Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis

Asmaa Hamdy Mohamed Dkhail; Samah Ahmed Ibrahim Radwan; Hossam Mostafa Gad; Hanan Mohamed Saleh El-Ahwal

doi:doi:10.11648/j.ijmi.20200804.17

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Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis

Asmaa Hamdy Mohamed Dkhail, Samah Ahmed Ibrahim Radwan, Hossam Mostafa Gad, Hanan Mohamed Saleh El-Ahwal

Published in International Journal of Medical Imaging (Volume 8, Issue 4)

Received: 23 November 2020 Accepted: 4 December 2020 Published: 11 December 2020

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Abstract

Imaging of children who had symptoms and signs of pyelonephritis is aimed to diagnosis of renal injury and identification of risk factors for pyelonephritis that might be uncovered during imaging includes vesico- ureteric reflux (VUR). The purpose of this study was to determine the role of static renal scintigraphy in diagnosis of pediatric renal pyelonephritis and the value of single photon emission computed tomography (SPECT) in diagnosis. This study was carried out on 50 patients in Radiology Department at Mansoura Urology and Nephrology center and Radiology department at Tanta university hospitals. High grade vesicoureteric reflux "VUR" (grade IV & V) was detected in 70% of the cases. 42.8% of the cases had vesicoureteric reflux in both kidneys, 42.8% of the cases had VUR only on the left side and 14.2% of the cases had VUR on the right side. A statistical significance was found between grades of pyelonephritis and grades of vescio-ureteric reflux, so there was a strong association between high grade VUR and renal pyelonephritis. It was found that no significant difference was found as regard to the number of abnormal segments detected by static renal scintigraphy and SPECT imaging. Static renal scintigraphy is considered the gold standard for diagnosis of children with pyelonephritis and detection the risk of renal scarring due to recurrent infection. SPECT offers no statistically significant diagnostic advantage over static images for detection of cortical defects.

Published in	International Journal of Medical Imaging (Volume 8, Issue 4)
DOI	10.11648/j.ijmi.20200804.17
Page(s)	106-113
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Static Renal Scintigraphy, Pediatric Renal Pyelonephritis, Vesico-ureteric Reflux

References

[1]	Spasojević-Dimitrijeva B, Živkovi M, Stanković A, et al: The IL-6 −174G/C polymorphism and renal scarring in children with first acute pyelonephritis. Pediatric Nephrology. 2010; 25: 2099–2106.
[2]	Conway PH, Cnaan A, Zaoutis T, et al: Recurrent urinary tract infections in children: risk factors and association with prophylactic antimicrobials. JAMA. 2007; 298: 179-86.
[3]	Coulthard MG. Is reflux nephropathy preventable, and will the NICE childhood UTI guidelines help? Achieves of Diseases in Childhood. 2008; 93: 196-209.
[4]	Nikolaidis P, Dogra VS, Goldfarb S, et al: ACR Appropriateness Criteria: Acute Pyelonephritis. Journal of the American College of Radiology. 2018; 15: 5232-5239.
[5]	Mandell GA, Eggli DF, Gilday DL, et al: Society of Nuclear Medicine procedure guideline for renal cortical scintigraphy in children. SNM Procedure Guidelines Manual 2003; 24: 195-198.
[6]	Sheehy N, Tetrault TA, Zurakowski D, et al: Pediatric 99mTc-DMSA SPECT performed by using iterative reconstruction with isotropic resolution recovery: improved image quality and reduced radiopharmaceutical activity. Radiology. 2009; 251: 511-516.
[7]	Tsalkidis A, Gardikis S, Kambouri K, et al: (99m) Tc-DMSA scintigraphy diagnosing crossed renal ectopia with fusion in a three years old boy. Hell Journal of Nuclear Medicine. 2011; 14: 300-303.
[8]	Snodgrass WT, Shah A, Yang M, et al: Prevalence and risk factors for renal scars in children with febrile UTI and/or VUR: A cross-sectional observational study of 565 consecutive patients. Journal of Pediatric Urology. 2013; 9: 856-866.
[9]	Ross I, Jun Ahn H, Roelof B, et al: Sonographic assessment of the effect of vesicoureteral reflux and urinary tract infections on growth of the pediatric solitary kidney. Journal of Pediatric Urology. 2015; 11: 145. e2-145. e6.
[10]	Kandur Y., Salan A., Tuten F.: Correlation of ultrasonographical findings of hydronephrosis/ atrophy with 99m technetium dimercaptosuccinic acid in childhood: A single center experience from Turkey. Urology annuals. 2018; 10: 296-301.
[11]	Tseng M, Lin W, Lo W, et al: Does a normal DMSA obviate the performance of voiding cystourethrography in evaluation of young children after their first urinary tract infection?. The Journal of Pediatrics. 2007; 150: 96-109.
[12]	Cerwinka WH, Grattan-Smith JD, Jones RA, et al: Comparison of magnetic resonance urography to dimercaptosuccinic acid scan for the identification of renal parenchyma defects in children with vesicoureteral reflux. Journal of Pediatric Urology. 2014; 10: 344-351.
[13]	Zhang X, Xu H, Zhou L, et al: Accuracy of early DMSA scan for VUR in young children with febrile UTI. Pediatrics. 2014; 133: e30-e38.
[14]	Wein AJ, Kavoussi LR, Partin AW, et al: Pediatric urological imaging. In Martin AD., Pohl HG. Campbell-Walsh urology 11^th edition. Elservier. 2016; 126: 2909-2925.
[15]	Kim JE, Kim JS, Han JB, et al: Clinical usefulness of ^99mTc-DMSA renal SPECT using high sensitivity-all-purpose collimator for pediatric patients. JKCA. 2014; 16.220-231.

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APA Style

Asmaa Hamdy Mohamed Dkhail, Samah Ahmed Ibrahim Radwan, Hossam Mostafa Gad, Hanan Mohamed Saleh El-Ahwal. (2020). Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis. International Journal of Medical Imaging, 8(4), 106-113. https://doi.org/10.11648/j.ijmi.20200804.17

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ACS Style

Asmaa Hamdy Mohamed Dkhail; Samah Ahmed Ibrahim Radwan; Hossam Mostafa Gad; Hanan Mohamed Saleh El-Ahwal. Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis. Int. J. Med. Imaging 2020, 8(4), 106-113. doi: 10.11648/j.ijmi.20200804.17

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AMA Style

Asmaa Hamdy Mohamed Dkhail, Samah Ahmed Ibrahim Radwan, Hossam Mostafa Gad, Hanan Mohamed Saleh El-Ahwal. Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis. Int J Med Imaging. 2020;8(4):106-113. doi: 10.11648/j.ijmi.20200804.17

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@article{10.11648/j.ijmi.20200804.17,
  author = {Asmaa Hamdy Mohamed Dkhail and Samah Ahmed Ibrahim Radwan and Hossam Mostafa Gad and Hanan Mohamed Saleh El-Ahwal},
  title = {Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis},
  journal = {International Journal of Medical Imaging},
  volume = {8},
  number = {4},
  pages = {106-113},
  doi = {10.11648/j.ijmi.20200804.17},
  url = {https://doi.org/10.11648/j.ijmi.20200804.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20200804.17},
  abstract = {Imaging of children who had symptoms and signs of pyelonephritis is aimed to diagnosis of renal injury and identification of risk factors for pyelonephritis that might be uncovered during imaging includes vesico- ureteric reflux (VUR). The purpose of this study was to determine the role of static renal scintigraphy in diagnosis of pediatric renal pyelonephritis and the value of single photon emission computed tomography (SPECT) in diagnosis. This study was carried out on 50 patients in Radiology Department at Mansoura Urology and Nephrology center and Radiology department at Tanta university hospitals. High grade vesicoureteric reflux "VUR" (grade IV & V) was detected in 70% of the cases. 42.8% of the cases had vesicoureteric reflux in both kidneys, 42.8% of the cases had VUR only on the left side and 14.2% of the cases had VUR on the right side. A statistical significance was found between grades of pyelonephritis and grades of vescio-ureteric reflux, so there was a strong association between high grade VUR and renal pyelonephritis. It was found that no significant difference was found as regard to the number of abnormal segments detected by static renal scintigraphy and SPECT imaging. Static renal scintigraphy is considered the gold standard for diagnosis of children with pyelonephritis and detection the risk of renal scarring due to recurrent infection. SPECT offers no statistically significant diagnostic advantage over static images for detection of cortical defects.},
 year = {2020}
}

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TY  - JOUR
T1  - Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis
AU  - Asmaa Hamdy Mohamed Dkhail
AU  - Samah Ahmed Ibrahim Radwan
AU  - Hossam Mostafa Gad
AU  - Hanan Mohamed Saleh El-Ahwal
Y1  - 2020/12/11
PY  - 2020
N1  - https://doi.org/10.11648/j.ijmi.20200804.17
DO  - 10.11648/j.ijmi.20200804.17
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 106
EP  - 113
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20200804.17
AB  - Imaging of children who had symptoms and signs of pyelonephritis is aimed to diagnosis of renal injury and identification of risk factors for pyelonephritis that might be uncovered during imaging includes vesico- ureteric reflux (VUR). The purpose of this study was to determine the role of static renal scintigraphy in diagnosis of pediatric renal pyelonephritis and the value of single photon emission computed tomography (SPECT) in diagnosis. This study was carried out on 50 patients in Radiology Department at Mansoura Urology and Nephrology center and Radiology department at Tanta university hospitals. High grade vesicoureteric reflux "VUR" (grade IV & V) was detected in 70% of the cases. 42.8% of the cases had vesicoureteric reflux in both kidneys, 42.8% of the cases had VUR only on the left side and 14.2% of the cases had VUR on the right side. A statistical significance was found between grades of pyelonephritis and grades of vescio-ureteric reflux, so there was a strong association between high grade VUR and renal pyelonephritis. It was found that no significant difference was found as regard to the number of abnormal segments detected by static renal scintigraphy and SPECT imaging. Static renal scintigraphy is considered the gold standard for diagnosis of children with pyelonephritis and detection the risk of renal scarring due to recurrent infection. SPECT offers no statistically significant diagnostic advantage over static images for detection of cortical defects.
VL  - 8
IS  - 4
ER  -

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Author Information

Asmaa Hamdy Mohamed Dkhail

Radiodiagnosis Department, Faculty of Medicine, Tanta University, Tanta, Egypt
Samah Ahmed Ibrahim Radwan

Radiodiagnosis Department, Faculty of Medicine, Tanta University, Tanta, Egypt
Hossam Mostafa Gad

Radiology Department, Mansoura Urology and Nephrology Center, Mansoura University, Mansoura, Egypt
Hanan Mohamed Saleh El-Ahwal

Radiodiagnosis Department, Faculty of Medicine, Tanta University, Tanta, Egypt

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APA Style

Asmaa Hamdy Mohamed Dkhail, Samah Ahmed Ibrahim Radwan, Hossam Mostafa Gad, Hanan Mohamed Saleh El-Ahwal. (2020). Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis. International Journal of Medical Imaging, 8(4), 106-113. https://doi.org/10.11648/j.ijmi.20200804.17

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ACS Style

Asmaa Hamdy Mohamed Dkhail; Samah Ahmed Ibrahim Radwan; Hossam Mostafa Gad; Hanan Mohamed Saleh El-Ahwal. Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis. Int. J. Med. Imaging 2020, 8(4), 106-113. doi: 10.11648/j.ijmi.20200804.17

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AMA Style

Asmaa Hamdy Mohamed Dkhail, Samah Ahmed Ibrahim Radwan, Hossam Mostafa Gad, Hanan Mohamed Saleh El-Ahwal. Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis. Int J Med Imaging. 2020;8(4):106-113. doi: 10.11648/j.ijmi.20200804.17

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@article{10.11648/j.ijmi.20200804.17,
  author = {Asmaa Hamdy Mohamed Dkhail and Samah Ahmed Ibrahim Radwan and Hossam Mostafa Gad and Hanan Mohamed Saleh El-Ahwal},
  title = {Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis},
  journal = {International Journal of Medical Imaging},
  volume = {8},
  number = {4},
  pages = {106-113},
  doi = {10.11648/j.ijmi.20200804.17},
  url = {https://doi.org/10.11648/j.ijmi.20200804.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20200804.17},
  abstract = {Imaging of children who had symptoms and signs of pyelonephritis is aimed to diagnosis of renal injury and identification of risk factors for pyelonephritis that might be uncovered during imaging includes vesico- ureteric reflux (VUR). The purpose of this study was to determine the role of static renal scintigraphy in diagnosis of pediatric renal pyelonephritis and the value of single photon emission computed tomography (SPECT) in diagnosis. This study was carried out on 50 patients in Radiology Department at Mansoura Urology and Nephrology center and Radiology department at Tanta university hospitals. High grade vesicoureteric reflux "VUR" (grade IV & V) was detected in 70% of the cases. 42.8% of the cases had vesicoureteric reflux in both kidneys, 42.8% of the cases had VUR only on the left side and 14.2% of the cases had VUR on the right side. A statistical significance was found between grades of pyelonephritis and grades of vescio-ureteric reflux, so there was a strong association between high grade VUR and renal pyelonephritis. It was found that no significant difference was found as regard to the number of abnormal segments detected by static renal scintigraphy and SPECT imaging. Static renal scintigraphy is considered the gold standard for diagnosis of children with pyelonephritis and detection the risk of renal scarring due to recurrent infection. SPECT offers no statistically significant diagnostic advantage over static images for detection of cortical defects.},
 year = {2020}
}

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TY  - JOUR
T1  - Static Renal Scintigraphy in Diagnosis of Pediatric Renal Pyelonephritis
AU  - Asmaa Hamdy Mohamed Dkhail
AU  - Samah Ahmed Ibrahim Radwan
AU  - Hossam Mostafa Gad
AU  - Hanan Mohamed Saleh El-Ahwal
Y1  - 2020/12/11
PY  - 2020
N1  - https://doi.org/10.11648/j.ijmi.20200804.17
DO  - 10.11648/j.ijmi.20200804.17
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 106
EP  - 113
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20200804.17
AB  - Imaging of children who had symptoms and signs of pyelonephritis is aimed to diagnosis of renal injury and identification of risk factors for pyelonephritis that might be uncovered during imaging includes vesico- ureteric reflux (VUR). The purpose of this study was to determine the role of static renal scintigraphy in diagnosis of pediatric renal pyelonephritis and the value of single photon emission computed tomography (SPECT) in diagnosis. This study was carried out on 50 patients in Radiology Department at Mansoura Urology and Nephrology center and Radiology department at Tanta university hospitals. High grade vesicoureteric reflux "VUR" (grade IV & V) was detected in 70% of the cases. 42.8% of the cases had vesicoureteric reflux in both kidneys, 42.8% of the cases had VUR only on the left side and 14.2% of the cases had VUR on the right side. A statistical significance was found between grades of pyelonephritis and grades of vescio-ureteric reflux, so there was a strong association between high grade VUR and renal pyelonephritis. It was found that no significant difference was found as regard to the number of abnormal segments detected by static renal scintigraphy and SPECT imaging. Static renal scintigraphy is considered the gold standard for diagnosis of children with pyelonephritis and detection the risk of renal scarring due to recurrent infection. SPECT offers no statistically significant diagnostic advantage over static images for detection of cortical defects.
VL  - 8
IS  - 4
ER  -

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