Phyllanthus emblica Linn. (Amla) - A Natural Gift to Humans: An Overview
Fairuz Fatema Priya,
Mohammad Sayful Islam
Issue:
Volume 5, Issue 1, February 2019
Pages:
1-9
Received:
16 August 2018
Accepted:
18 October 2018
Published:
15 February 2019
Abstract: Medicinal plants are the precious gift of nature which plays vital role in healthcare system of developing nation and potent source of medicament to heal various diseases in the world. It plays a vital role to preserve our health. Medicinal plants are believed to be much safer. These days, the use of herbal products has become the foremost option for human all over the world because of curing treatment without any side effect. Ayurveda, the oldest health system in the world, provokes the uses amla to treat a host of diseases and promote positive health. It is a well-known fact that all parts of amla are useful in the treatment of various diseases. Among all, the most important part is fruit. Amla fruit is the richest source of vitamin C. Chemical composition of the amla fruit contains more than 80% of water. It also contains protein, carbohydrates, fiber, amino acids and minerals such as calcium, phosphorus, iron, niacin, carotene, thiamine, riboflavin etc. The chemical constituents present in the plant include tannins, gallic acid, ellagic acid, emblicol, phyllembin, lupeol, essential oil, fixed oil etc. Amla fruit is widely used as diuretic, laxative, liver tonic, antipyretic, hair tonic, ulcer preventive and for common cold, fever as alone or in combination with other plants. Research reports on amla reveals its analgesic, anti-tussive, cardioprotective, cytoprotective, immunomodulatory, chemopreventive, antioxidant, memory enhancing, anticancer, antidiabetic and some others properties. In this article, we review the morphology, distribution, nutritional value, chemical constituents, medicinal uses of amla.
Abstract: Medicinal plants are the precious gift of nature which plays vital role in healthcare system of developing nation and potent source of medicament to heal various diseases in the world. It plays a vital role to preserve our health. Medicinal plants are believed to be much safer. These days, the use of herbal products has become the foremost option f...
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Phenethyl Isothiocyanate Inhibits Nasopharyngeal Carcinoma Cell Growth and Invasion
Chenggang Mao,
Xiaochun Zhou,
Yidao Jiang,
Lijia Wan,
Zezhang Tao
Issue:
Volume 5, Issue 1, February 2019
Pages:
10-16
Received:
4 January 2019
Accepted:
23 January 2019
Published:
15 February 2019
Abstract: The dietary compound phenethyl isothiocyanate (PEITC), is an active component of cruciferous vegetables and markedly inhibits the growth of a variety of tumors. However, its role in human nasopharyngeal carcinoma (NPC) is obscure. The aim of the present study was to elucidate the possible mechanisms whereby PEITC exhibited anticancer properties in human nasopharyngeal carcinoma NPC-TW01 cells in vitro. The experiment results exhibited that in a dose- and time-dependent manner treatment of NPC-TW01 cells with PEITC significantly inhibited cell proliferation, promoted apoptosis with concurrent G2/M cell cycle arrest and inhibited cell invasion in a dose-dependent manner. These effects were accompanied by significant alterations in the expression levels of key proteins associated with pro-survival signaling pathways, including PI3K, Akt, ERK, NF-κB, Bcl, Bax, cyclin B, CDK4 and CDK6. Significantly, these effects were not reflected in 16HBE normal human bronchial epithelial cells, indicating a safe range of treatment concentrations between 0 and 10 μM PEITC. In conclusion, PEITC exhibited significant anticancer effects against human nasopharyngeal carcinoma cells in vitro with low toxicological impact on normal bronchial epithelial cells. This was achieved through dysregulation of key proteins involved in the occurrence and development of tumors, and this approach may be applied to the clinical treatment of NPC and in drug screening.
Abstract: The dietary compound phenethyl isothiocyanate (PEITC), is an active component of cruciferous vegetables and markedly inhibits the growth of a variety of tumors. However, its role in human nasopharyngeal carcinoma (NPC) is obscure. The aim of the present study was to elucidate the possible mechanisms whereby PEITC exhibited anticancer properties in ...
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Phytochemical Analysis of Telfaria Occidentals and Ocimum Gratissimum Samples Collected from Gwarimpa Abuja Nigeria
Abdulrasheed Hadiza Haruna,
Mohammed Mairo,
Mariya Akilu
Issue:
Volume 5, Issue 1, February 2019
Pages:
17-21
Received:
22 January 2019
Accepted:
5 March 2019
Published:
21 March 2019
Abstract: This study aims at determining the presence of phytochemical constituents in Telfaria occidentalis and Ocimum gratissimum collected from a location in Abuja, FCT. Standard laboratory procedures were employed to achieve the set objectives. To ascertain the phytochemical components responsible for the ethno medicinal properties, a qualitative and quantitative screening of the extracts of the sampled plants was conducted. Telfaria occidentalis and Ocimum gratissimum leaves were collected from the Kado-Bimko market, Gwarinpa-Abuja in October 2016. Phytochemical screening of the plant materials revealed some differences in the phytochemical constituents of the plants tested but showed the presence of Flavonoids, Alkaloids, Anthraquinones, Saponins, and Tannins. The present data suggest that these extracts could be potential sources phytochemicals that could be of great importance for the treatment of various diseases. It is expected that the important phytochemicals recognised in the study of the medicinal plant sample extracts will be very useful in the curing of various diseases in Nigeria.
Abstract: This study aims at determining the presence of phytochemical constituents in Telfaria occidentalis and Ocimum gratissimum collected from a location in Abuja, FCT. Standard laboratory procedures were employed to achieve the set objectives. To ascertain the phytochemical components responsible for the ethno medicinal properties, a qualitative and qua...
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