Resistance of Strains of <i>Pseudomonas aeruginosa</i> to Antibiotics in N'Djamena in Chad

Ahmat Mahamat Ahmat; Adoum Fouda Abderrazzack; Abdelsalam Tidjani; Brahim Boy Otchom; Aly Savadogo

doi:doi:10.11648/j.ijbmr.20210902.14

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Resistance of Strains of Pseudomonas aeruginosa to Antibiotics in N'Djamena in Chad

Ahmat Mahamat Ahmat, Adoum Fouda Abderrazzack, Abdelsalam Tidjani, Brahim Boy Otchom, Aly Savadogo

Published in International Journal of Biomedical Materials Research (Volume 9, Issue 2)

Received: 4 October 2021 Accepted: 25 October 2021 Published: 24 December 2021

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Abstract

The objective of this study is to determine the resistance profile of Pseudomonas aeruginosa strains towards antibiotics in N'Djamena (CHAD). This a cross-sectional and prospective study, conducted at the Mother and Child Hospital (MCH) in N'djamena, from February to July 2016 on 550 urine samples. Uroculture and antibiotic susceptibility testing were performed according to MCH laboratory standards. Germ isolation was performed on Cetrimide agar and identification by API 20 NE gallery. The antibiogram was determined by the microgram method on Mueller-Hinton agar. A total of 15/550 (2.72%) strains of Pseudomonas aeruginosa were identified. These strains showed low resistance between 6.66% and 13.33% to Cefixime, Colistin, Gentamycin, Ciprofloxacin and Tobramycin. On the other hand, a high resistance (100%) was observed with Augmentin, Ampicillin, Cefotaxime, Ceftriaxone, Imipenem, Vancomycin, Oxacillin, Erythromycin and Tetracycline. The emergence of multiresistant bacterial strains is a major public health problem that requires adequate and adapted antibiotic therapy. Pseudomonas aeruginosa is one of the bacteria whose monitoring is more than necessary to defect the appearance of multidrug resistant strains. Given the involvement of Pseudomonas aeruginosa in several infectious pathologies, a monitoring of its profile with respect to antibiotics must be systematically carried out in all the health structures that have adequate technical platforms allowing them to perform an antibiogram.

Published in	International Journal of Biomedical Materials Research (Volume 9, Issue 2)
DOI	10.11648/j.ijbmr.20210902.14
Page(s)	26-30
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Resistance, Antibiotics, Urine, Pseudomonas aeruginosa

References

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APA Style

Ahmat Mahamat Ahmat, Adoum Fouda Abderrazzack, Abdelsalam Tidjani, Brahim Boy Otchom, Aly Savadogo. (2021). Resistance of Strains of Pseudomonas aeruginosa to Antibiotics in N'Djamena in Chad. International Journal of Biomedical Materials Research, 9(2), 26-30. https://doi.org/10.11648/j.ijbmr.20210902.14

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ACS Style

Ahmat Mahamat Ahmat; Adoum Fouda Abderrazzack; Abdelsalam Tidjani; Brahim Boy Otchom; Aly Savadogo. Resistance of Strains of Pseudomonas aeruginosa to Antibiotics in N'Djamena in Chad. Int. J. Biomed. Mater. Res. 2021, 9(2), 26-30. doi: 10.11648/j.ijbmr.20210902.14

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AMA Style

Ahmat Mahamat Ahmat, Adoum Fouda Abderrazzack, Abdelsalam Tidjani, Brahim Boy Otchom, Aly Savadogo. Resistance of Strains of Pseudomonas aeruginosa to Antibiotics in N'Djamena in Chad. Int J Biomed Mater Res. 2021;9(2):26-30. doi: 10.11648/j.ijbmr.20210902.14

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@article{10.11648/j.ijbmr.20210902.14,
  author = {Ahmat Mahamat Ahmat and Adoum Fouda Abderrazzack and Abdelsalam Tidjani and Brahim Boy Otchom and Aly Savadogo},
  title = {Resistance of Strains of Pseudomonas aeruginosa to Antibiotics in N'Djamena in Chad},
  journal = {International Journal of Biomedical Materials Research},
  volume = {9},
  number = {2},
  pages = {26-30},
  doi = {10.11648/j.ijbmr.20210902.14},
  url = {https://doi.org/10.11648/j.ijbmr.20210902.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbmr.20210902.14},
  abstract = {The objective of this study is to determine the resistance profile of Pseudomonas aeruginosa strains towards antibiotics in N'Djamena (CHAD). This a cross-sectional and prospective study, conducted at the Mother and Child Hospital (MCH) in N'djamena, from February to July 2016 on 550 urine samples. Uroculture and antibiotic susceptibility testing were performed according to MCH laboratory standards. Germ isolation was performed on Cetrimide agar and identification by API 20 NE gallery. The antibiogram was determined by the microgram method on Mueller-Hinton agar. A total of 15/550 (2.72%) strains of Pseudomonas aeruginosa were identified. These strains showed low resistance between 6.66% and 13.33% to Cefixime, Colistin, Gentamycin, Ciprofloxacin and Tobramycin. On the other hand, a high resistance (100%) was observed with Augmentin, Ampicillin, Cefotaxime, Ceftriaxone, Imipenem, Vancomycin, Oxacillin, Erythromycin and Tetracycline. The emergence of multiresistant bacterial strains is a major public health problem that requires adequate and adapted antibiotic therapy. Pseudomonas aeruginosa is one of the bacteria whose monitoring is more than necessary to defect the appearance of multidrug resistant strains. Given the involvement of Pseudomonas aeruginosa in several infectious pathologies, a monitoring of its profile with respect to antibiotics must be systematically carried out in all the health structures that have adequate technical platforms allowing them to perform an antibiogram.},
 year = {2021}
}

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TY - JOUR
T1 - Resistance of Strains of Pseudomonas aeruginosa to Antibiotics in N'Djamena in Chad
AU - Ahmat Mahamat Ahmat
AU - Adoum Fouda Abderrazzack
AU - Abdelsalam Tidjani
AU - Brahim Boy Otchom
AU - Aly Savadogo
Y1 - 2021/12/24
PY - 2021
N1 - https://doi.org/10.11648/j.ijbmr.20210902.14
DO - 10.11648/j.ijbmr.20210902.14
T2 - International Journal of Biomedical Materials Research
JF - International Journal of Biomedical Materials Research
JO - International Journal of Biomedical Materials Research
SP - 26
EP - 30
PB - Science Publishing Group
SN - 2330-7579
UR - https://doi.org/10.11648/j.ijbmr.20210902.14
AB - The objective of this study is to determine the resistance profile of Pseudomonas aeruginosa strains towards antibiotics in N'Djamena (CHAD). This a cross-sectional and prospective study, conducted at the Mother and Child Hospital (MCH) in N'djamena, from February to July 2016 on 550 urine samples. Uroculture and antibiotic susceptibility testing were performed according to MCH laboratory standards. Germ isolation was performed on Cetrimide agar and identification by API 20 NE gallery. The antibiogram was determined by the microgram method on Mueller-Hinton agar. A total of 15/550 (2.72%) strains of Pseudomonas aeruginosa were identified. These strains showed low resistance between 6.66% and 13.33% to Cefixime, Colistin, Gentamycin, Ciprofloxacin and Tobramycin. On the other hand, a high resistance (100%) was observed with Augmentin, Ampicillin, Cefotaxime, Ceftriaxone, Imipenem, Vancomycin, Oxacillin, Erythromycin and Tetracycline. The emergence of multiresistant bacterial strains is a major public health problem that requires adequate and adapted antibiotic therapy. Pseudomonas aeruginosa is one of the bacteria whose monitoring is more than necessary to defect the appearance of multidrug resistant strains. Given the involvement of Pseudomonas aeruginosa in several infectious pathologies, a monitoring of its profile with respect to antibiotics must be systematically carried out in all the health structures that have adequate technical platforms allowing them to perform an antibiogram.
VL - 9
IS - 2
ER -

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Author Information

Ahmat Mahamat Ahmat

Laboratory of the Mother and Child Hospital, University of N'Djamena, N'Djamena, Chad
Adoum Fouda Abderrazzack

Sectoral Program for the Fight Against HIV/AIDS and Sexually Transmitted Infections, N'djamena, Chad
Abdelsalam Tidjani

Department of Public Health, Faculty of Sciences and Human Health, University of N'Djamena, N'Djamena, Chad
Brahim Boy Otchom

Biomedical Sciences, Faculty of Sciences, Toumai University, Ndjamena, Chad
Aly Savadogo

Biochemistry Microbiology, Faculty of Sciences, Joseph Ki-Zerbo, Ouagadougou, Burkina Faso

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APA Style

Ahmat Mahamat Ahmat, Adoum Fouda Abderrazzack, Abdelsalam Tidjani, Brahim Boy Otchom, Aly Savadogo. (2021). Resistance of Strains of Pseudomonas aeruginosa to Antibiotics in N'Djamena in Chad. International Journal of Biomedical Materials Research, 9(2), 26-30. https://doi.org/10.11648/j.ijbmr.20210902.14

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ACS Style

Ahmat Mahamat Ahmat; Adoum Fouda Abderrazzack; Abdelsalam Tidjani; Brahim Boy Otchom; Aly Savadogo. Resistance of Strains of Pseudomonas aeruginosa to Antibiotics in N'Djamena in Chad. Int. J. Biomed. Mater. Res. 2021, 9(2), 26-30. doi: 10.11648/j.ijbmr.20210902.14

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AMA Style

Ahmat Mahamat Ahmat, Adoum Fouda Abderrazzack, Abdelsalam Tidjani, Brahim Boy Otchom, Aly Savadogo. Resistance of Strains of Pseudomonas aeruginosa to Antibiotics in N'Djamena in Chad. Int J Biomed Mater Res. 2021;9(2):26-30. doi: 10.11648/j.ijbmr.20210902.14

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@article{10.11648/j.ijbmr.20210902.14,
  author = {Ahmat Mahamat Ahmat and Adoum Fouda Abderrazzack and Abdelsalam Tidjani and Brahim Boy Otchom and Aly Savadogo},
  title = {Resistance of Strains of Pseudomonas aeruginosa to Antibiotics in N'Djamena in Chad},
  journal = {International Journal of Biomedical Materials Research},
  volume = {9},
  number = {2},
  pages = {26-30},
  doi = {10.11648/j.ijbmr.20210902.14},
  url = {https://doi.org/10.11648/j.ijbmr.20210902.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbmr.20210902.14},
  abstract = {The objective of this study is to determine the resistance profile of Pseudomonas aeruginosa strains towards antibiotics in N'Djamena (CHAD). This a cross-sectional and prospective study, conducted at the Mother and Child Hospital (MCH) in N'djamena, from February to July 2016 on 550 urine samples. Uroculture and antibiotic susceptibility testing were performed according to MCH laboratory standards. Germ isolation was performed on Cetrimide agar and identification by API 20 NE gallery. The antibiogram was determined by the microgram method on Mueller-Hinton agar. A total of 15/550 (2.72%) strains of Pseudomonas aeruginosa were identified. These strains showed low resistance between 6.66% and 13.33% to Cefixime, Colistin, Gentamycin, Ciprofloxacin and Tobramycin. On the other hand, a high resistance (100%) was observed with Augmentin, Ampicillin, Cefotaxime, Ceftriaxone, Imipenem, Vancomycin, Oxacillin, Erythromycin and Tetracycline. The emergence of multiresistant bacterial strains is a major public health problem that requires adequate and adapted antibiotic therapy. Pseudomonas aeruginosa is one of the bacteria whose monitoring is more than necessary to defect the appearance of multidrug resistant strains. Given the involvement of Pseudomonas aeruginosa in several infectious pathologies, a monitoring of its profile with respect to antibiotics must be systematically carried out in all the health structures that have adequate technical platforms allowing them to perform an antibiogram.},
 year = {2021}
}

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