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Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones

Received: 11 August 2014    Accepted: 18 August 2014    Published: 30 August 2014
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Abstract

The synthesis and characterization of copper(II) complexes with 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one thiosemicarbazone and N(4)-substituted thiosemicarbazones are reported. Elemental analysis, molar conductivities, magnetic measurements and spectral (i.r., electronic, e.s.r., and n.m.r.) studies have been used to characterize the complexes. The i.r. spectra show that the thiosemicarbazones behave as bidentate ligands, either in the thione or thiolato form. Stereochemistries are proposed for the complexes on the basis of spectral and magnetic studies. Both the thiosemicarbazones and their complexes show either modest or no growth inhibitory activity against Aspergillus niger and Paecilomyces variotii.

DOI 10.11648/j.sjc.20140203.12
Published in Science Journal of Chemistry (Volume 2, Issue 3, June 2014)
Page(s) 17-26
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Synthesis, Thiosemicarbazones, Characterization, Complexes, Stereochemistries, Antifungal

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Author Information
  • Chemistry Department, College of Science and Humanity Studies, Salman bin Abdulaziz University, AlKharj, KSA.11942; Chemistry Department, Faculty of Science, Minoufiya University, Shebin El-Kom, Egypt

  • Chemistry Department, College of Education for Girls, Salman bin Abdulaziz University, KSA

  • Chemistry Department, College of Science and Humanity Studies, Salman bin Abdulaziz University, AlKharj, KSA.11942; Chemistry Department, Faculty of Science, Minoufiya University, Shebin El-Kom, Egypt

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    Ayman K. El-Sawaf, Amal Abdel Fatah Nassar, El-Sayed El-Samanody. (2014). Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones. Science Journal of Chemistry, 2(3), 17-26. https://doi.org/10.11648/j.sjc.20140203.12

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    ACS Style

    Ayman K. El-Sawaf; Amal Abdel Fatah Nassar; El-Sayed El-Samanody. Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones. Sci. J. Chem. 2014, 2(3), 17-26. doi: 10.11648/j.sjc.20140203.12

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    AMA Style

    Ayman K. El-Sawaf, Amal Abdel Fatah Nassar, El-Sayed El-Samanody. Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones. Sci J Chem. 2014;2(3):17-26. doi: 10.11648/j.sjc.20140203.12

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  • @article{10.11648/j.sjc.20140203.12,
      author = {Ayman K. El-Sawaf and Amal Abdel Fatah Nassar and El-Sayed El-Samanody},
      title = {Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones},
      journal = {Science Journal of Chemistry},
      volume = {2},
      number = {3},
      pages = {17-26},
      doi = {10.11648/j.sjc.20140203.12},
      url = {https://doi.org/10.11648/j.sjc.20140203.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.sjc.20140203.12},
      abstract = {The synthesis and characterization of copper(II) complexes with 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one thiosemicarbazone and N(4)-substituted thiosemicarbazones are reported. Elemental analysis, molar conductivities, magnetic measurements and spectral (i.r., electronic, e.s.r., and n.m.r.) studies have been used to characterize the complexes. The i.r. spectra show that the thiosemicarbazones behave as bidentate ligands, either in the thione or thiolato form. Stereochemistries are proposed for the complexes on the basis of spectral and magnetic studies. Both the thiosemicarbazones and their complexes show either modest or no growth inhibitory activity against Aspergillus niger and Paecilomyces variotii.},
     year = {2014}
    }
    

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    T1  - Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones
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    AU  - Amal Abdel Fatah Nassar
    AU  - El-Sayed El-Samanody
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    JF  - Science Journal of Chemistry
    JO  - Science Journal of Chemistry
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    EP  - 26
    PB  - Science Publishing Group
    SN  - 2330-099X
    UR  - https://doi.org/10.11648/j.sjc.20140203.12
    AB  - The synthesis and characterization of copper(II) complexes with 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one thiosemicarbazone and N(4)-substituted thiosemicarbazones are reported. Elemental analysis, molar conductivities, magnetic measurements and spectral (i.r., electronic, e.s.r., and n.m.r.) studies have been used to characterize the complexes. The i.r. spectra show that the thiosemicarbazones behave as bidentate ligands, either in the thione or thiolato form. Stereochemistries are proposed for the complexes on the basis of spectral and magnetic studies. Both the thiosemicarbazones and their complexes show either modest or no growth inhibitory activity against Aspergillus niger and Paecilomyces variotii.
    VL  - 2
    IS  - 3
    ER  - 

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