Antioxidant Potential and Phytochemical Screening of Aristolochiabraceelata: An in vitro Approach
American Journal of Life Sciences
Volume 4, Issue 5, October 2016, Pages: 113-117
Received: Dec. 14, 2015;
Accepted: Dec. 31, 2015;
Published: Oct. 19, 2016
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Fayyad Alzain, Chemistry Department, Omdurman Islamic University, Khartoum, Sudan
Mohamed Nasraldeen, Medical Biochemistry Research Department, Medicinal and Aromatic Plants Research Institute, National Centerfor Research, Khartoum, Sudan
Sufyan Awadalkareem, Chemistry Department, Omdurman Islamic University, Khartoum, Sudan; Medical Biochemistry Research Department, Medicinal and Aromatic Plants Research Institute, National Centerfor Research, Khartoum, Sudan
Alsiddig Osama, Chemistry Department, Omdurman Islamic University, Khartoum, Sudan
Mohamed Ezeldin, Chemistry Department, Omdurman Islamic University, Khartoum, Sudan
Omer M. Eltayeb, Medical Biochemistry Research Department, Medicinal and Aromatic Plants Research Institute, National Centerfor Research, Khartoum, Sudan
Ahmed Ibrahim, Chemistry Department, Omdurman Islamic University, Khartoum, Sudan
Alshareef Algasim, Chemistry Department, Omdurman Islamic University, Khartoum, Sudan
Hashim Saeed, Chemistry Department, Omdurman Islamic University, Khartoum, Sudan
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The present study was designed to investigate the antioxidant activity of Aristolochiabraceelata whole plant and fruit. Phytochemical study was piloted to detect the bioactive compounds, which have been responsible for the biological activities. The antioxidant activities were conducted via DPPH radical scavenging assay. Potential antioxidant activity was presented by ethanol crude extract was motivated to evaluate the fractions of n-hexane chloroform, ethyl acetate, n-butanol and water, the radical scavenging activities of whole plant were found to be 84 ± 0.02, 82.5 ± 0.04, 78.2 ± 0.04, 92.9 ± 0.03, 88.9 ± 0.02, 77.3± 0.05 respectively, while the fruit extracts displayed a higher potentials in crude and lower with fractions. The results of phytochemical screening showed the presence ofFlavonoids, Saponins, Alkaloid, Tannins, Phenols, Triterpene, Phytosterol, Anthraquinones and Carbohydrates. This study give rise to antioxidant property of studied plant, and showed interesting correlation with the phytochemical constituents and biological activities.
Aristolochiabraceelata, Antioxidant, Phytochemical Screening, Radical Scavenging
To cite this article
Omer M. Eltayeb,
Antioxidant Potential and Phytochemical Screening of Aristolochiabraceelata: An in vitro Approach, American Journal of Life Sciences.
Vol. 4, No. 5,
2016, pp. 113-117.
Copyright © 2016 Authors retain the copyright of this article.
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Aiyelaagbe O, Osamudiamen PM. Phytochemical Screening for Active Compounds in Mangiferaindica Leaves from Ibadan, Oyo State, Plant Sciences Research 2009; 1(2):11-13.
Awosika F. Local Medicinal plants and health of consumers.Clin.Pharm.Herbal Med. 1991; 9:28-29.
Balandrin MF, Klocke JA, WurteleES, Bollinger WH. Natural plant chemicals: sources of industrial and medicinal materials, Science 1985; 228:1154.
CassadyJM, Douros JD. Anticancer Agents Based on Natural Product Models, Academic Press, New York, 1980.
Denwick PM. Natural Products A Biosynthetic Approach. 2nd Edn., John Wiley and Sons, Ltd., England, 2002; 241-243.
Dharmananda S. Gallnuts and the uses of tannins in Chinese medicine. A paper Delivered at the Institute for Traditional Medicine, Portland, Oregon, 2003.
Finar IL. Chemistry; Stereochemistry and the Chemistry of Natural products, 5th Edn, Longman Group, UK., 1989; 2:517-605.
Gareth Thomas.Medicinal Chemistry.2nd edition.John Wiley & Sons Ltd, 2007.
Harborne J. phytochemical methods.2nd edition.Chapman and Hall, 1984.
Harborne JB. Introduction to Ecological Biochemistry, 2nd ed., Academic Press, New York, 1982.
Heslem E. Plant Polyphenol: Vegetal Tannin Telisted- Chemistry and Pharmacology of Natural Products, 1stEdn., Cambridge University Press, Cambridge, Massachusetts, 1989, 169.
Kamel JM. An extract of the mesocarps of fruits of Balaniteaegyptiaca exhibited a prominent anti-diabetic properties in Mice. Chem. Pharmacol. Bull 1991; 39:1229-1233.
Mann J, Davidson RS, Hobbs JB, Banthorpe DV, HarborneJB.NaturalProducts.Their Chemistry and Biological Significance, Addison Wesley Longman, Harlow, UK, 1994. 14. Mark Percival. Antioxidants.Clinical Nutrition Insights 1998; 31:01-04.
Mariani E., PolidoriMC., Cherubini A., Mecocci P. Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview. J Chromatogr B AnalytTechnol Biomed Life Sci, 2005; 827(1):65–75.
Odebiyi O, Sofowora EA. Phytochemical screening of Nigerian medicinal plants.L.Coydia 1978; 41:41-234.
Ogunleye DS, Ibitoye SF. Studies of antimicrobial activity and chemical constituents of XimeniaAmericana.Trop.J Pharm Res. 2003; 2:239-241.
Prerna U., Vikas S. Therapy of Alzheimer’s disease: An update.African Journal of Pharmacy and Pharmacology. 2010; 4, 6, 408-421.
Rauha JP, Remes S, Herinonen W, Hopia M, Kgjala T, Pitinlaja K et al. Antimicrobial effects of finished plant extract containing flavanoids and other phenolic compounds. Int. J Food Microbiol.2000; 56:3-12.
Rosenthal GA, Janzen DH. (Eds.), Herbivores: Their Interaction with Secondary Plant Metabolites, Academic Press, New York, 1979.
Shimada K., Fujikawa K., Yahara K., Nakamura T. antioxidative properties of xanthan on the antioxidation of soybean oil in cyclodextrin emulsion. Journal of Agric food chemistry, 1992; 40:945-948.
Sies H. Oxidative stress: oxidants and antioxidants. Exp. Physiol, 1997; 82(2): 291–295.
Tiwari P, Kumar B, Kaur M, Kaur G, Kaur H. Phytochemical screening and Extraction: A Review. InternationalePharmaceuticaSciencia 2011; 1:98-106.
TreaseG.E., Evans W.C. Pharmacognosy. Alden Press, Oxford, 1996; 213-232.
Trease GE, Evans MD. A text book ofPharmacognosy, 13th Edn.Baillier, Tindal and Caussel, London.1989, 144-148.
Trease GE, Evans WC. Textbook of Pharmacognosy, 12thEdn.Balliere, Tindall, London, 1983.
Tyler VE, Brady LR, Robbers JE. Pharmacognosy, Lea &Febiger, Philadelphia, 1981, 8.
Tyler VE, Brady LR, Roberts JE. Pharmacology.Lea and Ferbiger, Philadelphia. 1988, 85-90.