Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study
Clinical Medicine Research
Volume 3, Issue 2, March 2014, Pages: 17-20
Received: Jan. 6, 2014; Published: Feb. 20, 2014
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Authors
Sukdeb Biswas, Department of Pathology, Nilratan Sircar Medical College and Hospital, Kolkata, India
Kaushik Ghosh, Department of Medicine, Malda Medical College and Hospital, Malda, India
Sisir Chakraborty, Department of Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata, India
Rajdip Hazra, Department of Anesthesiology, Nilratan Sircar Medical College and Hospital, Kolkata, India
Rabindra Nath Biswas, Department of Dermatology, Murshidabad Medical College and Hospital, Berhampore, India
Susmita Ghosh, Department of Anesthesiology, Bangur Institute of Neurosciences, Kolkata, India
Kaushik Das, Department of Medicine, Malda Medical College and Hospital, Malda, India
Niladri Sarkar, Department of Medicine, Burdwan Medical College, Burdwan, India
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Abstract
Introduction: Cervical lymphadenoparthy is a common presentation of many diseases, though it is mostly tubercular in origin in developing countries. This cross sectional study was done to corroborate fine needle aspiration cytology (FNAC) findings with histopathological examinations (HPE) in cervical lymphadenopathy. Materials and methods: 120 patients of both sexes attending the FNAC unit of Nilratan Sircar Medical College and Hospital, Kolkata were enrolled in this study. They were evaluated by thorough clinical examination followed by routine investigations, FNAC and histopathological examination (HPE). Results: There was maximum corroboration of FNAC and HPE reports in tubercular lymphadenitis (76 v/s 76) and Hodgkin’s disease (2 v/s 2) followed by metastatic carcinoma (20 v/s 16) and non specific lymphadenitis (14 v/s 5) respectively. Overall correlation was 88.4% (excluding 8 cases where FNAC results were inconclusive due to unsatisfactory smear). The sensitivity, specificity, positive predictive value and negative predictive value of FNAC to diagnose tubercular lymphadenopathies were 86.36%. 100.0%, 100.0% and 72.73% respectively. In case of metastatic CA, these were 100.0%, 96.15%, 80.0% and 100.0% respectively. Conclusion: FNAC is simple, safe, quick, cheap, acceptable yet accurate method of establishing the etiology in cases of cervical lymphadenopathy.
Keywords
Cervical Lymphadenopathy, Fine Needle Aspiration Cytology, Histopathology
To cite this article
Sukdeb Biswas, Kaushik Ghosh, Sisir Chakraborty, Rajdip Hazra, Rabindra Nath Biswas, Susmita Ghosh, Kaushik Das, Niladri Sarkar, Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study, Clinical Medicine Research. Vol. 3, No. 2, 2014, pp. 17-20. doi: 10.11648/j.cmr.20140302.12
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