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Clinical Profile of COVID Patients During Recovery Phase at Tertiary Eye Care Centre in South India

Received: 22 September 2021    Accepted: 11 October 2021    Published: 21 October 2021
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Abstract

BACK GROUND: Though Corona virus -19 first reported in china, Indian population in urban as well as rural areas were badly effected during second wave with involvement of various ocular structures, some patients lost vision due to retinal vascular occlusions, some patients required enucleation and orbital exenteration due to fungus infections of the eye. Patients reported with different ocular disorders were documented and intervened, were included in this study. We tried to understand whether these manifestations were due to Corona Virus or due to immune compression because of systemic disorders in Corona patients treated with oral steroids and unsterile oxygen support. Aim: Purpose is to study the various clinical manifestations noted in COVID-19 patients during second wave after treatment while recovering from the acute illness. Methods: Retrospective interventional study done at tertiary eye care centre. Duration of the study is 3months from April 2021 to June 2021.500 patients were presented to our tertiary eye care centre with various clinical manifestations. All patients underwent detailed systemic and ocular examination. Patients after treatment for COVID-19 at various hospitals across the country were presented to our institute with many opportunistic infections. Apart from history BCVA, Slit Lamp examination, fundus examination, OCT, Fundus Fluorescein Angiography and B Scan done in patients where media was hazy, documentation done in all cases. Systemic examination and other investigation like RT PCR for corona virus was done in all patients. Patients presented with orbital involvement were advised CT Scan orbit. Results: Most of the patients were badly effected with many ocular complications, very few patients could maintain normal visual acuity. Many patients developed diabetes mellitus, probably they were pre diabetics manifested after use of oral steroids. Conclusion: Second wave in India increased the mortality and also effected the quality of the life in survivors. Fatality was high due to various ocular complications in all individuals irrespective of age and immune status.

Published in International Journal of Ophthalmology & Visual Science (Volume 6, Issue 4)
DOI 10.11648/j.ijovs.20210604.14
Page(s) 203-208
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

COVID-19, Crao, Cotton Wool Spots, Vitritis, Retinitis, Endophthalmitis, Panophthalmitis, RBN, AION

References
[1] Parul Chawla Gupta1, Praveen Kumar-M2 & Jagat Ram. COVID-19 pandemic from an ophthalmology point of view. Indian J Med Res 151, May 2020, pp 411-418 DOI: 10.4103/ijmr.IJMR_1369_20.
[2] Raffaele Nuzzi, Luigi Ludovico Carucci & Flavia Tripoli. COVID-19 and ocular implications: an update. Nuzzi et al. Journal of Ophthalmic Inflammation and Infection (2020) 10: 20 https://doi.org/10.1186/s12348-020-00212-4.
[3] Senanayake PS, Drazba J, Shadrach K et al (2007) Angiotensin II and its receptor subtypes in the human retina. Invest Ophthalmol Vis Sci 48: 3301–3311 6.
[4] Zhou P, Yang X-L, Wang X-G et al (2020) A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 579: 270–273.
[5] Huang C, Wang Y, Li X et al (2020) Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395: 497–506 3.
[6] Cascella M, Rajnik M, Aleem A, Dulebohn SC, Di Napoli R. StatPearls [Internet]. StatPearls Publishing; Treasure Island (FL): Apr 20, 2021. Features, Evaluation, and Treatment of Coronavirus (COVID-19).
[7] Harrison AG, Lin T, Wang P. Mechanisms of SARS-CoV-2 Transmission and Pathogenesis. Trends Immunol. 2020 Dec; 41 (12): 1100-1115.
[8] Chen L, Liu M, Zhang Z, Qiao K, Huang T, Chen M, et al. Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease. Br J Ophthalmol 2020; 104: 748‑51.
[9] Cumberworth VL, Sudderick RM, Mackay IS. Major complications of functional endoscopic sinus surgery. Clin Otolaryngol Allied Sci. 1994; 19 (3): 248-253.
[10] Harris A, Jonescu-Cuypers CP, Kagemann L, Ciulla TA, Krieglstein GK. Atlas of Ocular Blood Flow: Vascular Anatomy, Pathophysiology, and Metabolism. Philadelphia, PA: Butterworth Heinemann; 2003.
[11] Tomaso Caporossi, DanielaBacherini, Ruggero Tartaro et al. Retinal findings in patients affected by COVID19intubated in an intensive care unit. Acta Ophthalmolo gica 2020.
[12] Magro C, Mulvey JJ, Berlin D, et al. Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases [published online ahead of print, 2020 Apr 15]. Transl Res. 2020; S1931-5244 (20) 30070-0. doi: 10.1016/j.trsl.2020.04.00.
[13] Xun Ding, Jia Xu, Jun Zhou, and Qingyun Long. Chest CT findings of COVID-19 pneumonia by duration of symptoms. Eur J Radiol. 2020 Jun; 127: 109009. Published online 2020 Apr 18. doi: 10.1016/j.ejrad.2020.109009.
[14] Federica Bertoli, Daniele Veritti, Carla Danese, Francesco Samassa et al. Ocular Findings in COVID-19 Patients: A Review of Direct Manifestations and Indirect Effects on the Eye. Journal of Ophthalmology Volume 2020, Article ID 4827304, 9 pages.
[15] Sunny Chi Lik Au, MBChB, and Callie Ka Li Ko. Central Retinal Artery Occlusion in Patients with COVID-19: Imaging for Underlying Causes. Radiology on February 16, 2021.
[16] Antônio Marcos da Silva Catharino, Marco Antônio Orsini Neves, Nicolle dos Santos Moraes Nunes et al. COVID-19 Related Optic Neuritis: Case Report. Case Report Article id: JCNN-20-10.
[17] Barbara Burgos Blasco, Noemi Güemes Villahoz, Juan Donate Et al. Optic nerve analysis in COVID-19 patients. J Med Virol. 2021; 93: 190–191.
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  • APA Style

    Aliya Sultana, Sana Fathima, Amatul Raheem Sara. (2021). Clinical Profile of COVID Patients During Recovery Phase at Tertiary Eye Care Centre in South India. International Journal of Ophthalmology & Visual Science, 6(4), 203-208. https://doi.org/10.11648/j.ijovs.20210604.14

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    ACS Style

    Aliya Sultana; Sana Fathima; Amatul Raheem Sara. Clinical Profile of COVID Patients During Recovery Phase at Tertiary Eye Care Centre in South India. Int. J. Ophthalmol. Vis. Sci. 2021, 6(4), 203-208. doi: 10.11648/j.ijovs.20210604.14

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    AMA Style

    Aliya Sultana, Sana Fathima, Amatul Raheem Sara. Clinical Profile of COVID Patients During Recovery Phase at Tertiary Eye Care Centre in South India. Int J Ophthalmol Vis Sci. 2021;6(4):203-208. doi: 10.11648/j.ijovs.20210604.14

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  • @article{10.11648/j.ijovs.20210604.14,
      author = {Aliya Sultana and Sana Fathima and Amatul Raheem Sara},
      title = {Clinical Profile of COVID Patients During Recovery Phase at Tertiary Eye Care Centre in South India},
      journal = {International Journal of Ophthalmology & Visual Science},
      volume = {6},
      number = {4},
      pages = {203-208},
      doi = {10.11648/j.ijovs.20210604.14},
      url = {https://doi.org/10.11648/j.ijovs.20210604.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210604.14},
      abstract = {BACK GROUND: Though Corona virus -19 first reported in china, Indian population in urban as well as rural areas were badly effected during second wave with involvement of various ocular structures, some patients lost vision due to retinal vascular occlusions, some patients required enucleation and orbital exenteration due to fungus infections of the eye. Patients reported with different ocular disorders were documented and intervened, were included in this study. We tried to understand whether these manifestations were due to Corona Virus or due to immune compression because of systemic disorders in Corona patients treated with oral steroids and unsterile oxygen support. Aim: Purpose is to study the various clinical manifestations noted in COVID-19 patients during second wave after treatment while recovering from the acute illness. Methods: Retrospective interventional study done at tertiary eye care centre. Duration of the study is 3months from April 2021 to June 2021.500 patients were presented to our tertiary eye care centre with various clinical manifestations. All patients underwent detailed systemic and ocular examination. Patients after treatment for COVID-19 at various hospitals across the country were presented to our institute with many opportunistic infections. Apart from history BCVA, Slit Lamp examination, fundus examination, OCT, Fundus Fluorescein Angiography and B Scan done in patients where media was hazy, documentation done in all cases. Systemic examination and other investigation like RT PCR for corona virus was done in all patients. Patients presented with orbital involvement were advised CT Scan orbit. Results: Most of the patients were badly effected with many ocular complications, very few patients could maintain normal visual acuity. Many patients developed diabetes mellitus, probably they were pre diabetics manifested after use of oral steroids. Conclusion: Second wave in India increased the mortality and also effected the quality of the life in survivors. Fatality was high due to various ocular complications in all individuals irrespective of age and immune status.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Clinical Profile of COVID Patients During Recovery Phase at Tertiary Eye Care Centre in South India
    AU  - Aliya Sultana
    AU  - Sana Fathima
    AU  - Amatul Raheem Sara
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    AB  - BACK GROUND: Though Corona virus -19 first reported in china, Indian population in urban as well as rural areas were badly effected during second wave with involvement of various ocular structures, some patients lost vision due to retinal vascular occlusions, some patients required enucleation and orbital exenteration due to fungus infections of the eye. Patients reported with different ocular disorders were documented and intervened, were included in this study. We tried to understand whether these manifestations were due to Corona Virus or due to immune compression because of systemic disorders in Corona patients treated with oral steroids and unsterile oxygen support. Aim: Purpose is to study the various clinical manifestations noted in COVID-19 patients during second wave after treatment while recovering from the acute illness. Methods: Retrospective interventional study done at tertiary eye care centre. Duration of the study is 3months from April 2021 to June 2021.500 patients were presented to our tertiary eye care centre with various clinical manifestations. All patients underwent detailed systemic and ocular examination. Patients after treatment for COVID-19 at various hospitals across the country were presented to our institute with many opportunistic infections. Apart from history BCVA, Slit Lamp examination, fundus examination, OCT, Fundus Fluorescein Angiography and B Scan done in patients where media was hazy, documentation done in all cases. Systemic examination and other investigation like RT PCR for corona virus was done in all patients. Patients presented with orbital involvement were advised CT Scan orbit. Results: Most of the patients were badly effected with many ocular complications, very few patients could maintain normal visual acuity. Many patients developed diabetes mellitus, probably they were pre diabetics manifested after use of oral steroids. Conclusion: Second wave in India increased the mortality and also effected the quality of the life in survivors. Fatality was high due to various ocular complications in all individuals irrespective of age and immune status.
    VL  - 6
    IS  - 4
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Author Information
  • Vitreo Retina Department, Sarojini Devi Eye Hospital, Osmania Medical College, Hyderabad, India

  • Vitreo Retina Department, Sarojini Devi Eye Hospital, Osmania Medical College, Hyderabad, India

  • Vitreo Retina Department, Sarojini Devi Eye Hospital, Osmania Medical College, Hyderabad, India

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