Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences

Olesia Zavoloka; Pavlo Bezditko

doi:doi:10.11648/j.ijovs.20210602.19

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Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences

Olesia Zavoloka, Pavlo Bezditko

Published in International Journal of Ophthalmology & Visual Science (Volume 6, Issue 2)

Received: 26 May 2021 Accepted: 8 June 2021 Published: 15 June 2021

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Abstract

The purpose was to define the peculiarities of the course and consequences of bacterial keratitis in patients with type 1 diabetes mellitus (DM1) depending on the stage of its severity. Methods. 34 DM1 patients (34 eyes) with bacterial keratitis whose initial bacteriological examination revealed pathogen sensitivity to the antibiotic ofloxacin participated in this study. All patients were treated topically with ofloxacin, antiseptics, repairing agents, antioxidants, mydriatics, artificial tears and systemically with anti-inflammatory agents. Patients were divided into two groups according to the severity of bacterial keratitis at the first visit. Research methods were as follows: visual acuity, tonometry, slit-lamp biomicroscopy of anterior and posterior eye segments, fluorescein dye test, non-contact corneal esthesiometry, anterior eye OCT and bacteriological studies. Results. Compared to the stage I, DM1 patients with stage II severity bacterial keratitis showed higher degree of pericorneal injection, larger and deeper corneal ulcer defect, deeper corneal infiltration and edema, higher mean corneal sensitivity threshold at all time point of the study, p<0.05. DM1 patients with stage II severity bacterial keratitis were more prone for longer duration of the disease and worse consequences. Therefore, on day 24 in 33.3% diabetic patients with stage II severity bacterial keratitis corneal ulcer was not found to be healed. Conclusions. Course and consequences of bacterial keratitis in type 1 diabetes mellitus patients depend on the stage of severity of bacterial keratitis.

Published in	International Journal of Ophthalmology & Visual Science (Volume 6, Issue 2)
DOI	10.11648/j.ijovs.20210602.19
Page(s)	115-121
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Diabetes Mellitus, Bacterial Keratitis, Course of Bacterial Keratitis Course, Consequences of Bacterial Keratitis

References

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APA Style

Olesia Zavoloka, Pavlo Bezditko. (2021). Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences. International Journal of Ophthalmology & Visual Science, 6(2), 115-121. https://doi.org/10.11648/j.ijovs.20210602.19

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ACS Style

Olesia Zavoloka; Pavlo Bezditko. Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences. Int. J. Ophthalmol. Vis. Sci. 2021, 6(2), 115-121. doi: 10.11648/j.ijovs.20210602.19

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AMA Style

Olesia Zavoloka, Pavlo Bezditko. Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences. Int J Ophthalmol Vis Sci. 2021;6(2):115-121. doi: 10.11648/j.ijovs.20210602.19

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@article{10.11648/j.ijovs.20210602.19,
  author = {Olesia Zavoloka and Pavlo Bezditko},
  title = {Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {6},
  number = {2},
  pages = {115-121},
  doi = {10.11648/j.ijovs.20210602.19},
  url = {https://doi.org/10.11648/j.ijovs.20210602.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210602.19},
  abstract = {The purpose was to define the peculiarities of the course and consequences of bacterial keratitis in patients with type 1 diabetes mellitus (DM1) depending on the stage of its severity. Methods. 34 DM1 patients (34 eyes) with bacterial keratitis whose initial bacteriological examination revealed pathogen sensitivity to the antibiotic ofloxacin participated in this study. All patients were treated topically with ofloxacin, antiseptics, repairing agents, antioxidants, mydriatics, artificial tears and systemically with anti-inflammatory agents. Patients were divided into two groups according to the severity of bacterial keratitis at the first visit. Research methods were as follows: visual acuity, tonometry, slit-lamp biomicroscopy of anterior and posterior eye segments, fluorescein dye test, non-contact corneal esthesiometry, anterior eye OCT and bacteriological studies. Results. Compared to the stage I, DM1 patients with stage II severity bacterial keratitis showed higher degree of pericorneal injection, larger and deeper corneal ulcer defect, deeper corneal infiltration and edema, higher mean corneal sensitivity threshold at all time point of the study, p Conclusions. Course and consequences of bacterial keratitis in type 1 diabetes mellitus patients depend on the stage of severity of bacterial keratitis.},
 year = {2021}
}

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TY  - JOUR
T1  - Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences
AU  - Olesia Zavoloka
AU  - Pavlo Bezditko
Y1  - 2021/06/15
PY  - 2021
N1  - https://doi.org/10.11648/j.ijovs.20210602.19
DO  - 10.11648/j.ijovs.20210602.19
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 115
EP  - 121
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20210602.19
AB  - The purpose was to define the peculiarities of the course and consequences of bacterial keratitis in patients with type 1 diabetes mellitus (DM1) depending on the stage of its severity. Methods. 34 DM1 patients (34 eyes) with bacterial keratitis whose initial bacteriological examination revealed pathogen sensitivity to the antibiotic ofloxacin participated in this study. All patients were treated topically with ofloxacin, antiseptics, repairing agents, antioxidants, mydriatics, artificial tears and systemically with anti-inflammatory agents. Patients were divided into two groups according to the severity of bacterial keratitis at the first visit. Research methods were as follows: visual acuity, tonometry, slit-lamp biomicroscopy of anterior and posterior eye segments, fluorescein dye test, non-contact corneal esthesiometry, anterior eye OCT and bacteriological studies. Results. Compared to the stage I, DM1 patients with stage II severity bacterial keratitis showed higher degree of pericorneal injection, larger and deeper corneal ulcer defect, deeper corneal infiltration and edema, higher mean corneal sensitivity threshold at all time point of the study, p Conclusions. Course and consequences of bacterial keratitis in type 1 diabetes mellitus patients depend on the stage of severity of bacterial keratitis.
VL  - 6
IS  - 2
ER  -

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Author Information

Olesia Zavoloka

Department of Ophthalmology, Kharkiv National Medical University, Kharkiv, Ukraine
Pavlo Bezditko

Department of Ophthalmology, Kharkiv National Medical University, Kharkiv, Ukraine

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APA Style

Olesia Zavoloka, Pavlo Bezditko. (2021). Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences. International Journal of Ophthalmology & Visual Science, 6(2), 115-121. https://doi.org/10.11648/j.ijovs.20210602.19

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ACS Style

Olesia Zavoloka; Pavlo Bezditko. Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences. Int. J. Ophthalmol. Vis. Sci. 2021, 6(2), 115-121. doi: 10.11648/j.ijovs.20210602.19

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AMA Style

Olesia Zavoloka, Pavlo Bezditko. Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences. Int J Ophthalmol Vis Sci. 2021;6(2):115-121. doi: 10.11648/j.ijovs.20210602.19

Copy | Download

@article{10.11648/j.ijovs.20210602.19,
  author = {Olesia Zavoloka and Pavlo Bezditko},
  title = {Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {6},
  number = {2},
  pages = {115-121},
  doi = {10.11648/j.ijovs.20210602.19},
  url = {https://doi.org/10.11648/j.ijovs.20210602.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210602.19},
  abstract = {The purpose was to define the peculiarities of the course and consequences of bacterial keratitis in patients with type 1 diabetes mellitus (DM1) depending on the stage of its severity. Methods. 34 DM1 patients (34 eyes) with bacterial keratitis whose initial bacteriological examination revealed pathogen sensitivity to the antibiotic ofloxacin participated in this study. All patients were treated topically with ofloxacin, antiseptics, repairing agents, antioxidants, mydriatics, artificial tears and systemically with anti-inflammatory agents. Patients were divided into two groups according to the severity of bacterial keratitis at the first visit. Research methods were as follows: visual acuity, tonometry, slit-lamp biomicroscopy of anterior and posterior eye segments, fluorescein dye test, non-contact corneal esthesiometry, anterior eye OCT and bacteriological studies. Results. Compared to the stage I, DM1 patients with stage II severity bacterial keratitis showed higher degree of pericorneal injection, larger and deeper corneal ulcer defect, deeper corneal infiltration and edema, higher mean corneal sensitivity threshold at all time point of the study, p Conclusions. Course and consequences of bacterial keratitis in type 1 diabetes mellitus patients depend on the stage of severity of bacterial keratitis.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences
AU  - Olesia Zavoloka
AU  - Pavlo Bezditko
Y1  - 2021/06/15
PY  - 2021
N1  - https://doi.org/10.11648/j.ijovs.20210602.19
DO  - 10.11648/j.ijovs.20210602.19
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 115
EP  - 121
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20210602.19
AB  - The purpose was to define the peculiarities of the course and consequences of bacterial keratitis in patients with type 1 diabetes mellitus (DM1) depending on the stage of its severity. Methods. 34 DM1 patients (34 eyes) with bacterial keratitis whose initial bacteriological examination revealed pathogen sensitivity to the antibiotic ofloxacin participated in this study. All patients were treated topically with ofloxacin, antiseptics, repairing agents, antioxidants, mydriatics, artificial tears and systemically with anti-inflammatory agents. Patients were divided into two groups according to the severity of bacterial keratitis at the first visit. Research methods were as follows: visual acuity, tonometry, slit-lamp biomicroscopy of anterior and posterior eye segments, fluorescein dye test, non-contact corneal esthesiometry, anterior eye OCT and bacteriological studies. Results. Compared to the stage I, DM1 patients with stage II severity bacterial keratitis showed higher degree of pericorneal injection, larger and deeper corneal ulcer defect, deeper corneal infiltration and edema, higher mean corneal sensitivity threshold at all time point of the study, p Conclusions. Course and consequences of bacterial keratitis in type 1 diabetes mellitus patients depend on the stage of severity of bacterial keratitis.
VL  - 6
IS  - 2
ER  -

Copy | Download