Background: Evaluating Foveal avascular zone by OCTA (Optical Coherence Tomography angiography) in diabetic patients, has a crucial role in early detection of pathophhsiological changes affecting the macular area, and has a pedective value for early retinal neuro degenerative changes. Materials and experiments: Aim: To evaluate dimensions of Foveal Avascular Zone (FAZ) at level of superficial and deep capillary plexuses (SCP/DCP) in patients with different grades of non proliferative diabetic retinopathy without Diabetic Macular Edema (DME) using OCTA. Eighty type II diabetes mellitus patients and 20 healthy control, ecxluding proliferative diabetic retinopathy and DME. Divided to four groups according to ETDRS Classification. All undewent: measurement of glycosylated hemoglobin level, standard Structural OCT for the macula and optic nerve head with OCTA for evaluation of FAZ in both SCP and DCP networks of all eyes using (Heidelberg engineering, OCT spectralis, Germany) (SD-OCT). Results: Mean FAZ in SCP in control group (0.32 ± 0.12) mm2 versus (0.44 ± 0.17) mm2 in patients` group, while FAZ IN DCP (0.23) mm2 ± 0.12 in controls versus (0.34 ± 0.16) mm2 in patients. There was a statistically significant wider FAZ in DR patients (P-value 0.003). Conclusion: Enlargement of FAZ in SCP and DCP in patients with moderate to severe NPDR without DME was detected using OCTA, Preceeded by reduction in thickness of ORL and GCC layer. This can be used to monitor the progression of the disease and to evaluate the response to treatment.
| Published in | International Journal of Ophthalmology & Visual Science (Volume 7, Issue 1) |
| DOI | 10.11648/j.ijovs.20220701.12 |
| Page(s) | 6-13 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Diabetic Retinopathy, Foveal Avascular Zone, Optical Coherence Tomography Angiography
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APA Style
Mohamed M. Halfawy, Abelrahman Gaber Salman, Azza M. A. Said, Tarek El Beltagi, Marwa A. Karim. (2022). Comprehensive Foveal Avascular Zone and Retinal Evaluation with Their Correlation to Visual Acuity and Glycemic Control in Diabetics Without Macular Edema. International Journal of Ophthalmology & Visual Science, 7(1), 6-13. https://doi.org/10.11648/j.ijovs.20220701.12
ACS Style
Mohamed M. Halfawy; Abelrahman Gaber Salman; Azza M. A. Said; Tarek El Beltagi; Marwa A. Karim. Comprehensive Foveal Avascular Zone and Retinal Evaluation with Their Correlation to Visual Acuity and Glycemic Control in Diabetics Without Macular Edema. Int. J. Ophthalmol. Vis. Sci. 2022, 7(1), 6-13. doi: 10.11648/j.ijovs.20220701.12
AMA Style
Mohamed M. Halfawy, Abelrahman Gaber Salman, Azza M. A. Said, Tarek El Beltagi, Marwa A. Karim. Comprehensive Foveal Avascular Zone and Retinal Evaluation with Their Correlation to Visual Acuity and Glycemic Control in Diabetics Without Macular Edema. Int J Ophthalmol Vis Sci. 2022;7(1):6-13. doi: 10.11648/j.ijovs.20220701.12
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Download@article{10.11648/j.ijovs.20220701.12,
author = {Mohamed M. Halfawy and Abelrahman Gaber Salman and Azza M. A. Said and Tarek El Beltagi and Marwa A. Karim},
title = {Comprehensive Foveal Avascular Zone and Retinal Evaluation with Their Correlation to Visual Acuity and Glycemic Control in Diabetics Without Macular Edema},
journal = {International Journal of Ophthalmology & Visual Science},
volume = {7},
number = {1},
pages = {6-13},
doi = {10.11648/j.ijovs.20220701.12},
url = {https://doi.org/10.11648/j.ijovs.20220701.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20220701.12},
abstract = {Background: Evaluating Foveal avascular zone by OCTA (Optical Coherence Tomography angiography) in diabetic patients, has a crucial role in early detection of pathophhsiological changes affecting the macular area, and has a pedective value for early retinal neuro degenerative changes. Materials and experiments: Aim: To evaluate dimensions of Foveal Avascular Zone (FAZ) at level of superficial and deep capillary plexuses (SCP/DCP) in patients with different grades of non proliferative diabetic retinopathy without Diabetic Macular Edema (DME) using OCTA. Eighty type II diabetes mellitus patients and 20 healthy control, ecxluding proliferative diabetic retinopathy and DME. Divided to four groups according to ETDRS Classification. All undewent: measurement of glycosylated hemoglobin level, standard Structural OCT for the macula and optic nerve head with OCTA for evaluation of FAZ in both SCP and DCP networks of all eyes using (Heidelberg engineering, OCT spectralis, Germany) (SD-OCT). Results: Mean FAZ in SCP in control group (0.32 ± 0.12) mm2 versus (0.44 ± 0.17) mm2 in patients` group, while FAZ IN DCP (0.23) mm2 ± 0.12 in controls versus (0.34 ± 0.16) mm2 in patients. There was a statistically significant wider FAZ in DR patients (P-value 0.003). Conclusion: Enlargement of FAZ in SCP and DCP in patients with moderate to severe NPDR without DME was detected using OCTA, Preceeded by reduction in thickness of ORL and GCC layer. This can be used to monitor the progression of the disease and to evaluate the response to treatment.},
year = {2022}
}
TY - JOUR T1 - Comprehensive Foveal Avascular Zone and Retinal Evaluation with Their Correlation to Visual Acuity and Glycemic Control in Diabetics Without Macular Edema AU - Mohamed M. Halfawy AU - Abelrahman Gaber Salman AU - Azza M. A. Said AU - Tarek El Beltagi AU - Marwa A. Karim Y1 - 2022/01/25 PY - 2022 N1 - https://doi.org/10.11648/j.ijovs.20220701.12 DO - 10.11648/j.ijovs.20220701.12 T2 - International Journal of Ophthalmology & Visual Science JF - International Journal of Ophthalmology & Visual Science JO - International Journal of Ophthalmology & Visual Science SP - 6 EP - 13 PB - Science Publishing Group SN - 2637-3858 UR - https://doi.org/10.11648/j.ijovs.20220701.12 AB - Background: Evaluating Foveal avascular zone by OCTA (Optical Coherence Tomography angiography) in diabetic patients, has a crucial role in early detection of pathophhsiological changes affecting the macular area, and has a pedective value for early retinal neuro degenerative changes. Materials and experiments: Aim: To evaluate dimensions of Foveal Avascular Zone (FAZ) at level of superficial and deep capillary plexuses (SCP/DCP) in patients with different grades of non proliferative diabetic retinopathy without Diabetic Macular Edema (DME) using OCTA. Eighty type II diabetes mellitus patients and 20 healthy control, ecxluding proliferative diabetic retinopathy and DME. Divided to four groups according to ETDRS Classification. All undewent: measurement of glycosylated hemoglobin level, standard Structural OCT for the macula and optic nerve head with OCTA for evaluation of FAZ in both SCP and DCP networks of all eyes using (Heidelberg engineering, OCT spectralis, Germany) (SD-OCT). Results: Mean FAZ in SCP in control group (0.32 ± 0.12) mm2 versus (0.44 ± 0.17) mm2 in patients` group, while FAZ IN DCP (0.23) mm2 ± 0.12 in controls versus (0.34 ± 0.16) mm2 in patients. There was a statistically significant wider FAZ in DR patients (P-value 0.003). Conclusion: Enlargement of FAZ in SCP and DCP in patients with moderate to severe NPDR without DME was detected using OCTA, Preceeded by reduction in thickness of ORL and GCC layer. This can be used to monitor the progression of the disease and to evaluate the response to treatment. VL - 7 IS - 1 ER -
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