Microgravity simulation in rats resulted to changes in eye lavage content. Molecular subfraction analysis with laser correlation spectroscopy revealed significant differences in the pattern of particle distribution in five intervals: 1.9 -2.56 nm, 4.64-6.25 nm, 91.3 nm, 165-300 nm, and 400-734 nm. Microgravity modeling induced a series of interrelated processes in the retina of experimental rats manifesting in decreasing of total and layer-by-layer thickness of the retina, mild edema, and consequently, the increasing of specific density of neurons. In the inner nuclear layer, the cell density decreased because of the amacrine and bipolar cells. These changes could be explained by relative ischemia of the retinal layers, which are dependent on the retinal vessels circulation system.
| DOI | 10.11648/j.ajls.s.2015030102.14 |
| Published in |
American Journal of Life Sciences (Volume 3, Issue 1-2, January 2015)
This article belongs to the Special Issue Space Flight Factors: From Cell to Body |
| Page(s) | 18-24 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Amacrine Cells, Bipolar Cells, Laser Correlation Spectroscopy, Microgravity Simulation, Muller Cells, Retinal Vessels
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APA Style
Margarita Vyalkina, Anatoly Fedorov, Erika Eskina, Yulia Medvedeva, Elena Arkhipova, et al. (2014). Metabolic and Morphological Changes in Rats’ Eye after 7-Days Microgravity Simulation. American Journal of Life Sciences, 3(1-2), 18-24. https://doi.org/10.11648/j.ajls.s.2015030102.14
ACS Style
Margarita Vyalkina; Anatoly Fedorov; Erika Eskina; Yulia Medvedeva; Elena Arkhipova, et al. Metabolic and Morphological Changes in Rats’ Eye after 7-Days Microgravity Simulation. Am. J. Life Sci. 2014, 3(1-2), 18-24. doi: 10.11648/j.ajls.s.2015030102.14
AMA Style
Margarita Vyalkina, Anatoly Fedorov, Erika Eskina, Yulia Medvedeva, Elena Arkhipova, et al. Metabolic and Morphological Changes in Rats’ Eye after 7-Days Microgravity Simulation. Am J Life Sci. 2014;3(1-2):18-24. doi: 10.11648/j.ajls.s.2015030102.14
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Download@article{10.11648/j.ajls.s.2015030102.14,
author = {Margarita Vyalkina and Anatoly Fedorov and Erika Eskina and Yulia Medvedeva and Elena Arkhipova and Marina Lebedeva and Nadezhda Khlebnikova and Mikhail Baranov and Mikhail Karganov},
title = {Metabolic and Morphological Changes in Rats’ Eye after 7-Days Microgravity Simulation},
journal = {American Journal of Life Sciences},
volume = {3},
number = {1-2},
pages = {18-24},
doi = {10.11648/j.ajls.s.2015030102.14},
url = {https://doi.org/10.11648/j.ajls.s.2015030102.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.s.2015030102.14},
abstract = {Microgravity simulation in rats resulted to changes in eye lavage content. Molecular subfraction analysis with laser correlation spectroscopy revealed significant differences in the pattern of particle distribution in five intervals: 1.9 -2.56 nm, 4.64-6.25 nm, 91.3 nm, 165-300 nm, and 400-734 nm. Microgravity modeling induced a series of interrelated processes in the retina of experimental rats manifesting in decreasing of total and layer-by-layer thickness of the retina, mild edema, and consequently, the increasing of specific density of neurons. In the inner nuclear layer, the cell density decreased because of the amacrine and bipolar cells. These changes could be explained by relative ischemia of the retinal layers, which are dependent on the retinal vessels circulation system.},
year = {2014}
}
TY - JOUR T1 - Metabolic and Morphological Changes in Rats’ Eye after 7-Days Microgravity Simulation AU - Margarita Vyalkina AU - Anatoly Fedorov AU - Erika Eskina AU - Yulia Medvedeva AU - Elena Arkhipova AU - Marina Lebedeva AU - Nadezhda Khlebnikova AU - Mikhail Baranov AU - Mikhail Karganov Y1 - 2014/12/27 PY - 2014 N1 - https://doi.org/10.11648/j.ajls.s.2015030102.14 DO - 10.11648/j.ajls.s.2015030102.14 T2 - American Journal of Life Sciences JF - American Journal of Life Sciences JO - American Journal of Life Sciences SP - 18 EP - 24 PB - Science Publishing Group SN - 2328-5737 UR - https://doi.org/10.11648/j.ajls.s.2015030102.14 AB - Microgravity simulation in rats resulted to changes in eye lavage content. Molecular subfraction analysis with laser correlation spectroscopy revealed significant differences in the pattern of particle distribution in five intervals: 1.9 -2.56 nm, 4.64-6.25 nm, 91.3 nm, 165-300 nm, and 400-734 nm. Microgravity modeling induced a series of interrelated processes in the retina of experimental rats manifesting in decreasing of total and layer-by-layer thickness of the retina, mild edema, and consequently, the increasing of specific density of neurons. In the inner nuclear layer, the cell density decreased because of the amacrine and bipolar cells. These changes could be explained by relative ischemia of the retinal layers, which are dependent on the retinal vessels circulation system. VL - 3 IS - 1-2 ER -
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