Prevalence of MRSA and Its Antibiotic Susceptibility Pattern in Ujjain, MP.
European Journal of Biophysics
Volume 1, Issue 5, October 2013, Pages: 37-40
Received: Dec. 15, 2013;
Published: Jan. 30, 2014
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L. Suresh Babu, Dept. of Microbiology, RD Gardi Medical College, Surasa, Ujjain, MP, India
Background and objectives: MRSA is known to cause community and hospital acquired infections due to its multiple drug resistance. The objectives of this study were to elucidate the prevalence of MRSA among clinical cases of both community and hospital acquired infections and to evaluate the invitro susceptibility pattern of different antibiotics against isolated MRSA strains. Methods: Clinical samples were collected from both inpatients and outpatients including swabs from operation theatres and ICUs and were subjected to MRSA screening by the conventional methods. Thus isolated MRSA were subjected to antibiotic susceptibility. Results & interpretation: A total of 145 strains of Staphylococcus aureus were isolated. Among these 115 were from indoor patients, 21 from outdoor and 9 were of environmental sources. MRSA was 46% out of the total isolations and MSSA was 54%. The maximum isolation of MRSA was from inpatients (49.5%). The highest isolation rate of 92% of MRSA was reported from blood samples. Vancomycin was the most effective of all drugs used against MRSA strains in invitro susceptibility pattern. On the other hand moxifloxacin and gatifloxacin were the most effective against MSSA strains. Conclusions: MRSA is very much prevalent in this part of the country. A dip in the susceptibility of MRSA to vancomycin, prompts an immediate evolving of an alternate drug.
L. Suresh Babu,
Prevalence of MRSA and Its Antibiotic Susceptibility Pattern in Ujjain, MP., European Journal of Biophysics.
Vol. 1, No. 5,
2013, pp. 37-40.
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