Peripheral ulcerative keratitis (PUK) is an aggressive, potentially sight-threatening cause for peripheral corneal thinning. It may precede the diagnosis of the systemic condition and therefore these cases require urgent investigation. A 43-year-old woman presented with bilateral tearing and ocular pain persisting for 7 months. Visual acuity was 6/6 in both eyes. On biomicroscopic examination, presence of crescent shaped corneal ulcer with perilesional haziness. A tear film study demonstrated decreased Schirmer test results (5mm in both eyes) and tear film break-up time (5 sec in both eyes). The interrogation and the patient revealed he had recurrent skin lesions in both legs with chronic itching, and recurrent oral and genital ulcers healing spontaneously. The diagnosis of Behcet disease was proposed. Pathergy test was negative, HLA B51 was positif. Systemic therapy was started with colchicine at a dose of 2mg/day. Eye drops and systemic prednisolone at 1mg/kg/day was continued with progressive decrease. The follow up at 3 months and 6 months showed no signs of recurrence of ulceration in both eyes. Corneal manifestation has rarely been reported in Behçet’s disease. Combined intraocular anterior and posterior segment inflammation are most common features of ocular Behçet disease. Collaborative management of ophthalmic patients having systemic illness along with internists improves overall outcomes and prevents morbidity in such patients.
| Published in | International Journal of Ophthalmology & Visual Science (Volume 6, Issue 2) |
| DOI | 10.11648/j.ijovs.20210602.23 |
| Page(s) | 150-153 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Ocular Inflammation, Corneal Ulcer, Amniotic Membrane, Behcet Disease, PUK
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APA Style
Belghmaidi Sarah, Darfaoui Zineb, Hajji Ibtissam, Moutaouakil Abdeljalil. (2021). A Case of Bilateral Peripheral Ulcerative Keratitis. International Journal of Ophthalmology & Visual Science, 6(2), 150-153. https://doi.org/10.11648/j.ijovs.20210602.23
ACS Style
Belghmaidi Sarah; Darfaoui Zineb; Hajji Ibtissam; Moutaouakil Abdeljalil. A Case of Bilateral Peripheral Ulcerative Keratitis. Int. J. Ophthalmol. Vis. Sci. 2021, 6(2), 150-153. doi: 10.11648/j.ijovs.20210602.23
AMA Style
Belghmaidi Sarah, Darfaoui Zineb, Hajji Ibtissam, Moutaouakil Abdeljalil. A Case of Bilateral Peripheral Ulcerative Keratitis. Int J Ophthalmol Vis Sci. 2021;6(2):150-153. doi: 10.11648/j.ijovs.20210602.23
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Download@article{10.11648/j.ijovs.20210602.23,
author = {Belghmaidi Sarah and Darfaoui Zineb and Hajji Ibtissam and Moutaouakil Abdeljalil},
title = {A Case of Bilateral Peripheral Ulcerative Keratitis},
journal = {International Journal of Ophthalmology & Visual Science},
volume = {6},
number = {2},
pages = {150-153},
doi = {10.11648/j.ijovs.20210602.23},
url = {https://doi.org/10.11648/j.ijovs.20210602.23},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210602.23},
abstract = {Peripheral ulcerative keratitis (PUK) is an aggressive, potentially sight-threatening cause for peripheral corneal thinning. It may precede the diagnosis of the systemic condition and therefore these cases require urgent investigation. A 43-year-old woman presented with bilateral tearing and ocular pain persisting for 7 months. Visual acuity was 6/6 in both eyes. On biomicroscopic examination, presence of crescent shaped corneal ulcer with perilesional haziness. A tear film study demonstrated decreased Schirmer test results (5mm in both eyes) and tear film break-up time (5 sec in both eyes). The interrogation and the patient revealed he had recurrent skin lesions in both legs with chronic itching, and recurrent oral and genital ulcers healing spontaneously. The diagnosis of Behcet disease was proposed. Pathergy test was negative, HLA B51 was positif. Systemic therapy was started with colchicine at a dose of 2mg/day. Eye drops and systemic prednisolone at 1mg/kg/day was continued with progressive decrease. The follow up at 3 months and 6 months showed no signs of recurrence of ulceration in both eyes. Corneal manifestation has rarely been reported in Behçet’s disease. Combined intraocular anterior and posterior segment inflammation are most common features of ocular Behçet disease. Collaborative management of ophthalmic patients having systemic illness along with internists improves overall outcomes and prevents morbidity in such patients.},
year = {2021}
}
TY - JOUR T1 - A Case of Bilateral Peripheral Ulcerative Keratitis AU - Belghmaidi Sarah AU - Darfaoui Zineb AU - Hajji Ibtissam AU - Moutaouakil Abdeljalil Y1 - 2021/06/30 PY - 2021 N1 - https://doi.org/10.11648/j.ijovs.20210602.23 DO - 10.11648/j.ijovs.20210602.23 T2 - International Journal of Ophthalmology & Visual Science JF - International Journal of Ophthalmology & Visual Science JO - International Journal of Ophthalmology & Visual Science SP - 150 EP - 153 PB - Science Publishing Group SN - 2637-3858 UR - https://doi.org/10.11648/j.ijovs.20210602.23 AB - Peripheral ulcerative keratitis (PUK) is an aggressive, potentially sight-threatening cause for peripheral corneal thinning. It may precede the diagnosis of the systemic condition and therefore these cases require urgent investigation. A 43-year-old woman presented with bilateral tearing and ocular pain persisting for 7 months. Visual acuity was 6/6 in both eyes. On biomicroscopic examination, presence of crescent shaped corneal ulcer with perilesional haziness. A tear film study demonstrated decreased Schirmer test results (5mm in both eyes) and tear film break-up time (5 sec in both eyes). The interrogation and the patient revealed he had recurrent skin lesions in both legs with chronic itching, and recurrent oral and genital ulcers healing spontaneously. The diagnosis of Behcet disease was proposed. Pathergy test was negative, HLA B51 was positif. Systemic therapy was started with colchicine at a dose of 2mg/day. Eye drops and systemic prednisolone at 1mg/kg/day was continued with progressive decrease. The follow up at 3 months and 6 months showed no signs of recurrence of ulceration in both eyes. Corneal manifestation has rarely been reported in Behçet’s disease. Combined intraocular anterior and posterior segment inflammation are most common features of ocular Behçet disease. Collaborative management of ophthalmic patients having systemic illness along with internists improves overall outcomes and prevents morbidity in such patients. VL - 6 IS - 2 ER -
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