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Novel Method to Diagnose COVID-19: HNN of CNN and Bi-LSTM Using X-ray Images

Received: 25 January 2021    Accepted: 2 February 2021    Published: 4 March 2021
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Abstract

Coronavirus Disease (COVID-19) has caused a global pandemic and many of COVID-19’s key symptoms are related to the respiratory tract. In fact, the most relevant features correlated to the diagnosis of COVID-19 were found to be breathing problems and dry cough as determined by experimental results, produced when such a dataset was run through the random forest model with feature importance function. Therefore, using chest x-ray images labeled as COVID-19 and normal from kaggle, we developed a novel hybrid deep learning model incorporating CNN (convolutional neural network) and Bi-LSTM (bidirectional long short term memory) to detect symptoms of COVID-19. Our goal was to develop a model with the highest accuracy. As a total number of datasets were not enough to train the model, we augmented the input dataset through the “ImagedataGenerator” function from the Keras. Also, this proposed model ensures high accuracy as experimental results reported its average accuracy, which was tested with various optimizers (Adam, Nadam, Rmsprop, SGD), to be 98.13%. The new model showed the highest average accuracy compared to any other preexisting models (VGG-16, Resnet50, Resent50_v2, Mobilenet, Mobilenet_v2, Xception) also tested during this research. This model could potentially be used as an alternative process to diagnose COVID-19, especially with the number of global cases increasing, along with the need for efficient, quicker testing methods.

Published in International Journal of Medical Imaging (Volume 9, Issue 1)
DOI 10.11648/j.ijmi.20210901.18
Page(s) 79-86
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

COVID-19, Chest X-ray, Hybrid Model, CNN, Bi-LSTM, Optimizers

References
[1] Weekly epidemiological update. (2021, January 05). Retrieved January 09, 2021, from https://www.who.int/publications/m/item/weekly-epidemiological-update---5-january-2021
[2] COVID-19 Mythbusters. (2020, November 03). Retrieved January 09, 2021, from https://www.who.int/emergencies/diseases/novel-coronavirus-2019/advice-for-public/myth-busters
[3] Novel Coronavirus – China. (2020, January 13). Retrieved January 09, 2021, from https://www.who.int/csr/don/12-january-2020-novel-coronavirus-china/en/
[4] Coronavirus disease (COVID-19). (2020, October 12). Retrieved January 09, 2021, from https://www.who.int/emergencies/diseases/novel-coronavirus-2019/question-and-answers-hub/q-a-detail/coronavirus-disease-COVID-19#:~:text=symptoms
[5] Cleverley, J., Piper, J., & Jones, M. (2020, July 16). The role of chest radiography in confirming COVID-19 pneumonia. Retrieved January 09, 2021, from https://www.bmj.com/content/370/bmj.m2426
[6] Chest X-Ray. (n.d.). Retrieved January 09, 2021, from https://www.nhlbi.nih.gov/health-topics/chest-x-ray#:~:text=A%20chest%20X%2Dray%20is,in%20and%20around%20your%20chest.&text=This%20test%20can%20help%20diagnose,lung%20tissue%20scarring%2C%20called%20fibrosis.
[7] Yan, T., Wong, P. K., Ren, H., Wang, H., Wang, J., & Li, Y. (2020). Automatic distinction between COVID-19 and common pneumonia using multi-scale convolutional neural network on chest CT scans. Chaos, Solitons & Fractals, 140. [doi: 10.1016/j.chaos.2020.110153].
[8] Altan, A., & Karasu, S. (2020). Recognition of COVID-19 disease from X-ray images by hybrid model consisting of 2D curvelet transform, chaotic salp swarm algorithm and deep learning technique. Chaos, Solitons & Fractals, 140. [doi: 10.1016/j.chaos.2020.110071].
[9] Hassantabar, S., Ahmadi, M., & Sharifi, A. (2020). Diagnosis and detection of infected tissue of COVID-19 patients based on lung x-ray image using convolutional neural network approaches. Chaos, Solitons & Fractals, 140. [doi: 10.1016/j.chaos.2020.110170].
[10] Brunese, L., Mercaldo, F., Reginelli, A., & Santone, A. (2020). Explainable Deep Learning for Pulmonary Disease and Coronavirus COVID-19 Detection from X-rays. Computer Methods and Programs in Biomedicine, 196. [doi: 10.1016/j.cmpb.2020.105608].
[11] Alakus, T. B., & Turkoglu, I. (2020). Comparison of deep learning approaches to predict COVID-19 infection. Chaos, Solitons & Fractals, 140. [doi: 10.1016/j.chaos.2020.110120].
[12] Svetnik, V. et al. (2003). Random Forest:  A Classification and Regression Tool for Compound Classification and QSAR Modeling. Journal of chemical information and computer sciences, 43 (6), s. 1947–1958. [doi: 10.1021/ci034160g].
[13] Li, Q. et al. (2014). Medical image classification with convolutional neural network. [doi: 10.1109/icarcv.2014.7064414].
[14] Pal, M. (2005). Random forest classifier for remote sensing classification. International Journal of Remote Sensing, 26 (1), 217-222. [doi: 10.1080/01431160412331269698].
[15] Baskin, I. I., Marcou, G., Horvath, D., & Varnek, A. (2017). Bagging and Boosting of Classification Models. Tutorials in Chemoinformatics, 241-247. [doi: 10.1002/9781119161110.ch15].
[16] Hochreiter, S., & Schmidhuber, J. (1997). Long Short-Term Memory. Neural Computation, 9 (8), 1735-1780. [doi: 10.1162/neco.1997.9.8.1735].
[17] Graves, A., & Schmidhuber, J. (2005). Framewise phoneme classification with bidirectional LSTM and other neural network architectures. Neural Networks, 18 (5-6), 602-610. [doi: 10.1016/j.neunet.2005.06.042].
[18] Barrell, A. (2020, September 08). Coronavirus (COVID-19) test results: How long do they take? Retrieved January 09, 2021, from https://www.medicalnewstoday.com/articles/coronavirus-COVID-19-test-results-how-long
[19] X-Rays (Medical Test) - Purpose, Procedure, Risks, Results. (2020, July 07). Retrieved January 09, 2021, from https://www.webmd.com/a-to-z-guides/what-is-x-ray#1
Cite This Article
  • APA Style

    Hannah Kim, Gina Kim. (2021). Novel Method to Diagnose COVID-19: HNN of CNN and Bi-LSTM Using X-ray Images. International Journal of Medical Imaging, 9(1), 79-86. https://doi.org/10.11648/j.ijmi.20210901.18

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    ACS Style

    Hannah Kim; Gina Kim. Novel Method to Diagnose COVID-19: HNN of CNN and Bi-LSTM Using X-ray Images. Int. J. Med. Imaging 2021, 9(1), 79-86. doi: 10.11648/j.ijmi.20210901.18

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    AMA Style

    Hannah Kim, Gina Kim. Novel Method to Diagnose COVID-19: HNN of CNN and Bi-LSTM Using X-ray Images. Int J Med Imaging. 2021;9(1):79-86. doi: 10.11648/j.ijmi.20210901.18

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  • @article{10.11648/j.ijmi.20210901.18,
      author = {Hannah Kim and Gina Kim},
      title = {Novel Method to Diagnose COVID-19: HNN of CNN and Bi-LSTM Using X-ray Images},
      journal = {International Journal of Medical Imaging},
      volume = {9},
      number = {1},
      pages = {79-86},
      doi = {10.11648/j.ijmi.20210901.18},
      url = {https://doi.org/10.11648/j.ijmi.20210901.18},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20210901.18},
      abstract = {Coronavirus Disease (COVID-19) has caused a global pandemic and many of COVID-19’s key symptoms are related to the respiratory tract. In fact, the most relevant features correlated to the diagnosis of COVID-19 were found to be breathing problems and dry cough as determined by experimental results, produced when such a dataset was run through the random forest model with feature importance function. Therefore, using chest x-ray images labeled as COVID-19 and normal from kaggle, we developed a novel hybrid deep learning model incorporating CNN (convolutional neural network) and Bi-LSTM (bidirectional long short term memory) to detect symptoms of COVID-19. Our goal was to develop a model with the highest accuracy. As a total number of datasets were not enough to train the model, we augmented the input dataset through the “ImagedataGenerator” function from the Keras. Also, this proposed model ensures high accuracy as experimental results reported its average accuracy, which was tested with various optimizers (Adam, Nadam, Rmsprop, SGD), to be 98.13%. The new model showed the highest average accuracy compared to any other preexisting models (VGG-16, Resnet50, Resent50_v2, Mobilenet, Mobilenet_v2, Xception) also tested during this research. This model could potentially be used as an alternative process to diagnose COVID-19, especially with the number of global cases increasing, along with the need for efficient, quicker testing methods.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Novel Method to Diagnose COVID-19: HNN of CNN and Bi-LSTM Using X-ray Images
    AU  - Hannah Kim
    AU  - Gina Kim
    Y1  - 2021/03/04
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ijmi.20210901.18
    DO  - 10.11648/j.ijmi.20210901.18
    T2  - International Journal of Medical Imaging
    JF  - International Journal of Medical Imaging
    JO  - International Journal of Medical Imaging
    SP  - 79
    EP  - 86
    PB  - Science Publishing Group
    SN  - 2330-832X
    UR  - https://doi.org/10.11648/j.ijmi.20210901.18
    AB  - Coronavirus Disease (COVID-19) has caused a global pandemic and many of COVID-19’s key symptoms are related to the respiratory tract. In fact, the most relevant features correlated to the diagnosis of COVID-19 were found to be breathing problems and dry cough as determined by experimental results, produced when such a dataset was run through the random forest model with feature importance function. Therefore, using chest x-ray images labeled as COVID-19 and normal from kaggle, we developed a novel hybrid deep learning model incorporating CNN (convolutional neural network) and Bi-LSTM (bidirectional long short term memory) to detect symptoms of COVID-19. Our goal was to develop a model with the highest accuracy. As a total number of datasets were not enough to train the model, we augmented the input dataset through the “ImagedataGenerator” function from the Keras. Also, this proposed model ensures high accuracy as experimental results reported its average accuracy, which was tested with various optimizers (Adam, Nadam, Rmsprop, SGD), to be 98.13%. The new model showed the highest average accuracy compared to any other preexisting models (VGG-16, Resnet50, Resent50_v2, Mobilenet, Mobilenet_v2, Xception) also tested during this research. This model could potentially be used as an alternative process to diagnose COVID-19, especially with the number of global cases increasing, along with the need for efficient, quicker testing methods.
    VL  - 9
    IS  - 1
    ER  - 

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Author Information
  • Yongsan International School of Seoul, Seoul, Republic of Korea

  • Yongsan International School of Seoul, Seoul, Republic of Korea

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