Advances in Biochemistry

Volume 2, Issue 2, April 2014

  • Elevated Level of Interleukin-29: A Proinflammatory Role in Synovial Inflammation of Rheumatoid Arthritis

    Dalia A. Shaheen, Hisham M. Habib

    Issue: Volume 2, Issue 2, April 2014
    Pages: 29-33
    Received: 13 March 2014
    Accepted: 09 April 2014
    Published: 20 April 2014
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    Abstract: Background: The multiple pro-inflammatory cascades described in RA lead to persistent synovitis, resulting in articular cartilage and bone damages. The up-regulation of interferon-inducible genes has been found in the synovial lining regions and may play an important role in the pathogenesis of RA. Objective: The aim of the current study is to exam... Show More
  • The Effect of Serum Free Testosterone Level on Glycemic Control and Atherosclerosis in Type 2 Diabetic Men

    Dalia A. Shaheen, Doaa A. Shahin, Alaa Aldeen Habib, Amani M. El Amin Ali

    Issue: Volume 2, Issue 2, April 2014
    Pages: 34-39
    Received: 10 May 2014
    Accepted: 29 May 2014
    Published: 10 June 2014
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    Abstract: Background: Atherosclerosis is a complex disease of the arteries characterized by endothelial dysfunction, vascular inflammation, and the build-up of lipids within the intima of the vessel wall. Testosterone has a central or permissive role in pathogenesis of the metabolic syndrome and type 2 diabetes. Insulin resistance is associated with several ... Show More