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Co-infection Pulmonary Tuberculosis and Severe COVID-19 in a Pregnant Woman at the University Hospital of Kinshasa: A Case Report

Received: 14 July 2021    Accepted: 28 July 2021    Published: 4 August 2021
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Abstract

Background: To date, world widely, only a couple of papers have reported the association between pulmonary tuberculosis, Coronavirus disease 2019 (COVID-19) and pregnancy, and none of these reports was from sub-Saharan Africa where tuberculosis is endemic. Objective: the main objective of this study is to describe the co-infection Pulmonary Tuberculosis and Severe COVID-19 in pregnant young Woman at the University Hospital of Kinshasa. Method: The report case is of a pregnant woman aged 19 (Pare 2, Gesture 2, Abortion 0) with no known significant medical history, at 32 weeks of gestation based last menstrual period She has benefited from clinic examination, biological examinations (Ziehl’s on sputum), a chest CT scan and a morphological ultrasound. Result: On admission, COVID-19 was the only working diagnosis. However, the persistent coughing prompted clinicians to request a Ziehl-Neelsen staining of sputum that revealed the diagnosis of pulmonary TB. The reverse-transcription polymerase chain reaction (RT-PCR)-confirmed COVID-19 infection and HIV serology negative. A contrast-enhanced chest computed tomography (CT) showed airspace disease involving the right upper lobar, right medial basal segment and left upper lobe in the background of diffuse micro-nodular opacities favored to represent military pulmonary tuberculosis. There were associated cystic bronchiectasis in bilateral upper lobe and bilateral small amount of pleural effusion. Aforementioned findings were favored to represent a secondary or reactivation tuberculosis. The obstetrical ultrasound showed a single live intrauterine pregnancy in breech presentation, estimated at 34 weeks 3 days of gestation without usual features including detectable congenital malformation. Conclusion: The outcome of a pregnant woman with simultaneous COVID-19 and pulmonary tuberculosis is improved when the diagnosis is made early and management is promptly initiated. This attitude also improves the fetal prognosis. In the context of the COVID-19, the association of COVID-19 and pulmonary tuberculosis, especially in immunocompromised patients should be considered.

Published in International Journal of Medical Imaging (Volume 9, Issue 3)
DOI 10.11648/j.ijmi.20210903.13
Page(s) 149-154
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Pulmonary Tuberculosis, COVID-19, Pregnancy, Immunocompromised, Sub-Saharan Africa

References
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Cite This Article
  • APA Style

    Frederick Tshibasu Tshienda, Tresor Mputsu, Ben Bepouka Izizag, Cynthia Minouche Bukumba, Angele Mbongo Tansia, et al. (2021). Co-infection Pulmonary Tuberculosis and Severe COVID-19 in a Pregnant Woman at the University Hospital of Kinshasa: A Case Report. International Journal of Medical Imaging, 9(3), 149-154. https://doi.org/10.11648/j.ijmi.20210903.13

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    ACS Style

    Frederick Tshibasu Tshienda; Tresor Mputsu; Ben Bepouka Izizag; Cynthia Minouche Bukumba; Angele Mbongo Tansia, et al. Co-infection Pulmonary Tuberculosis and Severe COVID-19 in a Pregnant Woman at the University Hospital of Kinshasa: A Case Report. Int. J. Med. Imaging 2021, 9(3), 149-154. doi: 10.11648/j.ijmi.20210903.13

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    AMA Style

    Frederick Tshibasu Tshienda, Tresor Mputsu, Ben Bepouka Izizag, Cynthia Minouche Bukumba, Angele Mbongo Tansia, et al. Co-infection Pulmonary Tuberculosis and Severe COVID-19 in a Pregnant Woman at the University Hospital of Kinshasa: A Case Report. Int J Med Imaging. 2021;9(3):149-154. doi: 10.11648/j.ijmi.20210903.13

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  • @article{10.11648/j.ijmi.20210903.13,
      author = {Frederick Tshibasu Tshienda and Tresor Mputsu and Ben Bepouka Izizag and Cynthia Minouche Bukumba and Angele Mbongo Tansia and Daddy Mata-Mbemba and Madone Mandina Ndona and Joseph Bodi Mabiala and Jean Robert Makulo Risasi and Roger Mbungu Mwimba and Damien Mbanzulu Pita Nsonizau and Jean Marie Kayembe Ntumba and Benjamin Longo Mbenza},
      title = {Co-infection Pulmonary Tuberculosis and Severe COVID-19 in a Pregnant Woman at the University Hospital of Kinshasa: A Case Report},
      journal = {International Journal of Medical Imaging},
      volume = {9},
      number = {3},
      pages = {149-154},
      doi = {10.11648/j.ijmi.20210903.13},
      url = {https://doi.org/10.11648/j.ijmi.20210903.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20210903.13},
      abstract = {Background: To date, world widely, only a couple of papers have reported the association between pulmonary tuberculosis, Coronavirus disease 2019 (COVID-19) and pregnancy, and none of these reports was from sub-Saharan Africa where tuberculosis is endemic. Objective: the main objective of this study is to describe the co-infection Pulmonary Tuberculosis and Severe COVID-19 in pregnant young Woman at the University Hospital of Kinshasa. Method: The report case is of a pregnant woman aged 19 (Pare 2, Gesture 2, Abortion 0) with no known significant medical history, at 32 weeks of gestation based last menstrual period She has benefited from clinic examination, biological examinations (Ziehl’s on sputum), a chest CT scan and a morphological ultrasound. Result: On admission, COVID-19 was the only working diagnosis. However, the persistent coughing prompted clinicians to request a Ziehl-Neelsen staining of sputum that revealed the diagnosis of pulmonary TB. The reverse-transcription polymerase chain reaction (RT-PCR)-confirmed COVID-19 infection and HIV serology negative. A contrast-enhanced chest computed tomography (CT) showed airspace disease involving the right upper lobar, right medial basal segment and left upper lobe in the background of diffuse micro-nodular opacities favored to represent military pulmonary tuberculosis. There were associated cystic bronchiectasis in bilateral upper lobe and bilateral small amount of pleural effusion. Aforementioned findings were favored to represent a secondary or reactivation tuberculosis. The obstetrical ultrasound showed a single live intrauterine pregnancy in breech presentation, estimated at 34 weeks 3 days of gestation without usual features including detectable congenital malformation. Conclusion: The outcome of a pregnant woman with simultaneous COVID-19 and pulmonary tuberculosis is improved when the diagnosis is made early and management is promptly initiated. This attitude also improves the fetal prognosis. In the context of the COVID-19, the association of COVID-19 and pulmonary tuberculosis, especially in immunocompromised patients should be considered.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Co-infection Pulmonary Tuberculosis and Severe COVID-19 in a Pregnant Woman at the University Hospital of Kinshasa: A Case Report
    AU  - Frederick Tshibasu Tshienda
    AU  - Tresor Mputsu
    AU  - Ben Bepouka Izizag
    AU  - Cynthia Minouche Bukumba
    AU  - Angele Mbongo Tansia
    AU  - Daddy Mata-Mbemba
    AU  - Madone Mandina Ndona
    AU  - Joseph Bodi Mabiala
    AU  - Jean Robert Makulo Risasi
    AU  - Roger Mbungu Mwimba
    AU  - Damien Mbanzulu Pita Nsonizau
    AU  - Jean Marie Kayembe Ntumba
    AU  - Benjamin Longo Mbenza
    Y1  - 2021/08/04
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ijmi.20210903.13
    DO  - 10.11648/j.ijmi.20210903.13
    T2  - International Journal of Medical Imaging
    JF  - International Journal of Medical Imaging
    JO  - International Journal of Medical Imaging
    SP  - 149
    EP  - 154
    PB  - Science Publishing Group
    SN  - 2330-832X
    UR  - https://doi.org/10.11648/j.ijmi.20210903.13
    AB  - Background: To date, world widely, only a couple of papers have reported the association between pulmonary tuberculosis, Coronavirus disease 2019 (COVID-19) and pregnancy, and none of these reports was from sub-Saharan Africa where tuberculosis is endemic. Objective: the main objective of this study is to describe the co-infection Pulmonary Tuberculosis and Severe COVID-19 in pregnant young Woman at the University Hospital of Kinshasa. Method: The report case is of a pregnant woman aged 19 (Pare 2, Gesture 2, Abortion 0) with no known significant medical history, at 32 weeks of gestation based last menstrual period She has benefited from clinic examination, biological examinations (Ziehl’s on sputum), a chest CT scan and a morphological ultrasound. Result: On admission, COVID-19 was the only working diagnosis. However, the persistent coughing prompted clinicians to request a Ziehl-Neelsen staining of sputum that revealed the diagnosis of pulmonary TB. The reverse-transcription polymerase chain reaction (RT-PCR)-confirmed COVID-19 infection and HIV serology negative. A contrast-enhanced chest computed tomography (CT) showed airspace disease involving the right upper lobar, right medial basal segment and left upper lobe in the background of diffuse micro-nodular opacities favored to represent military pulmonary tuberculosis. There were associated cystic bronchiectasis in bilateral upper lobe and bilateral small amount of pleural effusion. Aforementioned findings were favored to represent a secondary or reactivation tuberculosis. The obstetrical ultrasound showed a single live intrauterine pregnancy in breech presentation, estimated at 34 weeks 3 days of gestation without usual features including detectable congenital malformation. Conclusion: The outcome of a pregnant woman with simultaneous COVID-19 and pulmonary tuberculosis is improved when the diagnosis is made early and management is promptly initiated. This attitude also improves the fetal prognosis. In the context of the COVID-19, the association of COVID-19 and pulmonary tuberculosis, especially in immunocompromised patients should be considered.
    VL  - 9
    IS  - 3
    ER  - 

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Author Information
  • Division of Diagnostic Imaging, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

  • Division of Infectious Diseases, Kinkole General Reference Hospital, Ministry of Public Health, Kinshasa, Democratic Republic of Congo

  • Division of Infectious Diseases, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

  • Division of Diagnostic Imaging, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

  • Division of Diagnostic Imaging, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

  • Division of Diagnostic Imaging, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

  • Division of Infectious Diseases, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

  • Department of Paediatric, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

  • Division of Nephrology, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

  • Department of Genecology and Obstetrics, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

  • Department of Genecology and Obstetrics, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

  • Division of Pneumology, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

  • Division of Cardiology, University Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of Congo

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