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Prevalence of Drug Eluting Stent Restenosis and Its Correlation with Culprit Coronary Artery
Anthony Matta,
Joseph Bou Assi,
Alexandre Kharma,
Nicolas Moussallem
Issue:
Volume 2, Issue 4, December 2018
Pages:
75-78
Received:
20 August 2018
Accepted:
18 September 2018
Published:
29 November 2018
DOI:
10.11648/j.ccr.20180204.11
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Abstract: In-Stent Restenosis (ISR) remains a significant problem for the treatment of coronary artery disease (CAD). Our study was conducted to evaluate the prevalence of significant restenosis of drug eluting stent (DES), as to its correlation with the culprit coronary artery. A retrospective study was conducted on 924 consecutive patients undergoing percutaneous coronary intervention (PCI) for DES implantation and who were followed-up by cardiac coronarography within 1 year. Cardiac coronarography films were reviewed for the presence or the absence of significant ISR, and for detection of the underlying culprit coronary artery. 2x2 tables and Chi square test were used. P value<0.05 was considered significant. The revision of cardiac coronarography films of follow-up for 924 included angioplasties showed significant ISR in 165 DES out of the 1494 implanted ones. Statistical analysis estimates the prevalence of DES restenosis at 11%. Taking into consideration the different coronary arteries, it is respectively: 8.79% in Left Anterior Descending (LAD) where ISR was found in 63 stents out of the 654 inserted ones, 11.38% in circumflex (Cx) where ISR was found in 42 stents out of the 327 inserted ones, and 14.7% in right coronary artery (RCA) where ISR was found in 60 stents out of the 342 implanted ones. A negative significant relationship was detected between the prevalence of ISR and LAD coronary artery lesion in opposition to a positive significant relationship between the prevalence of ISR and RCA lesion. The prevalence of significant ISR of DES is 11% and it is significantly higher in stents implanted in RCA as compared to stents implanted in Cx and LAD with statistical evidence of significant correlation between the prevalence of ISR and the involved culprit coronary artery.
Abstract: In-Stent Restenosis (ISR) remains a significant problem for the treatment of coronary artery disease (CAD). Our study was conducted to evaluate the prevalence of significant restenosis of drug eluting stent (DES), as to its correlation with the culprit coronary artery. A retrospective study was conducted on 924 consecutive patients undergoing percu...
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Effect of Health Education and Follow-up on the Control of Residual Cardiovascular Risk in Patients Undergoing PCI
Yu Jian,
Liu Lihong,
Chen Jiali,
Huang Xianzhen,
Qiu Weiyu,
Wang Jinlong
Issue:
Volume 2, Issue 4, December 2018
Pages:
79-82
Received:
3 October 2018
Accepted:
10 November 2018
Published:
19 December 2018
DOI:
10.11648/j.ccr.20180204.12
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Abstract: Objective To analyze the effect of health education and follow-up on the control of residual cardiovascular risk in patients after percutaneous transluminal coronary intervention (PCI). Methods One hundred participants admitted to the Department of Cardiology of The First Affiliated Hospital of Jinan University from October 2015 to October 2016 were randomly divided into control group and research group after undergoing PCI. Two groups received the same level of health education when discharged. The research group went back to the hospital to receive health education and health guidance every 3 months while the control group did not return to receive lecture and training but only returned to the outpatient clinic for regular or irregular reexamination and medication, and received telephone follow-up. The two-year follow-up of the two groups was summarized and analyzed. Results The cardiovascular event rate, rehospitalization rate caused by cardiovascular disease and the incidence of second stent implantation in the research group were significantly lower than those in the control group while the standard-reaching rate of low density lipoprotein and the drug compliance were significantly higher than those in the control group, and there was significant difference between the two groups (P < 0.05). Before the implementation of health education, there was no significant difference in the health knowledge score between the two groups (t=-0.211, P>0.005), but after the implementation of health education, the score of the research group was (25.96 + 0.44) which was significantly higher than that of the control group (P < 0.05). Conclusion Health education and follow-up have great effect on the control of residual cardiovascular risk in patients after PCI, which helps to develop a healthy life style, effectively reduce the incidence of risk events, and improve the prognosis of patients.
Abstract: Objective To analyze the effect of health education and follow-up on the control of residual cardiovascular risk in patients after percutaneous transluminal coronary intervention (PCI). Methods One hundred participants admitted to the Department of Cardiology of The First Affiliated Hospital of Jinan University from October 2015 to October 2016 wer...
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Low-Dose Dabigatran May Be Safely Used as an Alternative to Warfarin for Peri-Procedural Anticoagulation During Atrial Fibrillation Ablation
Haixia Xu,
Yanmin Zhu,
Ying Hua,
Yinhao Huang,
Qi Lu
Issue:
Volume 2, Issue 4, December 2018
Pages:
83-90
Received:
6 October 2018
Accepted:
24 October 2018
Published:
19 December 2018
DOI:
10.11648/j.ccr.20180204.13
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Abstract: Peri-procedural anticoagulation for atrial fibrillation (AF) ablation must be optimized to reduce the occurrence of bleeding and thromboembolic complications. In this study, the safety of two anticoagulants were compared between the commonly used warfarin and a potential alternative, orally administered low-dose (110 mg bid) dabigatran. A total of 117 Han Chinese patients undergoing AF ablation were included in the study. In all, 67 patients were administered dabigatran (110 mg) twice daily, while the other 50 received a therapeutically effective dose of warfarin. Thromboembolic and bleeding complications were compared between the two groups. No significant baseline differences were found between the groups. Only one thromboembolic complication (2.0%) occurred in the warfarin group, while no complications occurred in the dabigatran group (p = 0.43). Compared to the warfarin group, the dabigatran group showed a similar rate of major bleeding events (2.0% vs. 0; p = 0.43), but a significantly lower rate of minor bleeding events (9.0% vs. 22%; p = 0.048), total bleeding events (9% vs. 24%; p = 0.03), and bleeding and thromboembolic complications taken together (9% vs. 26%; p = 0.01). In Conclusion, the incidence of minor bleeding events after AF ablation was lower in those administered low-dose dabigatran (110 mg bid) than in those administered warfarin, while the risks of thromboembolic and major bleeding complications were similar between the two groups. This result indicates that low-dose dabigatran would be safer than warfarin in Chinese patients undergoing AF ablation.
Abstract: Peri-procedural anticoagulation for atrial fibrillation (AF) ablation must be optimized to reduce the occurrence of bleeding and thromboembolic complications. In this study, the safety of two anticoagulants were compared between the commonly used warfarin and a potential alternative, orally administered low-dose (110 mg bid) dabigatran. A total of ...
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Bicameral Pacemaker Implant in an Extremely Rare Case of Left Superior Vena Cava Anatomic Variant
Lorena Harbuz,
Camelia Georgescu,
Octavian Zara,
Sergiu Sipos,
Radu Ciudin
Issue:
Volume 2, Issue 4, December 2018
Pages:
91-97
Received:
22 October 2018
Accepted:
15 November 2018
Published:
19 December 2018
DOI:
10.11648/j.ccr.20180204.14
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Abstract: The most common congenital venous anomaly of the thoracic systemic venous return is the persistence of the left superior vena cava (PLSVC), occurring in 0.3% to 0.5% of individuals in the general population, and in 12% of individuals with other congenital heart abnormalities. 50% of the patients with isolated PLSVC have other cardiac malformations (atrial septal defect, endocardial cushion or tetralogy of Fallot). The basis for persistence of the left superior vena cava (LSVC), usually associated with other cardiac malformations, is poorly understood. The presence of a PLSVC has a significant influence of the anatomy of the heart and venous system. There is very little in the literature that specifically addresses the potential importance of the incidental finding of PLSVC to surgeons, interventional radiologists, and other physicians actively involved in central venous access device placement. The current review is a case report of persistent left superior vena cava associated with severe disorders of intra-cardiac conduction leading to specific symptoms. This venous malformation was identifies incidentally in a 80 years old patient during the procedure of pacemaker implantation. The venography showed isolated PLSVC with a bridging vein that drained the right jugular and right subclavian vein and joined the left brachiocephalic vein to form the PLSVC, which descendent on the left side of the mediastinum and drained into the right atrium via a dilated coronary sinus.
Abstract: The most common congenital venous anomaly of the thoracic systemic venous return is the persistence of the left superior vena cava (PLSVC), occurring in 0.3% to 0.5% of individuals in the general population, and in 12% of individuals with other congenital heart abnormalities. 50% of the patients with isolated PLSVC have other cardiac malformations ...
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Relation Between Serum Ferritin Level and the Left Ventricular Mass Index (LVMI) in Maintenance Hemodialysis Patients
Ahmed Eldeeb,
Ahmed Hosny El-Adawy,
Elshahat Yousef,
Ahmed Ibrahim,
Mostafa Anis Mahmoud,
Hany Abdel Shakour,
Mohamed Omran
Issue:
Volume 2, Issue 4, December 2018
Pages:
98-103
Received:
5 November 2018
Accepted:
16 November 2018
Published:
19 December 2018
DOI:
10.11648/j.ccr.20180204.15
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Abstract: Among hemodialysis (HD) patients, the left ventricular hypertrophy (LVH) is a common cardiovascular morbidity predictor. Ferritin level was considered as a clinical marker of iron storage and associated with cardiovascular mortality in chronic kidney disease (CKD) patients. The relationship between ferritin level and cardiac function in maintenance hemodialysis patients has not yet fully investigated. This study aimed to investigate the relationship between serum ferritin level and left ventricular mass index (LVMi) in hemodialysis patients. In this study, 70 regular chronic hemodialysis patients were included in a cross-sectional study (43 men and 27 women). The patients were sub-grouped into two groups according to the ferritin levels (patients with serum ferritin <800ng/ml (n=40), and patients with serum ferritin ≥800ng/ml (n=30)). Left ventricular mass (LVM), Left ventricular mass index (LVMi) and Left ventricular mass/hight 2.7 (LVM/Ht2.7) were evaluated by echocardiography. The patients with serum ferritin level ≥800 ng/ml showed significantly higher LVM, LVMI and LVM/Ht2.7 than other group. LVM, LVMI and LVM/Ht2.7 were significantly correlated to ferritin and hs-CRP. Regarding to the linear regression analysis, serum ferritin level was founded to be an independent predictors of LVM/Ht2.7 and but not for LVM nor LVMi. While, Highly sensitive C-reactive protein (hs-CRP) was founded to be independent predictors of LVM, LVMi and LVM/Ht2.7. This study showed that LVM, LVMI and LVM/ Ht2.7 are significantly elevated in patients with serum ferritin level ≥800 ng/ml. The serum ferritin was found to be independent predictors of LVH (represented by LVM/ Ht2.7) in maintenance HD patients.
Abstract: Among hemodialysis (HD) patients, the left ventricular hypertrophy (LVH) is a common cardiovascular morbidity predictor. Ferritin level was considered as a clinical marker of iron storage and associated with cardiovascular mortality in chronic kidney disease (CKD) patients. The relationship between ferritin level and cardiac function in maintenance...
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