| Peer-Reviewed

The Virology, Re-emergence of COVID-19, and Resurgence of Ebola

Received: 21 February 2021    Accepted: 10 September 2021    Published: 31 December 2021
Views:       Downloads:
Abstract

Severe Acute Respiratory Syndrome-Corona virus 2 (SARS-COV-2) is a viral agent capable of causing Corona Virus Disease-2019 (COVID-19) infection. The viral strain was first reported in Wuhan city, China, in 2019 hence the suffix'-19', before it's spread into major parts of the world due to its high risk of transmission via air; this has resulted in the death of over 2.4 Million persons globally. The emergence of infectious diseases is no longer news, as the Ebola virus, which caused another saga of the pandemic, has resurged again in the Democratic Republic of Congo and Guinea. This review article aims to summarize the epidemiology, virology and pathogenesis, treatment, and recommendations to contain and prevent any future pandemic. Ninety percent of the articles used for this short review are within the last 3 years (2019-2021) and from the data correlated it is evident that the factors responsible for this emergence and resurgence are mutation of the etiologic agent, geographical locations, resistance to drugs, lack of adequate post surveillance of infectious diseases, and lifestyle of people in a given locality. Finally, there is a need to implement emergency protocols in all parts of the continent as a nation and no arm of government, be it local, State or federal, is insignificant in the event of an outbreak, a joint force is required to curb and arrest future epidemics as the emergence of COVID-19 and resurgence of the Ebola virus as shown that the current protocols put in place is not full proof.

Published in International Journal of Immunology (Volume 9, Issue 4)
DOI 10.11648/j.iji.20210904.13
Page(s) 79-82
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

COVID-19, Epidemiology, Ebola, Virology

References
[1] World Health Organization Director-General’s Opening Remarks at the Media Briefing on COVID-19–11 March 2020. Available online: https://www.who.int/dg/speeches/detail/who-director-general-s-openingremarks-at-the-media-briefing-on-covid-19---11-march-2020.
[2] Lu, H.; Stratton, C. W.; Tang, Y. W. Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracle. J. Med. Virol. 2020, 92, 401–402.
[3] Comas-Garcia M. Packaging of Genomic RNA in Positive-Sense Single Stranded RNA Viruses: A Complex Story. Viruses. 2019; 11 (3): 253.
[4] World Health Organization, (2021). COVID-19 weekly epidemiological update, 9 March 2021.
[5] Nigeria Center for Disease Control, (2020). Organic Electronics. Retrieved 2 February 2021, from https://ncdc.gov.ng/diseases/sitreps/?cat=14&name=An%20update%20of%20COVID-19%20outbreak%20in%20Nigeria
[6] Spiteri G, Fielding J, Diercke M, Campese C, Enouf V, Gaymard A, et al. First cases of coronavirus disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020. Eurosurveillance. 2020; 25 (9): 2000178.
[7] Riou J, Althaus CL. Pattern of early human-to-human transmission of Wuhan 2019 novel coronavirus (2019-nCoV), December 2019 to January 2020. Euro Surveill. 2020; 25 (4): 2000058.
[8] Horowitz, R. I., Freeman, P. R., & Bruzzese, J. (2020). Efficacy of glutathione therapy in relieving dyspnea associated with COVID-19 pneumonia: A report of 2 cases. Respiratory medicine case reports, 30, 101063.
[9] World Health Organization. (2021). COVID-19 clinical management: living guidance, 25 January 2021 (No. WHO/2019-nCoV/clinical/2021.1). World Health Organization.
[10] Di Gennaro, F., Pizzol, D., Marotta, C., Antunes, M., Racalbuto, V., Veronese, N., & Smith, L. (2020). Coronavirus diseases (COVID-19) current status and future perspectives: a narrative review. International journal of environmental research and public health, 17 (8), 2690.
[11] Singhal T. A Review of Coronavirus Disease-2019 (COVID-19). Ind J Pediatr. 2020; 87 (4): 281–6.
[12] Lalchhandama K (2020). "The chronicles of coronaviruses: the bronchitis, the hepatitis and the common cold". Science Vision. 20 (1): 43–53. doi: 10.33493/scivis.20.01.04.
[13] Lau, Susanna K. P.; Woo, Patrick C. Y.; Yip, Cyril C. Y.; Tse, Herman; Tsoi, Hoi-wah; Cheng, Vincent C. C.; Lee, Paul; Tang, Bone S. F.; Cheung, Chris H. Y.; Lee, Rodney A.; So, Lok-yee (2006). "Coronavirus HKU1 and other coronavirus infections in Hong Kong". Journal of Clinical Microbiology. 44 (6): 2063–2071. doi: 10.1128/JCM.02614-05. PMC 1489438. PMID 16757599.
[14] Sloots, T; McErlean, P; Speicher, D; Arden, K; Nissen, M; MacKay, I (2006). "Evidence of human coronavirus HKU1 and human bocavirus in Australian children". Journal of Clinical Virology. 35 (1): 99–102. doi: 10.1016/j.jcv.2005.09.008. PMC 7108338. PMID 16257260.
[15] Vabret, A.; Dina, J.; Gouarin, S.; Petitjean, J.; Corbet, S.; Freymuth, F. (2006). "Detection of the New Human Coronavirus HKU1: A Report of 6 Cases". Clinical Infectious Diseases. 42 (5): 634–9. doi: 10.1086/500136. PMC 7107802. PMID 16447108.
[16] Esper, Frank; Weibel, Carla; Ferguson, David; Landry, Marie L.; Kahn, Jeffrey S. (2006). "Coronavirus HKU1 Infection in the United States". Emerging Infectious Diseases. 12 (5): 775–9. doi: 10.3201/eid1205.051316. PMC 3374449. PMID 16704837.
[17] Wong J, Koh WC, Momin RN, Alikhan MF, Fadillah N, Naing L. Probable causes and risk factors for positive SARS-CoV-2 test in recovered patients: Evidence from Brunei Darussalam. J Med Virol 2020; 10.1002/jmv. 26199 [PMID: 32558947 DOI: 10.1002/jmv.26199].
[18] Luo S, Guo Y, Zhang X, Xu H. A follow-up study of recovered patients with COVID-19 in Wuhan, China. Int J Infect Dis 2020; 99: 408-409 [PMID: 32497798 DOI: 10.1016/j.ijid.2020.05.119].
[19] Mei Q, Li J, Du R, Yuan X, Li M, Li J. Assessment of patients who tested positive for COVID-19 after recovery. Lancet Infect Dis 2020; 20: 1004-1005 [PMID: 32645295 DOI: 10.1016/S1473-3099(20)30433-3].
[20] Zou Y, Wang BR, Sun L, Xu S, Kong YG, Shen LJ, Liang GT, Chen SM. The issue of recurrently positive patients who recovered from COVID-19 according to the current discharge criteria: investigation of patients from multiple medical institutions in Wuhan, China. J Infect Dis 2020; 222 (11): 1784-1788 [PMID: 32491178 DOI: 10.1093/infdis/jiaa301].
[21] Chen, S., Ren, L. Z., Ouyang, H. S., Liu, S., & Zhang, L. Y. (2021). Necessary problems in re-emergence of COVID-19. World Journal of Clinical Cases, 9 (1), 1.
[22] Amundsen, S. Historical Analysis of the Ebola Virus: Prospective Implications for Primary Care Nursing Today. Clinical Excellence for Nurse Practitioners. Vol 2. No 6. 1998. 343-351.
[23] Baseler L., Chertow D, et. Al. The Pathogenesis of Ebola Virus Disease. Annu. Rev. Pathol. Mech. Dis. 2017. 12: 387–418.
[24] Aborode, A. T., Tsagkaris, C., Jain, S., Ahmad, S., Essar, M. Y., Fajemisin, E. A., ... & Uwishema, O. (2021). Ebola Outbreak amid COVID-19 in the Republic of Guinea: Priorities for Achieving Control. The American journal of tropical medicine and hygiene, 104 (6), 1966.
[25] Onwuakor, C. E. (2014). Ebola Outbreak in Africa: Current Issues–A Mini. American Journal of Medical Case Reports, 2 (9), 184-186.
[26] Dixon, M. G., & Schafer, I. J. (2014). Ebola viral disease outbreak—West Africa, 2014. MMWR. Morbidity and mortality weekly report, 63 (25), 548.
Cite This Article
  • APA Style

    Aigbogun Ighodaro Edwin, Bakare-Akpata Osarobo. (2021). The Virology, Re-emergence of COVID-19, and Resurgence of Ebola. International Journal of Immunology, 9(4), 79-82. https://doi.org/10.11648/j.iji.20210904.13

    Copy | Download

    ACS Style

    Aigbogun Ighodaro Edwin; Bakare-Akpata Osarobo. The Virology, Re-emergence of COVID-19, and Resurgence of Ebola. Int. J. Immunol. 2021, 9(4), 79-82. doi: 10.11648/j.iji.20210904.13

    Copy | Download

    AMA Style

    Aigbogun Ighodaro Edwin, Bakare-Akpata Osarobo. The Virology, Re-emergence of COVID-19, and Resurgence of Ebola. Int J Immunol. 2021;9(4):79-82. doi: 10.11648/j.iji.20210904.13

    Copy | Download

  • @article{10.11648/j.iji.20210904.13,
      author = {Aigbogun Ighodaro Edwin and Bakare-Akpata Osarobo},
      title = {The Virology, Re-emergence of COVID-19, and Resurgence of Ebola},
      journal = {International Journal of Immunology},
      volume = {9},
      number = {4},
      pages = {79-82},
      doi = {10.11648/j.iji.20210904.13},
      url = {https://doi.org/10.11648/j.iji.20210904.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20210904.13},
      abstract = {Severe Acute Respiratory Syndrome-Corona virus 2 (SARS-COV-2) is a viral agent capable of causing Corona Virus Disease-2019 (COVID-19) infection. The viral strain was first reported in Wuhan city, China, in 2019 hence the suffix'-19', before it's spread into major parts of the world due to its high risk of transmission via air; this has resulted in the death of over 2.4 Million persons globally. The emergence of infectious diseases is no longer news, as the Ebola virus, which caused another saga of the pandemic, has resurged again in the Democratic Republic of Congo and Guinea. This review article aims to summarize the epidemiology, virology and pathogenesis, treatment, and recommendations to contain and prevent any future pandemic. Ninety percent of the articles used for this short review are within the last 3 years (2019-2021) and from the data correlated it is evident that the factors responsible for this emergence and resurgence are mutation of the etiologic agent, geographical locations, resistance to drugs, lack of adequate post surveillance of infectious diseases, and lifestyle of people in a given locality. Finally, there is a need to implement emergency protocols in all parts of the continent as a nation and no arm of government, be it local, State or federal, is insignificant in the event of an outbreak, a joint force is required to curb and arrest future epidemics as the emergence of COVID-19 and resurgence of the Ebola virus as shown that the current protocols put in place is not full proof.},
     year = {2021}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - The Virology, Re-emergence of COVID-19, and Resurgence of Ebola
    AU  - Aigbogun Ighodaro Edwin
    AU  - Bakare-Akpata Osarobo
    Y1  - 2021/12/31
    PY  - 2021
    N1  - https://doi.org/10.11648/j.iji.20210904.13
    DO  - 10.11648/j.iji.20210904.13
    T2  - International Journal of Immunology
    JF  - International Journal of Immunology
    JO  - International Journal of Immunology
    SP  - 79
    EP  - 82
    PB  - Science Publishing Group
    SN  - 2329-1753
    UR  - https://doi.org/10.11648/j.iji.20210904.13
    AB  - Severe Acute Respiratory Syndrome-Corona virus 2 (SARS-COV-2) is a viral agent capable of causing Corona Virus Disease-2019 (COVID-19) infection. The viral strain was first reported in Wuhan city, China, in 2019 hence the suffix'-19', before it's spread into major parts of the world due to its high risk of transmission via air; this has resulted in the death of over 2.4 Million persons globally. The emergence of infectious diseases is no longer news, as the Ebola virus, which caused another saga of the pandemic, has resurged again in the Democratic Republic of Congo and Guinea. This review article aims to summarize the epidemiology, virology and pathogenesis, treatment, and recommendations to contain and prevent any future pandemic. Ninety percent of the articles used for this short review are within the last 3 years (2019-2021) and from the data correlated it is evident that the factors responsible for this emergence and resurgence are mutation of the etiologic agent, geographical locations, resistance to drugs, lack of adequate post surveillance of infectious diseases, and lifestyle of people in a given locality. Finally, there is a need to implement emergency protocols in all parts of the continent as a nation and no arm of government, be it local, State or federal, is insignificant in the event of an outbreak, a joint force is required to curb and arrest future epidemics as the emergence of COVID-19 and resurgence of the Ebola virus as shown that the current protocols put in place is not full proof.
    VL  - 9
    IS  - 4
    ER  - 

    Copy | Download

Author Information
  • Edo State Government House, Benin, Nigeria

  • Department of Biochemistry, College of Science and Technology Covenant University, Ota, Nigeria

  • Sections