Contemporary Definitions of Hypoglycemia as Frequent and Dangerous Syndrome and Coma
American Journal of Life Sciences
Volume 7, Issue 5, October 2019, Pages: 83-90
Received: Sep. 27, 2019; Accepted: Oct. 17, 2019; Published: Oct. 29, 2019
Views 448      Downloads 154
Vyacheslav Semionovish Lukyanchikov, Medical Centre "Medstyle-Effect", Moscow, Russia
Article Tools
Follow on us
A decrease in blood glucose is a frequent and dangerous violation of the most important part of homeostasis - energy. The high frequency of hypoglycemia is explained by a pathogenetic relationship with many diseases and syndromes, as well as the important role of hypoglycemia as a physiological regulator of energy metabolism. The danger of hypoglycemia is that glucose is actually the only source of energy for nerve structures and a lack of glucose could lead to their damage. In addition, deep hypoglycemia and low glucose concentration in brain cells could lead to cerebral edema. Analyzes of the respectful literature for a 20-year period, as well as my own clinical experience, including the work as an endocrinologist surgeon. The article presents the definitions of hypoglycemia, the typology of the syndrome in terms of causes, development mechanisms and clinical forms, also issues of the clinic and laboratory diagnostics are defined. Algorithms for the treatment of hypoglycemic coma and pathogenetic diagnosis of the main variants of hypoglycemia are proposed. Hypoglycemic syndrome [HS] and hypoglycemic coma [HC] are frequent clinical and laboratory paroxysms, especially among patients with diabetes mellitus. These conditions are of great danger to the health and even to the lives of patients, and require quick, qualified help.
Hypoglycemia, Glycopenia, Hypoglycemic Coma, Urgent Endocrinopathies
To cite this article
Vyacheslav Semionovish Lukyanchikov, Contemporary Definitions of Hypoglycemia as Frequent and Dangerous Syndrome and Coma, American Journal of Life Sciences. Vol. 7, No. 5, 2019, pp. 83-90. doi: 10.11648/j.ajls.20190705.11
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Marks V., Rose F. Hypoglycemia. 2-nd ed. Blackwell Scientif. publ. N-Y: - 1981.
Lukyanchikov V. S., Endocrine Comas and Crises. M.: Academic Project. 2013. (in Rus.).
Shuvin Z., Felig F. Hypoglycemia. In: Endocrinology and Metabolism (transl. from English). Ed. F. Felig et al. M.: - Medicine. - 1985. - T. 2. - P. 218-258. (in Rus.).
Yager J., Young R. Non-hypoglycemia is an epidemic condition. // New Engl. J. Med. - 1974. - № 14. - Р. 507-508.
Inzucchi S., Kinder B. Endocrine Emergencies: Hypoglycemic and Hyperglycemic Crises. In: Textbook of Endocrine Surgery. (Eds. O. Ciark, Q-Y. Duh.). / WE Sounders Company. Washington etc.: - 1997. - Р. 175-181.
Boyle P. J. Hypoglycemia. In: Medical Management of Diabetes Mellitus (transl. from English). By J. Leaty etc. (Eds). Marcel Dekker Inc. NY, Basel. 2000. Ch. 31.
Ostroumova O. D., Akimova ES, Kochetkov A. I., Pereverzev A. P. Drug-induced hypoglycemia: a focus on drugs not belonging to the group of sugar-lowering drugs. // CONSILIUM Medicum. 2019. - T. 21. - No. 4. - P. 59-65. (in Rus.).
Foster D., Rubinstein A. Hypoglycemia, insulinoma and other hormone-active tumors of the pancreas. In the book: Internal Diseases (transl. from English). ed. E. Braunwald and others M.: - Medicine. - 1997. - T. 9. - P. 232-247. (in Rus.).
Kuzin N. M., Egorova L. V., Lakreeva MG. Gurevich L. E. Organic hyperinsulinism. // Clinical medicine. - 1998.- No. 4. - P. 7-11. (in Rus.).
Rostomyan L. G., Rozhinskaya L. Ya., Tyulpakov A. N. Clinical and genetic characteristics of the syndrome of multiple endocrine neoplasia type 1 and the principles of its treatment. // Farmtek. - 2010. - No. 3. - P. 50-56. (in Rus.).
Shustov S. B., Halimov U. Sh., Saluhov V. V., Trufanov G. E. Functional and Topical Diagnostic in Endocrinology. M.: GEOTAR Media. 2017. (in Rus.).
Zilber A. P. Sketches of Critical Medicine. M.: Med press Inform. 2006. (in Rus.).
Stefansson K., Arnason B. Neurological manifestations of systemic neoplasia. / In the book: Internal diseases. (translated from English). By E. Braunwald et al. (Eds.) M.: - Medicine. - 1996. - T. 8. - P. 123-131. (in Rus.).
Kamyshnikov V. S. Clinical laboratory tests from A to Z and their diagnostic profiles. / M.: - Medpress-Inform. - 2018. (in Rus.).
Koryachkin V. A. Formulas and Calculations in intensive Therapy. SPb.: GMU. 2000. (in Rus.).
Intensive Therapy. Contemporary Aspects. (transl. from English) By D. Sew, D. Wing (Eds.). M.: Medpress - Inform. 2008. (in Rus.).
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
Tel: (001)347-983-5186