Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review

Erick Andres Quiroz-Gonzalez; Miguel Angel Quiroz-Reyes; Cristina Gonzalez-Gonzalez; Roberto Loaeza-Castrejon; Luis Haro-Morlett; Armando Bautista-Barba; Emiliano Fulda-Graue; Federico Graue-Wiechers

doi:doi:10.11648/j.ijovs.20210604.23

Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review

Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Cristina Gonzalez-Gonzalez, Roberto Loaeza-Castrejon, Luis Haro-Morlett, Armando Bautista-Barba, Emiliano Fulda-Graue, Federico Graue-Wiechers

Published in International Journal of Ophthalmology & Visual Science (Volume 6, Issue 4)

Received: 2 December 2021 Accepted: 20 December 2021 Published: 29 December 2021

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Abstract

Background: Retinoblastoma is the most common intraocular mass in children—typically presenting in infants under 5 years of age—with a mean age of 24 months in unilateral cases, and 12 months in bilateral cases. Late-onset retinoblastoma and its presentation in adults is extremely rare; however, it should always be considered for the differential diagnosis of an intraocular mass originating from the retina. Due to the life-threatening nature of this disease, early diagnosis and prompt treatment are crucial for a good prognosis. Objective: A tumor case presentation and multidisciplinary study of a female young adult. Method: A case presentation study of a Hispanic teenager with a unilateral retinoblastoma and vitreous exudation resembling a large snowbank. The patient underwent complete ophthalmological examination and subsequent enucleation, with histopathological confirmation of retinoblastoma accompanied by chemotherapy. Conclusion: Retinoblastoma presenting as an intraocular mass in a young adult should always be considered as a differential diagnosis. Echography is crucial to obtaining a diagnosis, as well as dictating precise and adequate treatment. We review the literature regarding cases of retinoblastoma, demonstrating that most exhibited differentiated characteristics and were sporadic in nature; in most cases, the eye could not be saved. Review of late-onset retinoblastomas was therefore conducted to enrich our existing knowledge, as well as to prevent making the same mistakes when facing a similar difficult diagnosis.

Published in	International Journal of Ophthalmology & Visual Science (Volume 6, Issue 4)
DOI	10.11648/j.ijovs.20210604.23
Page(s)	267-272
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Retinoblastoma, Intraocular Mass, Leukocoria, Echography and Enucleation

References

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APA Style

Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Cristina Gonzalez-Gonzalez, Roberto Loaeza-Castrejon, Luis Haro-Morlett, et al. (2021). Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review. International Journal of Ophthalmology & Visual Science, 6(4), 267-272. https://doi.org/10.11648/j.ijovs.20210604.23

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ACS Style

Erick Andres Quiroz-Gonzalez; Miguel Angel Quiroz-Reyes; Cristina Gonzalez-Gonzalez; Roberto Loaeza-Castrejon; Luis Haro-Morlett, et al. Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review. Int. J. Ophthalmol. Vis. Sci. 2021, 6(4), 267-272. doi: 10.11648/j.ijovs.20210604.23

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AMA Style

Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Cristina Gonzalez-Gonzalez, Roberto Loaeza-Castrejon, Luis Haro-Morlett, et al. Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review. Int J Ophthalmol Vis Sci. 2021;6(4):267-272. doi: 10.11648/j.ijovs.20210604.23

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@article{10.11648/j.ijovs.20210604.23,
  author = {Erick Andres Quiroz-Gonzalez and Miguel Angel Quiroz-Reyes and Cristina Gonzalez-Gonzalez and Roberto Loaeza-Castrejon and Luis Haro-Morlett and Armando Bautista-Barba and Emiliano Fulda-Graue and Federico Graue-Wiechers},
  title = {Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {6},
  number = {4},
  pages = {267-272},
  doi = {10.11648/j.ijovs.20210604.23},
  url = {https://doi.org/10.11648/j.ijovs.20210604.23},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210604.23},
  abstract = {Background: Retinoblastoma is the most common intraocular mass in children—typically presenting in infants under 5 years of age—with a mean age of 24 months in unilateral cases, and 12 months in bilateral cases. Late-onset retinoblastoma and its presentation in adults is extremely rare; however, it should always be considered for the differential diagnosis of an intraocular mass originating from the retina. Due to the life-threatening nature of this disease, early diagnosis and prompt treatment are crucial for a good prognosis. Objective: A tumor case presentation and multidisciplinary study of a female young adult. Method: A case presentation study of a Hispanic teenager with a unilateral retinoblastoma and vitreous exudation resembling a large snowbank. The patient underwent complete ophthalmological examination and subsequent enucleation, with histopathological confirmation of retinoblastoma accompanied by chemotherapy. Conclusion: Retinoblastoma presenting as an intraocular mass in a young adult should always be considered as a differential diagnosis. Echography is crucial to obtaining a diagnosis, as well as dictating precise and adequate treatment. We review the literature regarding cases of retinoblastoma, demonstrating that most exhibited differentiated characteristics and were sporadic in nature; in most cases, the eye could not be saved. Review of late-onset retinoblastomas was therefore conducted to enrich our existing knowledge, as well as to prevent making the same mistakes when facing a similar difficult diagnosis.},
 year = {2021}
}

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TY  - JOUR
T1  - Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review
AU  - Erick Andres Quiroz-Gonzalez
AU  - Miguel Angel Quiroz-Reyes
AU  - Cristina Gonzalez-Gonzalez
AU  - Roberto Loaeza-Castrejon
AU  - Luis Haro-Morlett
AU  - Armando Bautista-Barba
AU  - Emiliano Fulda-Graue
AU  - Federico Graue-Wiechers
Y1  - 2021/12/29
PY  - 2021
N1  - https://doi.org/10.11648/j.ijovs.20210604.23
DO  - 10.11648/j.ijovs.20210604.23
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 267
EP  - 272
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20210604.23
AB  - Background: Retinoblastoma is the most common intraocular mass in children—typically presenting in infants under 5 years of age—with a mean age of 24 months in unilateral cases, and 12 months in bilateral cases. Late-onset retinoblastoma and its presentation in adults is extremely rare; however, it should always be considered for the differential diagnosis of an intraocular mass originating from the retina. Due to the life-threatening nature of this disease, early diagnosis and prompt treatment are crucial for a good prognosis. Objective: A tumor case presentation and multidisciplinary study of a female young adult. Method: A case presentation study of a Hispanic teenager with a unilateral retinoblastoma and vitreous exudation resembling a large snowbank. The patient underwent complete ophthalmological examination and subsequent enucleation, with histopathological confirmation of retinoblastoma accompanied by chemotherapy. Conclusion: Retinoblastoma presenting as an intraocular mass in a young adult should always be considered as a differential diagnosis. Echography is crucial to obtaining a diagnosis, as well as dictating precise and adequate treatment. We review the literature regarding cases of retinoblastoma, demonstrating that most exhibited differentiated characteristics and were sporadic in nature; in most cases, the eye could not be saved. Review of late-onset retinoblastomas was therefore conducted to enrich our existing knowledge, as well as to prevent making the same mistakes when facing a similar difficult diagnosis.
VL  - 6
IS  - 4
ER  -

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Author Information

Erick Andres Quiroz-Gonzalez

Ophthalmology Department, Institute of Ophthalmology, National Autonomous University of Mexico, Mexico City, Mexico
Miguel Angel Quiroz-Reyes

Retina Service, Institute of Ophthalmology, National Autonomous University of Mexico. Mexico City, Mexico
Cristina Gonzalez-Gonzalez

Ultrasonographic Department, Institute of Ophthalmology, National Autonomous University of Mexico, Mexico City, Mexico
Roberto Loaeza-Castrejon

Retina Service, Institute of Ophthalmology, National Autonomous University of Mexico. Mexico City, Mexico
Luis Haro-Morlett

Ophthalmology Department, Institute of Ophthalmology, National Autonomous University of Mexico, Mexico City, Mexico
Armando Bautista-Barba

Ophthalmology Department, Institute of Ophthalmology, National Autonomous University of Mexico, Mexico City, Mexico
Emiliano Fulda-Graue

Retina Service, Institute of Ophthalmology, National Autonomous University of Mexico. Mexico City, Mexico
Federico Graue-Wiechers

Retina Service, Institute of Ophthalmology, National Autonomous University of Mexico. Mexico City, Mexico

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APA Style

Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Cristina Gonzalez-Gonzalez, Roberto Loaeza-Castrejon, Luis Haro-Morlett, et al. (2021). Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review. International Journal of Ophthalmology & Visual Science, 6(4), 267-272. https://doi.org/10.11648/j.ijovs.20210604.23

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ACS Style

Erick Andres Quiroz-Gonzalez; Miguel Angel Quiroz-Reyes; Cristina Gonzalez-Gonzalez; Roberto Loaeza-Castrejon; Luis Haro-Morlett, et al. Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review. Int. J. Ophthalmol. Vis. Sci. 2021, 6(4), 267-272. doi: 10.11648/j.ijovs.20210604.23

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AMA Style

Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Cristina Gonzalez-Gonzalez, Roberto Loaeza-Castrejon, Luis Haro-Morlett, et al. Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review. Int J Ophthalmol Vis Sci. 2021;6(4):267-272. doi: 10.11648/j.ijovs.20210604.23

Copy | Download

@article{10.11648/j.ijovs.20210604.23,
  author = {Erick Andres Quiroz-Gonzalez and Miguel Angel Quiroz-Reyes and Cristina Gonzalez-Gonzalez and Roberto Loaeza-Castrejon and Luis Haro-Morlett and Armando Bautista-Barba and Emiliano Fulda-Graue and Federico Graue-Wiechers},
  title = {Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {6},
  number = {4},
  pages = {267-272},
  doi = {10.11648/j.ijovs.20210604.23},
  url = {https://doi.org/10.11648/j.ijovs.20210604.23},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210604.23},
  abstract = {Background: Retinoblastoma is the most common intraocular mass in children—typically presenting in infants under 5 years of age—with a mean age of 24 months in unilateral cases, and 12 months in bilateral cases. Late-onset retinoblastoma and its presentation in adults is extremely rare; however, it should always be considered for the differential diagnosis of an intraocular mass originating from the retina. Due to the life-threatening nature of this disease, early diagnosis and prompt treatment are crucial for a good prognosis. Objective: A tumor case presentation and multidisciplinary study of a female young adult. Method: A case presentation study of a Hispanic teenager with a unilateral retinoblastoma and vitreous exudation resembling a large snowbank. The patient underwent complete ophthalmological examination and subsequent enucleation, with histopathological confirmation of retinoblastoma accompanied by chemotherapy. Conclusion: Retinoblastoma presenting as an intraocular mass in a young adult should always be considered as a differential diagnosis. Echography is crucial to obtaining a diagnosis, as well as dictating precise and adequate treatment. We review the literature regarding cases of retinoblastoma, demonstrating that most exhibited differentiated characteristics and were sporadic in nature; in most cases, the eye could not be saved. Review of late-onset retinoblastomas was therefore conducted to enrich our existing knowledge, as well as to prevent making the same mistakes when facing a similar difficult diagnosis.},
 year = {2021}
}

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TY  - JOUR
T1  - Unilateral Retinoblastoma Presentation in a Latin-American Teenager: A Case Report and Literature Review
AU  - Erick Andres Quiroz-Gonzalez
AU  - Miguel Angel Quiroz-Reyes
AU  - Cristina Gonzalez-Gonzalez
AU  - Roberto Loaeza-Castrejon
AU  - Luis Haro-Morlett
AU  - Armando Bautista-Barba
AU  - Emiliano Fulda-Graue
AU  - Federico Graue-Wiechers
Y1  - 2021/12/29
PY  - 2021
N1  - https://doi.org/10.11648/j.ijovs.20210604.23
DO  - 10.11648/j.ijovs.20210604.23
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 267
EP  - 272
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20210604.23
AB  - Background: Retinoblastoma is the most common intraocular mass in children—typically presenting in infants under 5 years of age—with a mean age of 24 months in unilateral cases, and 12 months in bilateral cases. Late-onset retinoblastoma and its presentation in adults is extremely rare; however, it should always be considered for the differential diagnosis of an intraocular mass originating from the retina. Due to the life-threatening nature of this disease, early diagnosis and prompt treatment are crucial for a good prognosis. Objective: A tumor case presentation and multidisciplinary study of a female young adult. Method: A case presentation study of a Hispanic teenager with a unilateral retinoblastoma and vitreous exudation resembling a large snowbank. The patient underwent complete ophthalmological examination and subsequent enucleation, with histopathological confirmation of retinoblastoma accompanied by chemotherapy. Conclusion: Retinoblastoma presenting as an intraocular mass in a young adult should always be considered as a differential diagnosis. Echography is crucial to obtaining a diagnosis, as well as dictating precise and adequate treatment. We review the literature regarding cases of retinoblastoma, demonstrating that most exhibited differentiated characteristics and were sporadic in nature; in most cases, the eye could not be saved. Review of late-onset retinoblastomas was therefore conducted to enrich our existing knowledge, as well as to prevent making the same mistakes when facing a similar difficult diagnosis.
VL  - 6
IS  - 4
ER  -

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