Kounis syndrome is a hypersensitivity coronary disorder associated with several triggers, such as drugs, foods, environmental, coronary stents and other factors. It was originally proposed by the Greek cardiologist Nicholas Kounis in 1991. Kounis syndrome is a life-threatening and challenging emergency disease, which is constantly being recognized and studied. It is a disease that is constantly being recognized and Kounis syndrome can be classified into three types, involving coronary artery spasm, plaque rupture or stent thrombosis respectively. Most patients with coronary artery spasm caused by allergies can recover completely after active treatment, and the prognosis is good. If not, it may cause severe myocardial damage and even myocardial infarction, which threatens the patient's life. In our case, a 56-year-old female patient was scheduled to undergo right pelvic resection. A few minutes after the start of intravenous succinylated gelatin infusion, she was experienced a decrease in heart rate, blood pressure, oxygen saturation and ST elevation on 2-lead. An anaphylactic reaction was suspected after rapid differential diagnosis and gradually recovered with treatment. In this context, a rapid differential diagnosis and a highly suspicious become essential, because the management of Kounis syndrome is different from the traditional acute coronary syndrome. Kounis syndrome requires simultaneous diagnosis and treatment of both allergic reaction and acute coronary syndrome based on their manifestations and risk factors. This case describes the onset, development, and recovery of Kounis syndrome in this patient in detail, and illustrates the classification, pathophysiology, and treatment of Kounis syndrome. It is hoped that through the management of this case, the occurrence of Kounis syndrome can be rapidly identified and treated accordingly so that avoiding disaster for patients.
| Published in | International Journal of Anesthesia and Clinical Medicine (Volume 11, Issue 1) |
| DOI | 10.11648/j.ijacm.20231101.15 |
| Page(s) | 23-27 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Kounis Syndrome, Anaphylaxis, Gelofusine
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| [2] | M. Abdelghany, R. Subedi, S. Shah, and H. Kozman, “Kounis syndrome: A review article on epidemiology, diagnostic findings, management and complications of allergic acute coronary syndrome.” International Journal of Cardiology, vol. 232, pp. 1–4, 2017. |
| [3] | M. Giovannini et al., “Kounis syndrome: a clinical entity penetrating from pediatrics to geriatrics,” J Geriatr Cardiol, vol. 17, no. 5, pp. 294–299, May 2020. |
| [4] | B. Dai, J. Cavaye, M. Judd, J. Beuth, H. Iswariah, and U. Gurunathan, “Perioperative Presentations of Kounis Syndrome: A Systematic Literature Review,” J Cardiothorac Vasc Anesth, vol. 36, no. 7, pp. 2070–2076, Jul. 2022. |
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| [7] | Pascale Dewachter, “Anaphylaxis and Anesthesia: Controversies and New Insights,” Survey of Anesthesiology, vol. 54, no. 4, pp. 186–187, Aug. 2010. |
| [8] | S. Vaina et al., “Anaphylactic cardiovascular collapse manifesting as myocardial infarction following salad consumption. A case of Kounis variant type I syndrome,” Acta Biomed, vol. 91, no. 1, pp. 134–138, 2020. |
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APA Style
Peipei Sun, Tao Zhu. (2023). A Case of Kounis Syndrome Caused by Anaphylaxis During Surgery. International Journal of Anesthesia and Clinical Medicine, 11(1), 23-27. https://doi.org/10.11648/j.ijacm.20231101.15
ACS Style
Peipei Sun; Tao Zhu. A Case of Kounis Syndrome Caused by Anaphylaxis During Surgery. Int. J. Anesth. Clin. Med. 2023, 11(1), 23-27. doi: 10.11648/j.ijacm.20231101.15
AMA Style
Peipei Sun, Tao Zhu. A Case of Kounis Syndrome Caused by Anaphylaxis During Surgery. Int J Anesth Clin Med. 2023;11(1):23-27. doi: 10.11648/j.ijacm.20231101.15
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Download@article{10.11648/j.ijacm.20231101.15,
author = {Peipei Sun and Tao Zhu},
title = {A Case of Kounis Syndrome Caused by Anaphylaxis During Surgery},
journal = {International Journal of Anesthesia and Clinical Medicine},
volume = {11},
number = {1},
pages = {23-27},
doi = {10.11648/j.ijacm.20231101.15},
url = {https://doi.org/10.11648/j.ijacm.20231101.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijacm.20231101.15},
abstract = {Kounis syndrome is a hypersensitivity coronary disorder associated with several triggers, such as drugs, foods, environmental, coronary stents and other factors. It was originally proposed by the Greek cardiologist Nicholas Kounis in 1991. Kounis syndrome is a life-threatening and challenging emergency disease, which is constantly being recognized and studied. It is a disease that is constantly being recognized and Kounis syndrome can be classified into three types, involving coronary artery spasm, plaque rupture or stent thrombosis respectively. Most patients with coronary artery spasm caused by allergies can recover completely after active treatment, and the prognosis is good. If not, it may cause severe myocardial damage and even myocardial infarction, which threatens the patient's life. In our case, a 56-year-old female patient was scheduled to undergo right pelvic resection. A few minutes after the start of intravenous succinylated gelatin infusion, she was experienced a decrease in heart rate, blood pressure, oxygen saturation and ST elevation on 2-lead. An anaphylactic reaction was suspected after rapid differential diagnosis and gradually recovered with treatment. In this context, a rapid differential diagnosis and a highly suspicious become essential, because the management of Kounis syndrome is different from the traditional acute coronary syndrome. Kounis syndrome requires simultaneous diagnosis and treatment of both allergic reaction and acute coronary syndrome based on their manifestations and risk factors. This case describes the onset, development, and recovery of Kounis syndrome in this patient in detail, and illustrates the classification, pathophysiology, and treatment of Kounis syndrome. It is hoped that through the management of this case, the occurrence of Kounis syndrome can be rapidly identified and treated accordingly so that avoiding disaster for patients.},
year = {2023}
}
TY - JOUR T1 - A Case of Kounis Syndrome Caused by Anaphylaxis During Surgery AU - Peipei Sun AU - Tao Zhu Y1 - 2023/04/11 PY - 2023 N1 - https://doi.org/10.11648/j.ijacm.20231101.15 DO - 10.11648/j.ijacm.20231101.15 T2 - International Journal of Anesthesia and Clinical Medicine JF - International Journal of Anesthesia and Clinical Medicine JO - International Journal of Anesthesia and Clinical Medicine SP - 23 EP - 27 PB - Science Publishing Group SN - 2997-2698 UR - https://doi.org/10.11648/j.ijacm.20231101.15 AB - Kounis syndrome is a hypersensitivity coronary disorder associated with several triggers, such as drugs, foods, environmental, coronary stents and other factors. It was originally proposed by the Greek cardiologist Nicholas Kounis in 1991. Kounis syndrome is a life-threatening and challenging emergency disease, which is constantly being recognized and studied. It is a disease that is constantly being recognized and Kounis syndrome can be classified into three types, involving coronary artery spasm, plaque rupture or stent thrombosis respectively. Most patients with coronary artery spasm caused by allergies can recover completely after active treatment, and the prognosis is good. If not, it may cause severe myocardial damage and even myocardial infarction, which threatens the patient's life. In our case, a 56-year-old female patient was scheduled to undergo right pelvic resection. A few minutes after the start of intravenous succinylated gelatin infusion, she was experienced a decrease in heart rate, blood pressure, oxygen saturation and ST elevation on 2-lead. An anaphylactic reaction was suspected after rapid differential diagnosis and gradually recovered with treatment. In this context, a rapid differential diagnosis and a highly suspicious become essential, because the management of Kounis syndrome is different from the traditional acute coronary syndrome. Kounis syndrome requires simultaneous diagnosis and treatment of both allergic reaction and acute coronary syndrome based on their manifestations and risk factors. This case describes the onset, development, and recovery of Kounis syndrome in this patient in detail, and illustrates the classification, pathophysiology, and treatment of Kounis syndrome. It is hoped that through the management of this case, the occurrence of Kounis syndrome can be rapidly identified and treated accordingly so that avoiding disaster for patients. VL - 11 IS - 1 ER -
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