Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors

Sara Essam Hasby; Al-Shaimaa Zakaria Elshahawy; Mohamed Amin Mohamed; Ali Ibraheem Seif Eldean; Mohammed Fathy Dawoud

doi:doi:10.11648/j.ijmi.20210901.12

| Peer-Reviewed

Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors

Sara Essam Hasby, Al-Shaimaa Zakaria Elshahawy, Mohamed Amin Mohamed, Ali Ibraheem Seif Eldean, Mohammed Fathy Dawoud

Published in International Journal of Medical Imaging (Volume 9, Issue 1)

Received: 20 December 2020 Accepted: 30 December 2020 Published: 12 January 2021

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Diffusion tensor imaging is a non-invasive magnetic resonance imaging technique that describe the orientation and location of white matter tracts in vivo, it guides the surgeon regarding the relationship of the intra-axial tumor to adjacent white matter tracts in different planes. Routine pre-surgical FMRI allows for assessment of the relationship between brain tumor and motor cortex to facilitate function-preserving surgery and reduce postoperative morbidity. The purpose of this study is to evaluate role of diffusion tensor magnetic resonance imaging, fiber tractography and motor functional MRI in assessment of white matter tracts affected by the tumor, and to utilize this information in guiding surgeons. Fifty patients with different types of brain tumors were enrolled in this study. Fiber tracts involvement were classified into four categories (edema, displacement, infiltration and disruption), comparison between benign and malignant tumors groups as regards to the patterns of fiber tracts involvement were done. The prevalence of edema and displacement was higher among the benign group while prevalence of infiltration and disruption was higher among the malignant group. Localization of the primary motor hand area with functional MRI was done, The relation of it to the tumor was measured. Treatment plans before and after DTI & functional MR imaging differed in 35 patients as regard to surgical approach and in 17 patients as regard to modification of extent of resection with significant relation. Diffusion tensor imaging DTI represents recent important progress in the field of diagnostic imaging. It is the only technique that is able to visualize in vivo white-matter tracts so that it is of great help in pre-operative neurosurgical planning.

Published in	International Journal of Medical Imaging (Volume 9, Issue 1)
DOI	10.11648/j.ijmi.20210901.12
Page(s)	16-28
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Diffusion Tensor Imaging, Fiber Tractography, Motor Functional MRI, Brain Tumors

References

[1]	Commowick O, Fillard P, Clatz O. Detection of DTI white matter abnormalities in multiple sclerosis patients. Warfield Med. Image Comput. Assist. Interv. 2008; 11 (Pt 1): 975–982.
[2]	Yu HJ, Christodoulou C, Bhise V, et al. Multiple white matter tract abnormalities underlie cognitive impairment in RRMS. Neuroimage. 2012; 59: 3713–3722.
[3]	Mori S, van Zijl PC. Fiber tracking: principles and strategies-a technical review. NMR. Biomed. 2002; 15: 468–480.
[4]	Farmanfarma KK, Mohammadian M, Shahabinia Z, et al. Brain cancer in the world: an epidemiological review. world cancer Res J. 2019; 5 (4): 1–5. 94.
[5]	Sun T, Plutynski A, Ward S, et al. An integrative view on sex differences in brain tumors. Cell Mol Life Sci. 2015; 72 (17): 3323–3342.
[6]	Afanasjeva, B, Afanasjevas, D; Jaškevičienė, V; et al. Clinical symptoms of benign brain tumours. Neurol Semin. 2018; 22 (3): 269–271.
[7]	Ozawa M, Brennan PM, Zienius K, et al. The usefulness of symptoms alone or combined for general practitioners in considering the diagnosis of a brain tumour: A case-control study using the clinical practice research database (CPRD) (2000-2014). BMJ Open. 2019; 9 (8). https://doi.org/10.1136/bmjopen-2019-029686.
[8]	Lapointe S, Perry A and Butowski NA. Primary brain tumours in adults. Lancet. 2018; 392 (10145): 432–446.
[9]	Mamiya T, Shimato S, Nishizawa T, et al. Malignant Glioma in the Cerebellum Presenting as Multiple Small Lesions. Case Rep Oncol Med. 2019; 2019: 1–5.
[10]	Field AS, Alexander AL, Wu YC, et al. Diffusion tensor eigenvector directional color imaging patterns in the evaluation of cerebral white matter tracts altered by tumor. J Magn Reson Imaging. 2004; 20 (4): 555–562.
[11]	G. Karthika, Anand. R and Vayshak K. V. SS. A retrospective study on role of DTI in brain tumours. Int J Contemp Med Surg Radiol. 2019; 4 (4): 14–18.
[12]	Panesar SS, Abhinav K, Yeh FC, et al. Tractography for Surgical Neuro-Oncology Planning: Towards a Gold Standard. Neurotherapeutics. 2019; 16 (1): 36–51.
[13]	Itagiba VGA, Borges R, da Cruz LCH, et al. Use of diffusion tensor magnetic resonance imaging in the assessment of patterns of white matter involvement in patients with brain tumors: is it useful in the differential diagnosis?. Radiol Bras. 2010;43 (6): 362–368.
[14]	Dubey A, Kataria R and Sinha V. Role of diffusion tensor imaging in brain tumor surgery. Asian J Neurosurg. 2018; 13 (2): 302.
[15]	Beppu T, Inoue T, Shibata Y, et al Fractional anisotropy value by diffusion tensor magnetic resonance imaging as a predictor of cell density and proliferation activity of glioblastomas. Surg Neurol. 2005; 63 (1): 56–61.
[16]	Kallenberg K, Goldmann T, Menke J, et al. Glioma infiltration of the corpus callosum: Early signs detected by DTI. J Neurooncol. 2013; 112 (2): 217–222.
[17]	Romano A, D’Andrea G, Minniti G, et al. Pre-surgical planning and MR-tractography utility in brain tumour resection. Ekartur Radiol. 2009; 19 (12): 2798–808.
[18]	Cao ZK, Lv JP, Wei X, et al. Appliance of preoperative diffusion tensor imaging and fiber tractography in patients with brainstem lesions. Neurol India. 2010; 58 (6): 886–890.
[19]	Castellano A, Bello L, Michelozzi C, et al. Role of diffusion tensor magnetic resonance tractography in predicting the extent of resection in glioma surgery. Neuro Oncol. 2012; 14 (2): 192–202.
[20]	Krings T, Reinges MHT, Erberich S, et al. Functional MRI for presurgical planning: Problems, artefacts, and solution strategies. J Neurol Neurosurg Psychiatry. 2001;70 (6): 749–760.
[21]	Hoeller M, Krings T, Reinges MHT, et al. Movement artefacts and MR BOLD signal increase during different paradigms for mapping the sensorimotor cortex. Acta Neurochir (Wien). 2002; 144 (3): 279–284.

Cite This Article

Plain Text BibTeX RIS

APA Style

Sara Essam Hasby, Al-Shaimaa Zakaria Elshahawy, Mohamed Amin Mohamed, Ali Ibraheem Seif Eldean, Mohammed Fathy Dawoud. (2021). Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors. International Journal of Medical Imaging, 9(1), 16-28. https://doi.org/10.11648/j.ijmi.20210901.12

Copy | Download

ACS Style

Sara Essam Hasby; Al-Shaimaa Zakaria Elshahawy; Mohamed Amin Mohamed; Ali Ibraheem Seif Eldean; Mohammed Fathy Dawoud. Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors. Int. J. Med. Imaging 2021, 9(1), 16-28. doi: 10.11648/j.ijmi.20210901.12

Copy | Download

AMA Style

Sara Essam Hasby, Al-Shaimaa Zakaria Elshahawy, Mohamed Amin Mohamed, Ali Ibraheem Seif Eldean, Mohammed Fathy Dawoud. Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors. Int J Med Imaging. 2021;9(1):16-28. doi: 10.11648/j.ijmi.20210901.12

Copy | Download

@article{10.11648/j.ijmi.20210901.12,
  author = {Sara Essam Hasby and Al-Shaimaa Zakaria Elshahawy and Mohamed Amin Mohamed and Ali Ibraheem Seif Eldean and Mohammed Fathy Dawoud},
  title = {Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors},
  journal = {International Journal of Medical Imaging},
  volume = {9},
  number = {1},
  pages = {16-28},
  doi = {10.11648/j.ijmi.20210901.12},
  url = {https://doi.org/10.11648/j.ijmi.20210901.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20210901.12},
  abstract = {Diffusion tensor imaging is a non-invasive magnetic resonance imaging technique that describe the orientation and location of white matter tracts in vivo, it guides the surgeon regarding the relationship of the intra-axial tumor to adjacent white matter tracts in different planes. Routine pre-surgical FMRI allows for assessment of the relationship between brain tumor and motor cortex to facilitate function-preserving surgery and reduce postoperative morbidity. The purpose of this study is to evaluate role of diffusion tensor magnetic resonance imaging, fiber tractography and motor functional MRI in assessment of white matter tracts affected by the tumor, and to utilize this information in guiding surgeons. Fifty patients with different types of brain tumors were enrolled in this study. Fiber tracts involvement were classified into four categories (edema, displacement, infiltration and disruption), comparison between benign and malignant tumors groups as regards to the patterns of fiber tracts involvement were done. The prevalence of edema and displacement was higher among the benign group while prevalence of infiltration and disruption was higher among the malignant group. Localization of the primary motor hand area with functional MRI was done, The relation of it to the tumor was measured. Treatment plans before and after DTI & functional MR imaging differed in 35 patients as regard to surgical approach and in 17 patients as regard to modification of extent of resection with significant relation. Diffusion tensor imaging DTI represents recent important progress in the field of diagnostic imaging. It is the only technique that is able to visualize in vivo white-matter tracts so that it is of great help in pre-operative neurosurgical planning.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors
AU  - Sara Essam Hasby
AU  - Al-Shaimaa Zakaria Elshahawy
AU  - Mohamed Amin Mohamed
AU  - Ali Ibraheem Seif Eldean
AU  - Mohammed Fathy Dawoud
Y1  - 2021/01/12
PY  - 2021
N1  - https://doi.org/10.11648/j.ijmi.20210901.12
DO  - 10.11648/j.ijmi.20210901.12
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 16
EP  - 28
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20210901.12
AB  - Diffusion tensor imaging is a non-invasive magnetic resonance imaging technique that describe the orientation and location of white matter tracts in vivo, it guides the surgeon regarding the relationship of the intra-axial tumor to adjacent white matter tracts in different planes. Routine pre-surgical FMRI allows for assessment of the relationship between brain tumor and motor cortex to facilitate function-preserving surgery and reduce postoperative morbidity. The purpose of this study is to evaluate role of diffusion tensor magnetic resonance imaging, fiber tractography and motor functional MRI in assessment of white matter tracts affected by the tumor, and to utilize this information in guiding surgeons. Fifty patients with different types of brain tumors were enrolled in this study. Fiber tracts involvement were classified into four categories (edema, displacement, infiltration and disruption), comparison between benign and malignant tumors groups as regards to the patterns of fiber tracts involvement were done. The prevalence of edema and displacement was higher among the benign group while prevalence of infiltration and disruption was higher among the malignant group. Localization of the primary motor hand area with functional MRI was done, The relation of it to the tumor was measured. Treatment plans before and after DTI & functional MR imaging differed in 35 patients as regard to surgical approach and in 17 patients as regard to modification of extent of resection with significant relation. Diffusion tensor imaging DTI represents recent important progress in the field of diagnostic imaging. It is the only technique that is able to visualize in vivo white-matter tracts so that it is of great help in pre-operative neurosurgical planning.
VL  - 9
IS  - 1
ER  -

Copy | Download

Author Information

Sara Essam Hasby

Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt
Al-Shaimaa Zakaria Elshahawy

Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt
Mohamed Amin Mohamed

Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt
Ali Ibraheem Seif Eldean

Department of Neurosurgery, Faculty of Medicine, Tanta University, Tanta, Egypt
Mohammed Fathy Dawoud

Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Sara Essam Hasby, Al-Shaimaa Zakaria Elshahawy, Mohamed Amin Mohamed, Ali Ibraheem Seif Eldean, Mohammed Fathy Dawoud. (2021). Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors. International Journal of Medical Imaging, 9(1), 16-28. https://doi.org/10.11648/j.ijmi.20210901.12

Copy | Download

ACS Style

Sara Essam Hasby; Al-Shaimaa Zakaria Elshahawy; Mohamed Amin Mohamed; Ali Ibraheem Seif Eldean; Mohammed Fathy Dawoud. Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors. Int. J. Med. Imaging 2021, 9(1), 16-28. doi: 10.11648/j.ijmi.20210901.12

Copy | Download

AMA Style

Sara Essam Hasby, Al-Shaimaa Zakaria Elshahawy, Mohamed Amin Mohamed, Ali Ibraheem Seif Eldean, Mohammed Fathy Dawoud. Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors. Int J Med Imaging. 2021;9(1):16-28. doi: 10.11648/j.ijmi.20210901.12

Copy | Download

@article{10.11648/j.ijmi.20210901.12,
  author = {Sara Essam Hasby and Al-Shaimaa Zakaria Elshahawy and Mohamed Amin Mohamed and Ali Ibraheem Seif Eldean and Mohammed Fathy Dawoud},
  title = {Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors},
  journal = {International Journal of Medical Imaging},
  volume = {9},
  number = {1},
  pages = {16-28},
  doi = {10.11648/j.ijmi.20210901.12},
  url = {https://doi.org/10.11648/j.ijmi.20210901.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20210901.12},
  abstract = {Diffusion tensor imaging is a non-invasive magnetic resonance imaging technique that describe the orientation and location of white matter tracts in vivo, it guides the surgeon regarding the relationship of the intra-axial tumor to adjacent white matter tracts in different planes. Routine pre-surgical FMRI allows for assessment of the relationship between brain tumor and motor cortex to facilitate function-preserving surgery and reduce postoperative morbidity. The purpose of this study is to evaluate role of diffusion tensor magnetic resonance imaging, fiber tractography and motor functional MRI in assessment of white matter tracts affected by the tumor, and to utilize this information in guiding surgeons. Fifty patients with different types of brain tumors were enrolled in this study. Fiber tracts involvement were classified into four categories (edema, displacement, infiltration and disruption), comparison between benign and malignant tumors groups as regards to the patterns of fiber tracts involvement were done. The prevalence of edema and displacement was higher among the benign group while prevalence of infiltration and disruption was higher among the malignant group. Localization of the primary motor hand area with functional MRI was done, The relation of it to the tumor was measured. Treatment plans before and after DTI & functional MR imaging differed in 35 patients as regard to surgical approach and in 17 patients as regard to modification of extent of resection with significant relation. Diffusion tensor imaging DTI represents recent important progress in the field of diagnostic imaging. It is the only technique that is able to visualize in vivo white-matter tracts so that it is of great help in pre-operative neurosurgical planning.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors
AU  - Sara Essam Hasby
AU  - Al-Shaimaa Zakaria Elshahawy
AU  - Mohamed Amin Mohamed
AU  - Ali Ibraheem Seif Eldean
AU  - Mohammed Fathy Dawoud
Y1  - 2021/01/12
PY  - 2021
N1  - https://doi.org/10.11648/j.ijmi.20210901.12
DO  - 10.11648/j.ijmi.20210901.12
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 16
EP  - 28
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20210901.12
AB  - Diffusion tensor imaging is a non-invasive magnetic resonance imaging technique that describe the orientation and location of white matter tracts in vivo, it guides the surgeon regarding the relationship of the intra-axial tumor to adjacent white matter tracts in different planes. Routine pre-surgical FMRI allows for assessment of the relationship between brain tumor and motor cortex to facilitate function-preserving surgery and reduce postoperative morbidity. The purpose of this study is to evaluate role of diffusion tensor magnetic resonance imaging, fiber tractography and motor functional MRI in assessment of white matter tracts affected by the tumor, and to utilize this information in guiding surgeons. Fifty patients with different types of brain tumors were enrolled in this study. Fiber tracts involvement were classified into four categories (edema, displacement, infiltration and disruption), comparison between benign and malignant tumors groups as regards to the patterns of fiber tracts involvement were done. The prevalence of edema and displacement was higher among the benign group while prevalence of infiltration and disruption was higher among the malignant group. Localization of the primary motor hand area with functional MRI was done, The relation of it to the tumor was measured. Treatment plans before and after DTI & functional MR imaging differed in 35 patients as regard to surgical approach and in 17 patients as regard to modification of extent of resection with significant relation. Diffusion tensor imaging DTI represents recent important progress in the field of diagnostic imaging. It is the only technique that is able to visualize in vivo white-matter tracts so that it is of great help in pre-operative neurosurgical planning.
VL  - 9
IS  - 1
ER  -

Copy | Download