrolled in this study. They were evaluated by thorough clinical examination followed by routine investigations, FNAC and histopathological examination (HPE). Results: There was maximum corroboration of FNAC and HPE reports in tubercular lymphadenitis (76 v/s 76) and Hodgkin’s disease (2 v/s 2) followed by metastatic carcinoma (20 v/s 16) and non specific lymphadenitis (14 v/s 5) respectively. Overall correlation was 88.4% (excluding 8 cases where FNAC results were inconclusive due to unsatisfactory smear). The sensitivity, specificity, positive predictive value and negative predictive value of FNAC to diagnose tubercular lymphadenopathies were 86.36%. 100.0%, 100.0% and 72.73% respectively. In case of metastatic CA, these were 100.0%, 96.15%, 80.0% and 100.0% respectively. Conclusion: FNAC is simple, safe, quick, cheap, acceptable yet accurate method of establishing the etiology in cases of cervical lymphadenopathy.
Cervical Lymphadenopathy, Fine Needle Aspiration Cytology, Histopathology
To cite this article
Rabindra Nath Biswas,
Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study, Clinical Medicine Research.
Vol. 3, No. 2,
2014, pp. 17-20.
Abrari A, Ahmad S S, Bakshi V. Cytology in the otolaryngologist's domain- a study of 150 cases, emphasizing diagnostic utility and pitfalls. Indian J Otolaryngol Head Neck Surg. 2002;54(2):107-10.
Young JE, Archibald SD, Shier KJ. Needle aspiration cytologic biopsy in head and neck masses. Am J Surg. 1981;142(4):484-9.
Mahbod G, Koasri F, Tafreshi MA. Fine needle aspiration cytology in diagnosis of nonthyroidal neck masses. Acta Medica Iranica. 2002;40(1):49-51.
Pandit AA, Candes FB, Khubchandhani SR. Fine needle aspiration cytology of lymph nodes. J Postgrad Med. 1987;33(3):134-6.
Carroll CM, Nazeer U, Timon CI. The accuracy of fine -needle aspiration biopsy in the diagnosis of head and neck masses. Ir J Med sci. 1998;167(3):149-51.
Bardales RH, Baker SJ, Mukunyadzi P. Fine- needle aspiration cytology findings in 214 cases of nonparotid lesion of the head. Diagn cytopathol. 2000;22(4):211-7.
Khiery J, Ahmed ME. Cervical lymphadenopathy in Khartoum. JTrop Med Hyg. I992;95(6):416-9.
AL-Khafaji BM, NestokBR, Katz RL. Fine needle aspiration of 154 parotid masses with histologic correlation: Ten -year experience at the university of Texas M.D.Anderson cancer center. Cancer. 1998;84(3):153-9.
Djupesland P, Sauer T, Ferng A. Puncture cytology in tumours of the head and neck region. Tidsskr Nor Laegeforen. 1993;113(16):1985-7.
Patt BS, Schaefer SD, Vuitch F. Role of fine-needle aspiration in the evaluation of neck masses. Med Clin North Am. 1993;77(3):611-23
McGuirt WF, McCabe BF. Significance of node biopsy before definitive treatment of cervical metastatic carcinoma. Laryngoscope. 1978;88(4):594-7.