Purpose-To report a rare presentation of Vogt-Koyanagi-Harada (VKH) disease in a 55 year old female patient with unilateral limbal stem cell deficiency (LSCD) with corneal perforation. Observations-Patient presented to the out patient department with recurrent episodes of watering, pain, redness in the left eye. Examination revealed LSCD with areas of pannus and infiltration. She was treated medically. Patient came back after a year with a corneal perforation in her left eye. The perforation was sealed using cyanoacrylate glue. Six weeks later, she presented with a drop in vision in both eyes. Optical Coherence Tomography (OCT) in both eyes showed multiple sub retinal fluid pockets and Fundus Fluorescein Angiography (FFA) revealed multiple pinpoint leakages typical of Harada disease. The patient was investigated for systemic associations, which were found to be normal. She was managed with tapering doses of oral steroids. OCT showed resolution of fluid pockets at one month. There was a good control of the disease, with no signs of recurrence at 6 months follow up. Conclusion-The clinical association between the two entities has not been published in literature till date. Further data or reports on such cases would help throw light on any possible association between LSCD and VKH disease.
| Published in | International Journal of Ophthalmology & Visual Science (Volume 6, Issue 2) |
| DOI | 10.11648/j.ijovs.20210602.12 |
| Page(s) | 72-74 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Vogt-Koyanagi Harada Disease, Limbal Stem Cell Deficiency, Corneal Perforation
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APA Style
Shreesha Kumar Kodavoor, Soundarya Balajee, Ramamurthy Dandapani, Muralidhar Rajamani, Thenarasun Seethalakshmi Asaithambi. (2021). A Rare Presentation of Bilateral Vogt-Koyanagi-Harada (VKH) Disease in a Patient with Unilateral Limbal Stem Cell Deficiency (LSCD) with Corneal Perforation. International Journal of Ophthalmology & Visual Science, 6(2), 72-74. https://doi.org/10.11648/j.ijovs.20210602.12
ACS Style
Shreesha Kumar Kodavoor; Soundarya Balajee; Ramamurthy Dandapani; Muralidhar Rajamani; Thenarasun Seethalakshmi Asaithambi. A Rare Presentation of Bilateral Vogt-Koyanagi-Harada (VKH) Disease in a Patient with Unilateral Limbal Stem Cell Deficiency (LSCD) with Corneal Perforation. Int. J. Ophthalmol. Vis. Sci. 2021, 6(2), 72-74. doi: 10.11648/j.ijovs.20210602.12
AMA Style
Shreesha Kumar Kodavoor, Soundarya Balajee, Ramamurthy Dandapani, Muralidhar Rajamani, Thenarasun Seethalakshmi Asaithambi. A Rare Presentation of Bilateral Vogt-Koyanagi-Harada (VKH) Disease in a Patient with Unilateral Limbal Stem Cell Deficiency (LSCD) with Corneal Perforation. Int J Ophthalmol Vis Sci. 2021;6(2):72-74. doi: 10.11648/j.ijovs.20210602.12
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Download@article{10.11648/j.ijovs.20210602.12,
author = {Shreesha Kumar Kodavoor and Soundarya Balajee and Ramamurthy Dandapani and Muralidhar Rajamani and Thenarasun Seethalakshmi Asaithambi},
title = {A Rare Presentation of Bilateral Vogt-Koyanagi-Harada (VKH) Disease in a Patient with Unilateral Limbal Stem Cell Deficiency (LSCD) with Corneal Perforation},
journal = {International Journal of Ophthalmology & Visual Science},
volume = {6},
number = {2},
pages = {72-74},
doi = {10.11648/j.ijovs.20210602.12},
url = {https://doi.org/10.11648/j.ijovs.20210602.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210602.12},
abstract = {Purpose-To report a rare presentation of Vogt-Koyanagi-Harada (VKH) disease in a 55 year old female patient with unilateral limbal stem cell deficiency (LSCD) with corneal perforation. Observations-Patient presented to the out patient department with recurrent episodes of watering, pain, redness in the left eye. Examination revealed LSCD with areas of pannus and infiltration. She was treated medically. Patient came back after a year with a corneal perforation in her left eye. The perforation was sealed using cyanoacrylate glue. Six weeks later, she presented with a drop in vision in both eyes. Optical Coherence Tomography (OCT) in both eyes showed multiple sub retinal fluid pockets and Fundus Fluorescein Angiography (FFA) revealed multiple pinpoint leakages typical of Harada disease. The patient was investigated for systemic associations, which were found to be normal. She was managed with tapering doses of oral steroids. OCT showed resolution of fluid pockets at one month. There was a good control of the disease, with no signs of recurrence at 6 months follow up. Conclusion-The clinical association between the two entities has not been published in literature till date. Further data or reports on such cases would help throw light on any possible association between LSCD and VKH disease.},
year = {2021}
}
TY - JOUR T1 - A Rare Presentation of Bilateral Vogt-Koyanagi-Harada (VKH) Disease in a Patient with Unilateral Limbal Stem Cell Deficiency (LSCD) with Corneal Perforation AU - Shreesha Kumar Kodavoor AU - Soundarya Balajee AU - Ramamurthy Dandapani AU - Muralidhar Rajamani AU - Thenarasun Seethalakshmi Asaithambi Y1 - 2021/04/16 PY - 2021 N1 - https://doi.org/10.11648/j.ijovs.20210602.12 DO - 10.11648/j.ijovs.20210602.12 T2 - International Journal of Ophthalmology & Visual Science JF - International Journal of Ophthalmology & Visual Science JO - International Journal of Ophthalmology & Visual Science SP - 72 EP - 74 PB - Science Publishing Group SN - 2637-3858 UR - https://doi.org/10.11648/j.ijovs.20210602.12 AB - Purpose-To report a rare presentation of Vogt-Koyanagi-Harada (VKH) disease in a 55 year old female patient with unilateral limbal stem cell deficiency (LSCD) with corneal perforation. Observations-Patient presented to the out patient department with recurrent episodes of watering, pain, redness in the left eye. Examination revealed LSCD with areas of pannus and infiltration. She was treated medically. Patient came back after a year with a corneal perforation in her left eye. The perforation was sealed using cyanoacrylate glue. Six weeks later, she presented with a drop in vision in both eyes. Optical Coherence Tomography (OCT) in both eyes showed multiple sub retinal fluid pockets and Fundus Fluorescein Angiography (FFA) revealed multiple pinpoint leakages typical of Harada disease. The patient was investigated for systemic associations, which were found to be normal. She was managed with tapering doses of oral steroids. OCT showed resolution of fluid pockets at one month. There was a good control of the disease, with no signs of recurrence at 6 months follow up. Conclusion-The clinical association between the two entities has not been published in literature till date. Further data or reports on such cases would help throw light on any possible association between LSCD and VKH disease. VL - 6 IS - 2 ER -
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